Results 61 to 70 of about 33,221 (207)
Recent Advances in Traditional Chinese Medicine for Treatment of Podocyte Injury
Frontiers in Pharmacology, 2022 Podocyte is also called glomerular epithelial cell, which has been considered as the final gatekeeper of glomerular filtration barrier (GFB). As a major contributor to proteinuria, podocyte injury underlies a variety of glomerular diseases and becomes ...
Tianwen Yao +6 more
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Identification of novel podocyte stress-response mechanisms in vitro
, 2019 Although podocyte injury has been correlated with glomerular disease progression, the mechanisms underlying podocyte response to stress in vivo remain poorly understood.
Haley, Kathryn Elizabeth
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Role of the podocyte in proteinuria [PDF]
Pediatric Nephrology, 2011 In recent years, the podocyte, with its elaborate cytoarchitecture and slit diaphragm, has been the focus of extensive research, yet its precise role in the glomerular filtration barrier is still debated. There are puzzling observations indicating that a comprehensive mechanistic model for glomerular filtration is still necessary.
Menzel, Sylvia, Moeller, Marcus J.
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Effect of N-acetyl-seryl-aspartyl-lysyl-proline on high glucose-induced podocyte injury
Linchuang shenzangbing zazhi, 2018 Objective To investigate the effect of N-acetyl-seryl-aspartyl-lysyl-proline(AcSDKP) on podocyte injury induced by high glucose and its possible mechanisms.Methods The conditionally immortalized mouse podocytes were treated by high glucose with or ...
ZHA Dong-qing, GAO Ping, WU Xiao-yan
doaj
Everolimus Stabilizes Podocyte Microtubules via Enhancing TUBB2B and DCDC2 Expression. [PDF]
PLoS ONE, 2015 Glomerular podocytes are highly differentiated cells that are key components of the kidney filtration units. The podocyte cytoskeleton builds the basis for the dynamic podocyte cytoarchitecture and plays a central role for proper podocyte function ...
Stefanie Jeruschke +10 more
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Producing Purer Podocytes [PDF]
Journal of the American Society of Nephrology, 2019 Podocytes are highly specialized cells that play a central role in many renal disorders. For many years, podocyte research has been stymied by an inability to culture these cells in a well differentiated state.
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Cellular Physiology and Biochemistry, 2014 Background: Decreased expression of α3β1 integrin may contribute to reduction in podocyte adhesion to glomerular basement membrane (GBM), which represents a novel early mechanism leading to diabetic kidney disease (DKD).
Dingkun Gui +5 more
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The Role of the Podocyte in Preeclampsia [PDF]
Clinical Journal of the American Society of Nephrology, 2014 Preeclampsia is a pregnancy-specific hypertensive disorder that affects approximately 5% of pregnancies and remains one of the leading causes of both maternal and fetal morbidity and mortality worldwide ([1][1]).
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The function of endocytosis in podocytes [PDF]
Current Opinion in Nephrology & Hypertension, 2013 In this review, we discuss the role of endocytosis, a fundamental process internalizing molecules from the plasma membrane, and its critical importance in podocyte biology.Endocytic clathrin and nonclathrin-coated pits have been visualized in podocytes using electron microscopy, but the functional biological relevance has not been well defined.
Keita, Soda, Shuta, Ishibe
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Systemic gene therapy with thymosin β4 alleviates glomerular injury in mice
Scientific Reports, 2022 Plasma ultrafiltration in the kidney occurs across glomerular capillaries, which are surrounded by epithelial cells called podocytes. Podocytes have a unique shape maintained by a complex cytoskeleton, which becomes disrupted in glomerular disease ...
William J. Mason +13 more
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