Results 151 to 160 of about 28,951 (302)
Cordycepin nephroprotection: From STZ mouse to human T2D
Journal of Diabetes Investigation, EarlyView.
Jing Yang
wiley +1 more source
In this study, an adaptive antioxidant nanodrug (AAN) is developed through the self‐polymerization of L‐selenocysteine. The AAN exhibits dual functionalities: antioxidant activity (scavenging reactive oxygen species) and mitochondrial targeting. Moreover, the released selenium (Se) participates in the synthesis of glutathione peroxidase 4 (GPX4), which
Zerun Liu +15 more
wiley +1 more source
Diabetic kidney disease (DKD) is a common chronic microvascular complication of diabetes mellitus. Although studies have indicated the therapeutic potential of mesenchymal stem cells (MSCs) for DKD, the underlying molecular mechanisms remain unclear ...
Honghong Liu +3 more
doaj +1 more source
Inhibition of AMPKα Pathway by Podocyte GOLM1 Exacerbates Diabetic Nephrology in Mice
Podocyte Golgi membrane protein 1 interacts with epidermal growth factor receptor to inhibit peroxisome proliferator activated receptor γ, and then inactivates adenosine monophosphate activated protein kinase α pathway, which facilitates diabetes‐related inflammation, oxidative damage, apoptosis, and renal dysfunction.
Peng Xu +14 more
wiley +1 more source
Podocyte Repopulation Contributes to Regression of Glomerular Injury Induced by Ace Inhibition [PDF]
Daniela Macconi +7 more
openalex +1 more source
Modulation of Aging Diseases via RAGE Targets: A Dietary Intervention Review
This paper analyzes RAGE ligand‐binding mechanisms and signaling, proposing intervention strategies targeting these interactions. It emphasizes dietary polyphenols, polysaccharides, and terpenoids delivered via functional foods for anti‐aging. These compounds offer long‐term, safe intervention through dietary supplementation, providing dual nutritional
Qian Wu +7 more
wiley +1 more source
R168H and V165X mutant podocin might induce different degrees of podocyte injury via different molecular mechanisms [PDF]
Qingfeng Fan +7 more
openalex +1 more source
New Ways of Thinking about Proteinuria and Progression of Renal Damage [PDF]
Turner, Neil, Zhou, Y. S.
core +1 more source
Distinct Roles for Basal and Induced COX-2 in Podocyte Injury [PDF]
Huifang Cheng +5 more
openalex +1 more source
Objective This study characterized the impact of voclosporin on kidney histology in patients with lupus nephritis (LN) who had protocolized repeat kidney biopsies in the AURORA clinical trials. Methods Patients were randomized to voclosporin or placebo treatment for up to 3 years; all patients received mycophenolate mofetil and low‐dose glucocorticoids.
Brad H. Rovin +9 more
wiley +1 more source

