Results 151 to 160 of about 28,951 (302)

Cordycepin nephroprotection: From STZ mouse to human T2D

open access: yes
Journal of Diabetes Investigation, EarlyView.
Jing Yang
wiley   +1 more source

Adaptive Antioxidant Nanomedicines Inhibit Ferroptosis in Renal Tubular Epithelial Cells to Alleviate Diabetic Kidney Disease

open access: yesAdvanced Science, Volume 12, Issue 37, October 6, 2025.
In this study, an adaptive antioxidant nanodrug (AAN) is developed through the self‐polymerization of L‐selenocysteine. The AAN exhibits dual functionalities: antioxidant activity (scavenging reactive oxygen species) and mitochondrial targeting. Moreover, the released selenium (Se) participates in the synthesis of glutathione peroxidase 4 (GPX4), which
Zerun Liu   +15 more
wiley   +1 more source

Placenta-derived mesenchymal stem cells protect against diabetic kidney disease by upregulating autophagy-mediated SIRT1/FOXO1 pathway

open access: yesRenal Failure
Diabetic kidney disease (DKD) is a common chronic microvascular complication of diabetes mellitus. Although studies have indicated the therapeutic potential of mesenchymal stem cells (MSCs) for DKD, the underlying molecular mechanisms remain unclear ...
Honghong Liu   +3 more
doaj   +1 more source

Inhibition of AMPKα Pathway by Podocyte GOLM1 Exacerbates Diabetic Nephrology in Mice

open access: yesAdvanced Science, Volume 12, Issue 37, October 6, 2025.
Podocyte Golgi membrane protein 1 interacts with epidermal growth factor receptor to inhibit peroxisome proliferator activated receptor γ, and then inactivates adenosine monophosphate activated protein kinase α pathway, which facilitates diabetes‐related inflammation, oxidative damage, apoptosis, and renal dysfunction.
Peng Xu   +14 more
wiley   +1 more source

Podocyte Repopulation Contributes to Regression of Glomerular Injury Induced by Ace Inhibition [PDF]

open access: bronze, 2009
Daniela Macconi   +7 more
openalex   +1 more source

Modulation of Aging Diseases via RAGE Targets: A Dietary Intervention Review

open access: yesAdvanced Science, Volume 12, Issue 38, October 13, 2025.
This paper analyzes RAGE ligand‐binding mechanisms and signaling, proposing intervention strategies targeting these interactions. It emphasizes dietary polyphenols, polysaccharides, and terpenoids delivered via functional foods for anti‐aging. These compounds offer long‐term, safe intervention through dietary supplementation, providing dual nutritional
Qian Wu   +7 more
wiley   +1 more source

R168H and V165X mutant podocin might induce different degrees of podocyte injury via different molecular mechanisms [PDF]

open access: bronze, 2009
Qingfeng Fan   +7 more
openalex   +1 more source

Distinct Roles for Basal and Induced COX-2 in Podocyte Injury [PDF]

open access: bronze, 2009
Huifang Cheng   +5 more
openalex   +1 more source

Effect of Long‐Term Voclosporin Treatment on Renal Histology in Patients With Active Lupus Nephritis With Repeat Renal Biopsies

open access: yesArthritis &Rheumatology, Volume 77, Issue 10, Page 1387-1393, October 2025.
Objective This study characterized the impact of voclosporin on kidney histology in patients with lupus nephritis (LN) who had protocolized repeat kidney biopsies in the AURORA clinical trials. Methods Patients were randomized to voclosporin or placebo treatment for up to 3 years; all patients received mycophenolate mofetil and low‐dose glucocorticoids.
Brad H. Rovin   +9 more
wiley   +1 more source

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