Immunogenicity of sequential inactivated and oral poliovirus vaccines (OPV) versus inactivated poliovirus vaccine (IPV) alone in healthy infants: A systematic review and meta-analysis [PDF]
Human Vaccines & Immunotherapeutics, 2018 Background: The emergence of vaccine-associated paralytic poliomyelitis has become an ongoing burden of poliomyelitis. During this special period from OPV to IPV-only immunization schedule, we did a meta-analysis to compare the immunogenicity of ...
Guihua Tang +8 more
doaj +3 more sources
Development of RT-PCR Assays for Simple Detection and Identification of Sabin Virus Contaminants in the Novel Oral Poliovirus Vaccines [PDF]
VaccinesBackground/Objectives: Conventional live oral poliovirus vaccines (OPVs) effectively prevent poliomyelitis. These vaccines are derived from three attenuated Sabin strains of poliovirus, which can revert within the first week of replication to a ...
Majid Laassri +2 more
exaly +3 more sources
The effect of maternal poliovirus antibodies on the immune responses of infants to poliovirus vaccines [PDF]
BMC Infectious Diseases, 2020 Background Maternal poliovirus antibodies could provide passive immunity to the newborns from poliovirus infection during their first few months of life, but they may impair the immune responses of infants to the poliovirus vaccine as well. In our study,
Siyue Jia +4 more
doaj +2 more sources
Comparison of the Immunogenicity and Safety of Three Enhanced Inactivated Poliovirus Vaccines from Different Manufacturers in Healthy Korean Infants: A Prospective Multicenter Study [PDF]
Vaccines, 2020 The enhanced inactivated poliovirus vaccine was first introduced in 2002, and several inactivated poliovirus vaccines are licensed in Korea. Reliable data by a prospective study on the immunogenicity and safety of the inactivated poliovirus vaccines in ...
Byung Ok Kwak +8 more
doaj +2 more sources
Enterovirus virus-like-particle and inactivated poliovirus vaccines do not elicit substantive cross-reactive antibody responses [PDF]
PLoS PathogensHuman enteroviruses are the most common human pathogen with over 300 distinct genotypes. Previous work with poliovirus has suggested that it is possible to generate antibody responses in humans and animals that can recognize members of multiple ...
Daniel Moss +2 more
exaly +3 more sources
Research Progress Towards Poliovirus Virus-like Particle Vaccines: A Review [PDF]
VaccinesPoliovirus (PV), a historically significant enterovirus responsible for severe paralytic diseases, has seen its incidence dramatically reduced through widespread vaccination efforts, propelling global eradication initiatives.
Taoli Han +5 more
doaj +2 more sources
A Panel of VHH Antibodies Against Sabin Type 1 Poliovirus D-Antigen Reveals Strain-Specific and Cross-Serotype Reactivity [PDF]
VirusesVaccination remains the primary strategy for poliomyelitis prevention. The D-antigen of poliovirus is a critical component of inactivated polio vaccines, as it induces the production of neutralizing antibodies and provides protective immunity. Therefore,
Maya Ermakova +13 more
doaj +2 more sources
The Pathology of Poliomyelitis and the Vaccines and Nonvaccine Therapy [PDF]
E3S Web of Conferences, 2021 Poliomyelitis is an exclusively human disease that mainly affects children. Clinical features of poliomyelitis can be varied, from mild illness to the most severe paralysis, and the factor why poliomyelitis has different performances in individuals has ...
Chen Yushuo, Yue Tianrui, Zhang Zixiao
doaj +1 more source
The role of a genetically stable, novel oral type 2 poliovirus vaccine in the poliomyelitis endgame
Revista Panamericana de Salud Pública, 2023 Poliovirus infection causes paralysis in up to 1 in 200 infected persons. The use of safe and effective inactivated poliovirus vaccines and live attenuated oral poliovirus vaccines (OPVs) means that only two pockets of wildtype poliovirus type 1 remain ...
Sue Ann Costa Clemens +3 more
doaj +1 more source
The safety and immunogenicity of two novel live attenuated monovalent (serotype 2) oral poliovirus vaccines in healthy adults: a double-blind, single-centre phase 1 study [PDF]
Lancet, The, 2019 Raúl Andino +2 more
exaly +2 more sources