Results 11 to 20 of about 218,086 (209)

Simian virus 40, poliovirus vaccines, and human cancer: research progress versus media and public interests

Bulletin of the World Health Organization, 2000
From 1955 through early 1963, millions of people were inadvertently exposed to simian virus 40 (SV40) as a contaminant of poliovirus vaccines; the virus had been present in the monkey kidney cultures used to prepare the vaccines and had escaped detection.
J.S. Butel
doaj   +1 more source

Intestinal Antibody Responses to 2 Novel Live Attenuated Type 2 Oral Poliovirus Vaccines in Healthy Adults in Belgium. [PDF]

J Infect Dis, 2022
: In a blinded phase 1 trial (EudraCT 2017-0000908-21; NCT03430349) in Belgium, healthy adults (aged 18-50 years) previously immunized exclusively with inactivated poliovirus vaccine were administered a single dose of 1 of 2 novel type 2 oral poliovirus ...
Brickley EB, Connor RI, Wieland-Alter W, Weiner JA, Ackerman ME, Arita M, Gast C, De Coster I, Van Damme P, Bandyopadhyay AS, Wright PF.   +10 more
europepmc   +2 more sources

Enterovirus infections in children. [PDF]

Pediatr Investig
Enteroviruses (EVs) are major pathogens causing a wide spectrum of diseases in children worldwide. This review summarizes the epidemiology, virology, viral replication, and virus‐host interactions of EVs. It also highlights current advances in clinical diagnosis, antiviral therapies, and vaccine development, providing insights into future strategies ...
Chen X, Guo L, Lei X, Zhao L, Hei M, Shen J, Yin J, Li F, Deng J, Liu G, Zhang Y, Xie Z.   +11 more
europepmc   +2 more sources

Glyceraldehyde-3-phosphate dehydrogenase common peptides of listeria monocytogenes, mycobacterium marinum and streptococcus pneumoniae as universal vaccines [PDF]

, 2021
Universal vaccines can be prepared with antigens common to different pathogens. In this regard, the glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a common virulence factor among pathogenic bacteria of the genera Listeria, Mycobacterium and ...
Del Molino-Bernal, I. Concepción Pérez, Torres-Rodriguez, Paula, Calvo-Montes, Jorge, David Salcines-Cuevas, Pérez Del Molino-Bernal, Concepción, Ricardo Calderón-Gonzalez, Manuel Fresno, Álvarez-Domínguez, Carmen, Teran-Navarro, Héctor, Fresno, Manuel, Raquel Tobes, Molino-Bernal, I Concepción Pérez Del, Paula Torres-Rodriguez, Carmen Alvarez-Dominguez, I. Concepción Pérez Del Molino-Bernal, Salcines-Cuevas, David, Fresno Escudero, Manuel, Pérez Del Molino Bernal, I. Concepción, Hector Terán-Navarro, Yañez-Diaz, Sonsoles, Jorge Calvo-Montes, Sonsoles Yañez-Diaz, Calderón-González, Ricardo, Tobes, Raquel   +23 more
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Mucosal immunity to poliovirus. [PDF]

, 2021
A cornerstone of the global initiative to eradicate polio is the widespread use of live and inactivated poliovirus vaccines in extensive public health campaigns designed to prevent the development of paralytic disease and interrupt transmission of the ...
Weiner, Joshua A, Connor, Ruth I, Bandyopadhyay, Ananda S, Wright, Peter F, Brickley, Elizabeth B, Wieland-Alter, Wendy F, Ackerman, Margaret E, Modlin, John F   +7 more
core   +1 more source

Promising opportunities to improve polio vaccines

Биопрепараты: Профилактика, диагностика, лечение, 2022
Polioviruses belong to Enterovirus C species and cause severe lesions of the nervous system. In the post-polio eradication era, the World Health Organisation recommends inactivated polio vaccines for effective long-term protection of the population.
E. E. Evreinova, L. M. Khantimirova, V. A. Shevtsov, V. A. Merkulov, V. P. Bondarev   +4 more
doaj   +1 more source

Immune predictors of oral poliovirus vaccine immunogenicity among infants in south India [PDF]

, 2020
Identification of the causes of poor oral vaccine immunogenicity in low-income countries might lead to more effective vaccines. We measured mucosal and systemic immune parameters at the time of vaccination with oral poliovirus vaccine (OPV) in 292 Indian
Grassly, Nicholas
core   +1 more source

Complexity of options related to restarting oral poliovirus vaccine (OPV) in national immunization programs after OPV cessation [version 1; peer review: 1 approved, 2 approved with reservations]

Gates Open Research, 2023
Background: The polio eradication endgame continues to increase in complexity.  With polio cases caused by wild poliovirus type 1 and circulating vaccine-derived polioviruses of all three types (1, 2 and 3) reported in 2022, the number, formulation, and ...
Steven GF Wassilak, Dominika A Kalkowska, Concepcion F Estivariz, Eric Wiesen, Kimberly M Thompson, Cara C Burns, Kamran Badizadegan   +6 more
doaj   +1 more source

Reactivation of a Bacillus Calmette-Guérin Scar Following Routine Infant Vaccination. [PDF]

Clin Case Rep
ABSTRACT A 4‐month‐old infant developed erythema and induration at a Bacillus Calmette–Guérin (BCG) scar shortly after routine DTaP‐IPV‐Hib and pneumococcal vaccination. Laboratory findings were normal, and the lesion resolved spontaneously without treatment.
Demircioğlu F, Demircioğlu AS.
europepmc   +2 more sources

Codon pair bias and viral vaccine design [PDF]

, 2015
The authors acknowledge the long term support of the Wellcome Trust and the Biotechnology and Biological Sciences Research Council.Live attenuated vaccines (LAVs) have prevented morbidity and mortality against a number of important viral diseases (such ...
Tulloch, Fiona Ashley, Ryan, Martin Denis, Pathania, Uday Singh, Luke, Garry Alec   +3 more
core   +1 more source