Results 21 to 30 of about 218,086 (209)

Development of Streptococcus pneumoniae Vaccines Using Live Vectors [PDF]

, 2015
: Streptococcus pneumoniae still causes severe morbidity and mortality worldwide, especially in young children and the elderly. Much effort has been dedicated to developing protein-based universal vaccines to conquer the current shortcomings of capsular ...

core   +1 more source

Problems of poliomyelitis eradication [PDF]

Терапевтический архив
The article is devoted to the problems of implementation of the WHO Global Polio Eradication Initiative. The influence of the features of poliovirus infection and poliovirus vaccines on the course of the program, its successes and difficulties is ...
Olga E. Ivanova, Yulia M. Mikhailova, Liubov I. Kozlovskaya, Viktor V. Maleev   +3 more
doaj   +1 more source

Multiplex PCR-Based Neutralization (MPBN) Assay for Titers Determination of the Three Types of Anti-Poliovirus Neutralizing-Antibodies

Vaccines, 2020
Determination of poliovirus-neutralizing antibodies is an important part of clinical studies of poliovirus vaccines, epidemiological surveillance and seroprevalence studies that are crucial for global polio eradication campaigns.
Hasmik Manukyan, Svetlana Petrovskaya, Konstantin Chumakov, Majid Laassri   +3 more
doaj   +1 more source

Protecting investments in polio eradication: the past, present and future of surveillance for acute flaccid paralysis. [PDF]

, 2004
In September 2003 a WHO consultation group on vaccine-derived polioviruses (VDPV) concluded that in order to prevent future generations of paralytic polio after interruption of transmission of wild poliovirus, the use of trivalent oral polio vaccine (OPV)
D. L. HEYMANN, E. M. DE GOURVILLE, Heymann, DL, R. B. AYLWARD, Aylward, RB, De Gourville, EM   +5 more
core   +1 more source

Microneedle patch as a new platform to effectively deliver inactivated polio vaccine and inactivated rotavirus vaccine

npj Vaccines, 2022
We recently reported a lack of interference between inactivated rotavirus vaccine (IRV) and inactivated poliovirus vaccine (IPV) and their potential dose sparing when the two vaccines were administered intramuscularly either in combination or standalone ...
Sung-Sil Moon, Marly Richter-Roche, Theresa K. Resch, Yuhuan Wang, Kimberly R. Foytich, Houping Wang, Bernardo A. Mainou, Winston Pewin, Jeongwoo Lee, Sebastien Henry, Devin V. McAllister, Baoming Jiang   +11 more
doaj   +1 more source

Immunity levels to poliovirus in Lao children and adults before the vaccine-derived poliovirus outbreak: A retrospective study [PDF]

, 2018
In 2015, several provinces in Lao People's Democratic Republic (Lao PDR) experienced a vaccine-derived poliovirus outbreak. This survey was conducted (i) to evaluate the vaccination coverage in different settings and cohorts using the seroprevalence of ...
Nouanthong, Phonethipsavanh, Nanthavong, Naphavanh, Samountry, Bounthome, Xeuatvongsa, Anonh, Sayasinh, Kong, Jutavijittum, Prapan, Khampanisong, Phonepaseuth, Hübschen, Judith M, Black, Antony P., Diedrich, Sabine, Pauly, Maude, Muller, Claude P.   +11 more
core   +1 more source

Does IPV Boost Intestinal Immunity among Children under Five Years of Age? An Experience from Pakistan

Vaccines, 2023
The oral poliovirus vaccine (OPV) has been the mainstay of polio eradication, especially in low-income countries, and its use has eliminated wild poliovirus type 2.
Muhammad Atif Habib, Sajid Bashir Soofi, Imtiaz Hussain, Imran Ahmed, Zamir Hussain, Rehman Tahir, Saeed Anwar, Simon Cousens, Zulfiqar A. Bhutta   +8 more
doaj   +1 more source

Advax-CpG Adjuvant Provides Antigen Dose-Sparing and Enhanced Immunogenicity for Inactivated Poliomyelitis Virus Vaccines

, 2021
Global immunization campaigns have resulted in a major decline in the global incidence of polio cases, with wild-type poliovirus remaining endemic in only two countries.
Nikolai Petrovsky, Jeremy Baldwin, Yoshikazu Honda-Okubo   +2 more
core   +1 more source

Development of novel inactivated poliovirus vaccines: Breaking away from convention [PDF]

, 2015
Infection with poliovirus (a small, non-enveloped Picornavirus) can result in poliomyelitis, hallmarked by symptoms of paralysis which is caused by viral destruction of motor neurons.
Sanders, B.P.
core   +18 more sources

Effects of maternal antibodies in infants on the immunogenicity and safety of inactivated polio vaccine in infants

Human Vaccines & Immunotherapeutics, 2022
The presence of maternal poliovirus antibodies may interfere with the immune response to inactivated polio vaccine (IPV), and its influence on the safety of vaccination is not yet understood.
Shuyu Gao, Mingwei Wei, Kai Chu, Jingxin Li, Fengcai Zhu   +4 more
doaj   +1 more source