Results 91 to 100 of about 15,343 (151)

Aberrant expression of polo-like kinase 4 in renal cell carcinoma: Association with clinicopathological characteristics and long-term survival. [PDF]

Oncol Lett, 2022
Jiang W, Zhao Y, Zhang S, Zeng Y, Ma J.
europepmc   +1 more source

Combined Delivery of Temozolomide and siPLK1 Using Targeted Nanoparticles to Enhance Temozolomide Sensitivity in Glioma

International Journal of Nanomedicine, 2020
Hui Shi,1,2,* Shuo Sun,1,* Haoyue Xu,3,* Zongren Zhao,3 Zhengzhong Han,3 Jun Jia,3 Dongmei Wu,4 Jun Lu,4 Hongmei Liu,3,5 Rutong Yu1,3,5 1Clinical Medical College, Nanjing Medical University, Nanjing, People’s Republic of China; 2The Second People ...
Shi H, Sun S, Xu H, Zhao Z, Han Z, Jia J, Wu D, Lu J, Liu H, Yu R   +9 more
doaj  

Targeting PLK1-CBX8-GPX4 axis overcomes BRAF/EGFR inhibitor resistance in BRAFV600E colorectal cancer via ferroptosis

Nature Communications
Metastatic BRAFV600E colorectal cancer (CRC) confers poor prognosis and represents a therapeutic bottleneck. To identify resistance mechanisms of the mitogen-activated protein kinase (MAPK) pathway in BRAFV600E CRC, we perform genome-wide CRISPR-Cas9 ...
Zhan Zhao, Jiashuai He, Shenghui Qiu, Lu Wang, Shuchen Huangfu, Yangzhi Hu, Qing Wu, Yabing Yang, Xiaobo Li, Maohua Huang, Shijin Liu, Hanyang Guan, Zuyang Chen, Xiangwei Zhang, Yiran Zhang, Hui Ding, Xiaoxu Zhao, Guandi Xiao, Yunlong Pan, Tongzheng Liu, Yanping Wu, Jinghua Pan   +21 more
doaj   +1 more source

Polo-like kinase 4 is associated with advanced TNM stages and reduced survival and its inhibition improves chemosensitivity in colorectal cancer. [PDF]

Oncol Lett, 2022
Duan Z, Cai L, Cao J, Wu W.
europepmc   +1 more source

Hypoxia Drives Centrosome Amplification in Cancer Cells via HIF1α-dependent Induction of Polo-Like Kinase 4. [PDF]

Mol Cancer Res, 2022
Mittal K, Kaur J, Sharma S, Sharma N, Wei G, Choudhary I, Imhansi-Jacob P, Maganti N, Pawar S, Rida P, Toss MS, Aleskandarany M, Janssen EA, Søiland H, Gupta MV, Reid MD, Rakha EA, Aneja R.   +17 more
europepmc   +1 more source

Polo-like Kinase 4: the Variation During Therapy and its Relation to Treatment Response and Prognostic Risk Stratification in Childhood Acute Lymphoblastic Leukemia Patients. [PDF]

J Pediatr Hematol Oncol, 2023
Xu J, Zhao L.
europepmc   +1 more source

Poster Sessions

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

Publication Only

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

Distinct pathophysiological mechanisms of CEP152 variants in microcephaly and brain abnormalities

EMBO Molecular Medicine
CEP152 is essential for centriole function and neurodevelopment, and pathogenic recessive variants in CEP152 cause primary microcephaly. We identified new compound heterozygous CEP152 variants, c.314 G > A,p.(W105*) and c.2689 A > T,p.(K897*), in a ...
Nanako Hamada, Lama AlAbdi, Tomoko Uehara, Looprasertkul Sasikarn, Takuma Nishijo, Reut Suliman-Lavie, Mais O Hashem, Majid Alfadhel, Shatha Alhefdhi, Brahim Tabarki, Malak Alghamdi, Ikuko Iwamoto, Toshiki Takenouchi, Kenjiro Kosaki, Sagiv Shifman, Seiji Mizuno, Nobuhiko Ohno, Fowzan S Alkuraya, Koh-ichi Nagata   +18 more
doaj   +1 more source

ePoster

European Journal of Neurology, Volume 33, Issue S1, June 2026.
wiley   +1 more source