Results 81 to 90 of about 7,599 (172)

Poster Sessions

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

Inhibitors targeting CDK4/6, PARP and PI3K in breast cancer: a review

Therapeutic Advances in Medical Oncology, 2018
Breast cancer is the global leading cause of cancer-related death in women and it represents a major health burden worldwide. One of the promising breast cancer therapeutic avenues is through small molecule inhibitors (SMIs) which have undergone rapid ...
Siti Muhamad Nur Husna, Hern-Tze Tina Tan, Rohimah Mohamud, Anne Dyhl-Polk, Kah Keng Wong   +4 more
doaj   +1 more source

Tumor treating fields combined with a poly (adenosine diphosphate-ribose) polymerase inhibitor during radiotherapy for rapidly progressing IDH-wildtype diffuse astrocytoma: a case report. [PDF]

J Int Med Res, 2021
Wang Z, Ren Y, Du F, Sun Y, Jiang W.
europepmc   +1 more source

Complete response to olaparib in a patient with metastatic pancreatic cancer harboring a germline BRCA2 mutation

Oncology in Clinical Practice
Metastatic pancreatic cancer (mPC) is usually diagnosed at an advanced stage, and systemic therapy is still the main treatment option. Pathological germline mutations in the BRCA1 or BRCA2 genes are present in aroun 4–7% of cases of pancreatic cancer (PC)
Agata I. Adamczuk-Nurzyńska, Paweł Nurzyński, Artur Sankowski   +2 more
doaj   +1 more source

Poly(adenosine diphosphate ribose) Synthesis in Soluble Extracts of Animal Organs

Journal of Biological Chemistry, 1972
Abstract Poly(adenosine diphosphate ribose) (poly(ADP-ribose)) which is normally synthesized in chromatin is also synthesized from NAD by soluble extracts of animal organs prepared in 0.5 m NaCl, KCl, or NH4Cl. Extracts of thymus, bone marrow, lymph nodes, and spleen are the most active.
openaire   +2 more sources

Patient cost sharing during poly(adenosine diphosphate-ribose) polymerase inhibitor treatment in ovarian cancer. [PDF]

Am J Obstet Gynecol, 2021
Harrison RF, Fu S, Sun CC, Zhao H, Lu KH, Giordano SH, Meyer LA.   +6 more
europepmc   +1 more source

Studies on Poly (Adenosine Diphosphate Ribose)

Journal of Biological Chemistry, 1970
Hirotaka Matsubara, Shuji Hasegawa, Shinji Fujimura, Teruo Shima, Takashi Sugimura, Masamitsu Futai   +5 more
openaire   +1 more source

PARP (Poly ADP‐ribose Polymerase) Family in Health and Disease

MedComm
The poly(ADP‐ribose) polymerase (PARP) family consists of 17 members of nicotinamide adenine dinucleotide (NAD⁺)‐dependent enzymes that regulate key biological processes by catalyzing adenosine diphosphate (ADP)‐ribosylation, either poly(ADP‐ribosyl ...
Pengyuan Lei, Wenfeng Li, Jinhua Luo, Nanxin Xu, Yahe Wang, Dafei Xie, Hua Guan, Bo Huang, Xin Huang, Pingkun Zhou   +9 more
doaj   +1 more source

Adenosine diphosphate-ribosylation greatly affects proteins function: a focus on neurodegenerative diseases

Frontiers in Aging Neuroscience
Adenosine diphosphate-ribosylation (ADPRylation) is a reversible posttranslational modification that plays a crucial role in cellular homeostasis and disease development.
Chaowen Huang, Huilin Xiao, Yang Yang, Jiankun Luo, Yixi Lai, Shizhen Liu, Kanmin Mao, Jialong Chen, Liling Wang   +8 more
doaj   +1 more source

Studies on Poly Adenosine Diphosphate-Ribose

Journal of Biological Chemistry, 1969
Teruo Shima, Shinji Fujimura, Shuji Hasegawa, Yoshiko Shimizu, Takashi Sugimura   +4 more
openaire   +1 more source