Results 171 to 180 of about 9,107 (249)

[Poly(ADP-ribose) polymerases-1 inhibitor MRL-45696 alleviates DNA damage after myocardial ischemia-reperfusion in diabetic rats]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao, 2018
Ji Z, Zeng L, Cheng Y, Liang G.
europepmc   +1 more source

Treatment patterns and clinical outcomes in real‐world patients with small‐cell lung cancer in South Korea: A single‐center experience

International Journal of Cancer, Volume 159, Issue 3, Page 719-728, 1 August 2026.
What's New? The emerging role of immunotherapy in small‐cell lung cancer treatment has not been fully elucidated, particularly outside of clinical trials. This single‐center retrospective cohort study examined real‐world treatment patterns and overall survival in South Korea during the 2018–2023 period.
Sehhoon Park, Danbee Kang, Jin Lee, Hyun Ae Jung, Jong‐Mu Sun, Se‐Hoon Lee, Jin Seok Ahn, Hojoon Lee, Hyuna Lim, Xerxes Pundole, Juhee Cho, Myung‐Ju Ahn   +11 more
wiley   +1 more source

Roles of ADP-Ribosyltransferases in Cancer. [PDF]

Oncol Res
Veilleux M, Nguyen A, Cao C, Shi Y.
europepmc   +1 more source

Beyond Tradition: An Integrated Toxicological, Ecological, and Public Health Perspective on Aristolochic Acids

Journal of Applied Toxicology, Volume 46, Issue 8, Page 2599-2622, August 2026.
ABSTRACT Aristolochia species have long been used in traditional medicine for their presumed anti‐inflammatory, analgesic and antimicrobial properties. However, extensive toxicological and epidemiological evidence now demonstrates that these plants contain aristolochic acids (AAs) I and II, highly potent nephrotoxic, genotoxic, and carcinogenic ...
Victor Ventura de Souza, Lara Rodrigues De Andrade, Tatiana da Silva Souza   +2 more
wiley   +1 more source

Novel <i>ADPRS</i> Missense Variant (p.Leu162Pro) Causes Stress-Induced Childhood-Onset Neurodegeneration With Ataxia and Seizures. [PDF]

Neurol Genet
de Mattos PD, de Moura RD, Bertolino MF, Valente PF, Matos IA, Caldas VM, Lobao Cunha PE, Kok F, Hoch NC.   +8 more
europepmc   +1 more source

Goniothalamin as a Styryl‐Lactone Toxicophore in Cancer Models: Electrophile‐Driven DNA Damage, Reactive Oxygen Species–Endoplasmic Reticulum Stress Signaling and Detoxification‐Relevant Safety Considerations

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
Goniothalamin (GTN) exerts anticancer effects by promoting reactive oxygen species (ROS) generation, glutathione (GSH) depletion, DNA damage, endoplasmic reticulum (ER) stress, and mitochondrial dysfunction. These interconnected events trigger apoptosis, necroptosis, anoikis, and autophagy, while modulating mitogen‐activated protein kinase (MAPK ...
Nataša Joković, Strahinja Pešić, Marija Novaković, Anđela Dubroja Krstić, William N. Setzer, Javad Sharifi‐Rad, Daniela Calina   +6 more
wiley   +1 more source

Understanding single stranded DNA gaps: from formation to fate. [PDF]

Biochem J
Garg S, Moldovan GL.
europepmc   +1 more source

Genetic Counseling in Aotearoa New Zealand: Context, Practice and the Future of Genomic Healthcare

Journal of Genetic Counseling, Volume 35, Issue 4, August 2026.
ABSTRACT Genetic counselors have been practicing in Aotearoa New Zealand since 1995, and are now established across both public and private sectors of healthcare. While significant global efforts have been made to define the profession of genetic counseling, the distinct way in which genetic counselors practice in New Zealand has not been formally ...
Elisha Swainson, Harry G. Fraser, Linda L. Cheng, Sarah Collis, Alice Christian, Kimberley Gamet, Alison McEwen   +6 more
wiley   +1 more source

The Expanding Landscape of ADP-Ribosylation: Protein, DNA, RNA, and Mitochondrial Regulation. [PDF]

Chem Res Toxicol
Sin YC, Zhao L.
europepmc   +1 more source

SNHG15 Positively Regulates Influenza Virus Infection Through Its Association With miR‐153 and RABL2A

Journal of Medical Virology, Volume 98, Issue 8, August 2026.
ABSTRACT Influenza viruses cause seasonal epidemics, and current vaccines do not fully protect against them. This study focuses on long non‐coding RNAs (lncRNAs), which are RNA molecules that do not code for proteins but play crucial roles in various biological processes. We identified 17 lncRNAs altered by the influenza virus.
Samuel Pushparaj, Kishore Vaddadi, Chaoqun Huang, Yurong Liang, Dao Xu, Gayan Bamunuarachchi, Prince Jhandai, Keerthana Santhosh, Elizabeth Varghese, Lin Liu   +9 more
wiley   +1 more source