Results 201 to 210 of about 39,389 (304)
181 CHARACTERIZATION OF POLY(ADP-RIBOSE) POLYMERASE WITH HUMAN AUTOANTIBODIES [PDF]
Hisashi Yamanaka +2 more
openalex +1 more source
Anticancer Molecular Mechanisms of Phytosterols: An Updated Review on Clinical Trials
Phytosterols, a form of naturally occurring substance structurally related to cholesterol, have been getting considerable interest due to their possible anticancer properties. Phytosterols induce apoptosis, block the cell cycle, and abrogate the invasion and metastasis of cancer cells, offering a multi‐manifestation treatment of cancer.
Muhammad Shahbaz +14 more
wiley +1 more source
Natural Products in Cancer Prevention and Therapy: Current Challenges and Future Directions
Natural products play a pivotal role in cancer therapy. They induce cancer cell death by reprogramming four metabolic pathways while precisely targeting the tumor microenvironment and immune cells. These compounds not only leverage novel delivery systems for innovative applications but also demonstrate unique therapeutic efficacy across clinical stages:
Ruimiao Qian +8 more
wiley +1 more source
Poly(ADP-ribose) polymerase enzymes and the maintenance of genome integrity
T. Eisemann, J. Pascal
semanticscholar +1 more source
Ventilator‐Induced Lung Injury: Mechanotransduction and Potential Therapeutic Targets
Mechanical ventilation (MV) is expected to undergo significant transformative advancements by 2050, with the emergence of personalized ventilation systems that promise to revolutionize respiratory care. However, the risk of ventilator‐induced lung injury (VILI) remains a significant concern at this stage and VILI still exists at that time.
He Ren +4 more
wiley +1 more source
Oxidative stress-induced, poly(ADP-ribose) polymerase-dependent upregulation of ET-1 expression in chronic diabetic complicationsThis article is one of a selection of papers published in the special issue (part 1 of 2) on Forefronts in Endothelin. [PDF]
Jane Chiu +4 more
openalex +1 more source
This systematic review and meta‐analysis (100 trials, 9192 patients) clarifies breast cancer ICI‐based combination toxicity hierarchies. ICI‐ADC has higher grade ≥ 3 TRAEs; ICI‐mTKI has the worst irAEs, while ICI‐PARPi/HER2‐targeted combinations present the lowest risks.
Yunwei Lu +4 more
wiley +1 more source

