Results 211 to 220 of about 39,389 (304)

Automodified Poly(ADP-Ribose) Polymerase Analysisto Monitor DNA Damagein Peripheral Lymphocytes of Floriculturists Occupationally Exposed to Pesticides [PDF]

, 2019
S Imperato, Carmela Mistretta, Maria Marone, Ilaria Migliaccio, Ilaria Pulcinelli, Maria Rosaria Faraone Mennella   +5 more
openalex   +1 more source

Regulation of R‐Loop Dynamics by Proteins and Long Noncoding RNAs: An Emerging Paradigm for Cancer Treatment

Cancer Science, Volume 117, Issue 2, Page 297-307, February 2026.
R‐loops are three‐stranded nucleic acid structures whose dysregulation leads to genomic instability and cancer progression. This review summarizes the protein and lncRNA machineries that regulate R‐loop dynamics and discusses the therapeutic potential of targeting these pathways in cancer.
Miho M. Suzuki, Keiko Shinjo, Tatsunori Nishimura, Yutaka Kondo   +3 more
wiley   +1 more source

[Role of poly(ADP-ribose) polymerases-1-mediated blockade of autophagy in ischemia/reperfusion injury of rat cardiomyocytes]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao, 2018
Zhao W, Wang Y, Wei G, Xu S.
europepmc   +1 more source

Alternative mechanisms of inhibiting activity of poly ADP-ribose polymerase-1 [PDF]

, 2016
Chandra Shaker Sriram
openalex   +1 more source

Denosumab Regulates Titanium Particles‐Induced Macrophages Inflammation and Osteolysis by Targeting the ST18/PARP1 Interaction

Orthopaedic Surgery, Volume 18, Issue 2, Page 322-334, February 2026.
The schematic diagram of the role of Denosumab and ST18/PARP1 axis in the prevention of prosthesis‐related AL. Denosumab regulates TiPs‐induced macrophage activation and osteolysis through the NF‐κB pathway and M1 polarization, with ST18 acting as a key mediator.
Zhipeng Chen, Fan Yang, Yifan Yu, Junxi Chen, Jichao Ye, Yue Ding   +5 more
wiley   +1 more source

Epigenomics‐guided precision oncology: Chromatin variants in prostate tumor evolution

International Journal of Cancer, Volume 158, Issue 2, Page 314-332, 15 January 2026.
Abstract Prostate cancer is a common malignancy that in 5%–30% leads to treatment‐resistant and highly aggressive disease. Metastasis‐potential and treatment‐resistance is thought to rely on increased plasticity of the cancer cells—a mechanism whereby cancer cells alter their identity to adapt to changing environments or therapeutic pressures to create
Kira Furlano, Tina Keshavarzian, Nadine Biernath, Annika Fendler, Maria de Santis, Joachim Weischenfeldt, Mathieu Lupien   +6 more
wiley   +1 more source

Review of poly (ADP-ribose) polymerase (PARP) mechanisms of action and rationale for targeting in cancer and other diseases.

Critical Reviews in Eukaryotic Gene Expression, 2014
J. Morales, Longshan Li, Farjana J Fattah, Ying Dong, E. Bey, Malina Patel, Jinming Gao, D. Boothman   +7 more
semanticscholar   +1 more source

The effects of organic solvents on poly(ADP-ribose) polymerase-1 activity: implications for neurotoxicity

, 2004
Marek Banasik, Todd Stedeford, Robert P. Strosznajder, Amanda S. Persad, Seigo Tanaka, Kunihiro Ueda   +5 more
openalex   +2 more sources

Activator-Induced Spread of Poly(ADP-Ribose) Polymerase Promotes Nucleosome Loss at Hsp70 [PDF]

, 2011
Steven J. Petesch, John T. Lis
openalex   +1 more source

Interplay between ubiquitination and ADP-ribosylation and the case of dual modification ADPr-Ub. [PDF]

Essays Biochem
Zhu K, Chatrin C, Smith R, Ahel D, Ahel I.   +4 more
europepmc   +1 more source