Results 111 to 120 of about 1,124 (169)
Poly(ADP-ribosyl)ation as a new posttranslational modification of YB-1
, 2015 International audienceMultifunctional Y-box binding protein 1 (YB-1) is actively studied as one of the components of cellular response to genotoxic stress. However, the precise role of YB-1 in the process of DNA repair is still obscure.
Lavrik, Olga +8 more
core +1 more source
Physiology and pathophysiology of poly(ADP-ribosyl)ation
One of the immediate eukaryotic cellular responses to DNA breakage is the covalent post-translational modification of nuclear proteins with poly(ADP-ribose) from NAD+ as precursor, mostly catalysed by poly(ADP-ribose) polymerase-1 (PARP-1).
Burkle A
core
L-Selegiline Potentiates the Cellular Poly(ADP-Ribosyl)ation Response to Ionizing Radiation
, 2020 DNA strand breaks induced by alkylating agents, oxidants, or ionizing radiation trigger the covalent modification of nuclear proteins with poly(ADP-ribose), which is catalyzed for the most part by poly(ADP-ribose) polymerase-1 and plays a role in DNA ...
R P, A B, S B, ( C B, R M
core
Toward a Quantitative Analysis of PARP-1 and Poly(ADP-ribosyl)ation in Cellular Senescence
, 2010 Aging is a complicated and multifactorial phenomenon. Model systems involving the induction of replicative senescence in cultured cells have been indispensable in elucidating some of the mechanisms underlying this complex process. An understanding of how
Edmonds, Yvette M.
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Modulation de la structure de la chromatine par la poly(ADP-ribosyl)ation
, 1988 Nous avons caractérisé les protéines chromosomales acceptrices depoly(ADP-ribose) dans différents niveaux d'organisation de la chromatine et nous avons étudié l'effet structural de leur poly(ADP-ribosyl)ation sur la structure chromatinienne ...
Huletsky, Ann
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HYPERTHYROIDISM AND POLY(ADP-RIBOSYL)ATION IN RAT TESTIS GERM CELL DIFFERENTIATION.
, 2007 Aim of our research was to study the effect of increased serum levels of thyroid hormone (triiodothyronine, T3) on rat testis spermatogenesis, a system well characterized as it regards morpho-functional and biochemical features, including the poly(ADP ...
DI MEO +7 more
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, 2018 La poly(ADP-ribosyl)ation implique principalement deux enzymes, la poly(ADP-ribose) polymerase-1 (PARP-1) et la poly(ADP-ribose) glycohydrolase (PARG). PARP-1 catalyse la formation de poly(ADP-ribose) à partir du NAD+ lors de bris à l'ADN.
Molloy-Simard, Vanessa
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Analyses biochimique et protéomique de la poly(ADP-ribosyl)ation
, 2018 La poly(ADP-ribosyl)ation est une modification post-traductionnelle qui est stimulée en réponse à des dommages à l'ADN. Les poly(ADP-ribose) polymerases (PARPs) synthétisent des polymères branchés de poly(ADP-ribose) (PAR) qui peuvent se lier de manière ...
Tardif, Maxime
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Modulation de la structure de la chromatine par la poly(ADP-ribosyl)ation
Nous avons caractérisé les protéines chromosomales acceptrices depoly(ADP-ribose) dans différents niveaux d'organisation de la chromatine et nous avons étudié l'effet structural de leur poly(ADP-ribosyl)ation sur la structure chromatinienne. Premièrement,
Huletsky, Ann
core
L-selegiline potentiates the cellular poly(ADP-ribosyl)ation response to ionizing radiation
DNA strand breaks induced by alkylating agents, oxidants, or ionizing radiation trigger the covalent modification of nuclear proteins with poly(ADP-ribose), which is catalyzed for the most part by poly(ADP-ribose) polymerase-1 and plays a role in DNA ...
Brabeck C +5 more
core