Results 111 to 120 of about 6,825 (206)

New perspectives on the plant PARP family: Arabidopsis PARP3 is inactive, and PARP1 exhibits predominant poly (ADP-ribose) polymerase activity in response to DNA damage

open access: yesBMC Plant Biology, 2019
Background Poly (ADP-ribosyl) ation (PARylation) is an important posttranslational modification that regulates DNA repair, gene transcription, stress responses and developmental processes in multicellular organisms.
Zongying Gu   +7 more
doaj   +1 more source

PARP1 allows proper telomere replication through TRF1 poly (ADP-ribosyl)ation and helicase recruitment. [PDF]

open access: yesCommun Biol, 2023
Maresca C   +12 more
europepmc   +1 more source

Potential biological role of poly (ADP-ribose) polymerase (PARP) in male gametes [PDF]

open access: yes, 2009
Maintaining the integrity of sperm DNA is vital to reproduction and male fertility. Sperm contain a number of molecules and pathways for the repair of base excision, base mismatches and DNA strand breaks.
Ashok Agarwal   +235 more
core   +1 more source

Inhibition of GSDMD Activates Poly(ADP-ribosyl)ation and Promotes Myocardial Ischemia-Reperfusion Injury. [PDF]

open access: yesOxid Med Cell Longev, 2022
Zhang ZH   +15 more
europepmc   +1 more source

Tankyrase Regulates Neurite Outgrowth through Poly(ADP-ribosyl)ation-Dependent Activation of β-Catenin Signaling. [PDF]

open access: yesInt J Mol Sci, 2022
Mashimo M   +11 more
europepmc   +1 more source

NAD+ sensing by PARP7 regulates the C/EBPβ-dependent transcription program during adipogenesis

open access: yesCell Reports
Summary: We identified poly(ADP-ribose) polymerase 7 (PARP7), a mono(ADP-ribosyl) transferase, as a regulator of C/EBPβ-dependent proadipogenic gene expression.
MiKayla S. Stokes   +13 more
doaj   +1 more source

The poly(ADP-ribosyl)ation of BRD4 mediated by PARP1 promoted pathological cardiac hypertrophy. [PDF]

open access: yesActa Pharm Sin B, 2021
Li Z   +8 more
europepmc   +1 more source

PARG Mutation Uncovers Critical Structural Determinant for Poly(ADP-Ribose) Hydrolysis and Chromatin Regulation in Embryonic Stem Cells

open access: yesCells
Poly(ADP-ribosyl)ation is a crucial posttranslational modification that governs gene expression, chromatin remodeling, and cellular homeostasis. This dynamic process is mediated by the opposing activities of poly(ADP-ribose) polymerases (PARPs), which ...
Yaroslava Karpova   +3 more
doaj   +1 more source

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