Results 111 to 120 of about 973,687 (259)

Elevated CO

Scientia Horticulturae
Orobanche infection is a major constraint to tomato production because the parasite acts as a strong physiological and nutritional sink, impairing host growth, photosynthesis, and metabolism.
Manal F. El-Khadragy, Hana Sonbol, Shereen Magdy Korany, María Gabriela Maridueña-Zavala, Mariam Abdulaziz Alkhateeb, Marcelo Carvalho Minhoto Teixeira Filho, Maha H. Khalaf, Mahmoud M.Y. Madany   +7 more
doaj   +1 more source

Antiparasitic Drug Discovery for the Polyamine Pathway

, 2011
Diseases caused by parasitic organisms are a significant component of global morbidity and represent a serious challenge for drug discovery and development.
Mary Morada, Nigel Yarlett
core   +1 more source

From knowledge to action: the importance of characterizing herbicide resistance mechanisms for implementing management strategies

Pest Management Science, EarlyView.
This review bridges the gap between understanding resistance mechanisms and applying them in weed management, highlighting how mechanistic insights reveal vulnerabilities that can guide more effective control strategies. Abstract Herbicide resistance remains one of the most intensively studied areas in weed science because of its direct consequences ...
Luan Cutti, Eric L. Patterson, Todd A. Gaines, Aldo Merotto   +3 more
wiley   +1 more source

Proteo‐transcriptomic insights into the venom composition of the ectoparasitoid Eupelmus urozonus

Pest Management Science, EarlyView.
Integrated venom‐gland transcriptomics and venom proteomics of Eupelmus urozonus identified 316 venom proteins, including 75 secreted candidates, revealing diverse hydrolases, proteases/inhibitors and many uncharacterized effectors. Abstract BACKGROUND Ectoparasitoid venoms are ‘cocktails’ of bioactive molecules injected during oviposition to paralyze ...
Federica De Stefano, Carmen Scieuzo, Rosanna Salvia, Riccardo Moretti, Flora Cozzolino, Maria Monti, Heiko Vogel, Patrizia Falabella   +7 more
wiley   +1 more source

Catechins and Their Effect on the Gut Microbiome in Health and Cancer

Phytotherapy Research, EarlyView.
ABSTRACT Catechins are a group of flavonoids found primarily in green tea, fruits, and berries; they play a significant role in the modulation of the gut microbiota, thereby having an impact on gut health and cancer prevention. Owing to their low bioavailability, catechins are transformed by the gut microbiota into various bioactive metabolites such as
Prakash Monika, Bindu Sadanandan, Honnamachanahalli Ramachandraiah Tejashree, Maitreyi Darbha, Kirti Gupta, Srinivas Reneeka   +5 more
wiley   +1 more source

Carbon dots as a smart nanoplatform for the blood‐brain barrier penetration and ischemic stroke therapy

Responsive Materials, EarlyView.
This review presents the structure and transport routes of the blood‐brain barrier, summarizes the ischemic stroke pathophysiological cascade, and discusses the BBB‐crossing mechanisms and multitarget therapeutic effects of carbon dots, demonstrating their promising theranostic potential for ischemic stroke.
Yanhan Huang, Xuan Hou, Haiping Zhao, Qi Kong, Xiayan Wang, Xiaokun Geng, Zaicheng Sun   +6 more
wiley   +1 more source

Dysregulation of SIRT1, polyamines and miRNA editing in cancer and aging

Amino Acids
Interest in RNA editing has emerged in molecular medicine due to its widespread dysregulation and therapeutic potential. Its regulatory mechanisms in governing non-coding RNAs, especially microRNAs (miRNAs) remain largely unresolved. Emerging evidence in
Miora Bruna Marielle Ramamonjiharisoa, Sen Liu   +1 more
doaj   +1 more source

Exposure to Structurally Related Organophosphate Esters Elicits Distinct Metabolomic Perturbations in Daphnia magna

Environmental Toxicology, EarlyView.
ABSTRACT Organophosphate esters (OPEs) are found ubiquitously in the environment and exposure to these chemicals has induced behavioral, developmental, and morphological impairments in several model organisms. Yet there is still a lack of understanding of how sub‐lethal exposure disrupts organism function at the molecular‐level, especially for Daphnia ...
Salwa Hajir, Sanam Yousifie, Karl J. Jobst, André J. Simpson, Myrna J. Simpson   +4 more
wiley   +1 more source

Temporal changes in polyamine, glutathione, and amino acid metabolism during 3T3-L1 preadipocyte differentiation.

, 2016
Time course profiles of metabolites involved in glutathione metabolism (A-C), polyamine metabolism (D-G), and amino acid metabolism (H) over the first 48 h of adipocyte differentiation. Control cells had 0.1% DMSO. (I) Hypothetical scheme linking proline
Gerd Bobe (382976), Jan F. Stevens (561395), Jay S. Kirkwood (561389), Claudia S. Maier (1310910), Cristobal L. Miranda (2305120)   +4 more
core   +1 more source

Opposing Roles for ATP13A2 and ATP13A3 in Breast Cancer Subtype-Specific Polyamine Homeostasis

Biomolecules
Polyamine homeostasis is essential for normal cellular function and is maintained through coordinated regulation of polyamine biosynthesis, catabolism, and transport.
Emily Meeus, Jan Eggermont, Sarah van Veen, Peter Vangheluwe   +3 more
doaj   +1 more source