Results 101 to 110 of about 1,489,782 (254)

Discriminating Between Living and Dead Bacteria With a Field‐Effect Transistor Based on Nano‐Channels

Small, EarlyView.
Bacterial viability is determined in a complex environment with a field‐effect biological transistor with a limit of detection of a single bacterium. Living, antibiotic‐treated, thermally denatured, and inhibited E. coli generate distinct electrical signatures, enabling label‐free single‐cell detection and providing new opportunities for rapid ...
Bar Chen, Vijay Garika, Shubham Babbar, Pooja Verma, Tom Cohen, Kfir Kattav, Fanny Akselrod, Aparnaa Shree Vijaikumar, Shankar Bhattarai, Sherina Harilal, Evgeny Pikhay, Inna Shechter, Doron Greental, Muhammad Y. Bashouti, Izhar Ron, Yakov Roizin, Barak Akabayov, Gil Shalev   +17 more
wiley   +1 more source

Exposure to Structurally Related Organophosphate Esters Elicits Distinct Metabolomic Perturbations in Daphnia magna

Environmental Toxicology, EarlyView.
ABSTRACT Organophosphate esters (OPEs) are found ubiquitously in the environment and exposure to these chemicals has induced behavioral, developmental, and morphological impairments in several model organisms. Yet there is still a lack of understanding of how sub‐lethal exposure disrupts organism function at the molecular‐level, especially for Daphnia ...
Salwa Hajir, Sanam Yousifie, Karl J. Jobst, André J. Simpson, Myrna J. Simpson   +4 more
wiley   +1 more source

Nonthermal plasma approaches for combating implant‐associated infections: A compendious review

VIEW, EarlyView.
Implant‐associated infections pose serious clinical challenges. Non‐thermal plasma (NTP) modifications overcome this bottleneck in distinct ways relative to traditional sterilization methods. Gas‐phase plasmas generate highly energetic species, UV radiation and reactive oxygen/nitrogen species (RONS), which alter the implant surface properties.
A. M. Trimukhe, Satish Rojekar, Amol Gholap, K. Navaneetha Pandiyaraj, Mukesh Patekar, Claudia Riccardi, R. R. Deshmukh, Tomáš Kovářík, Kalim Deshmukh   +8 more
wiley   +1 more source

Polyamine Metabolism in Disease and Polyamine-Targeted Therapies [PDF]

, 2019
Polyamines are ubiquitous polycations essential for all cellular life. The most common polyamines in eukaryotes, spermine, spermidine, and putrescine, exist in millimolar intracellular concentrations that are tightly regulated through biosynthesis, catabolism, and transport.
openaire   +3 more sources

Diet–Microbiome–Immune Interactions at the Gut Mucosa in Food Allergy: Mechanisms, Gaps, and Therapeutic Implications

Allergy, EarlyView.
ABSTRACT Mucosal surfaces are sites of highly dynamic interactions among epithelial and immune cells, environmental exposures, particularly dietary inputs, and the diverse microbial communities and their metabolites. These elements continually influence each other to maintain homeostasis and ensure appropriate immune discrimination between pathogens ...
Clara Delaroque, Liam O'Mahony, Inge Kortekaas Krohn, Charlotte G. Mortz, Markus Ollert, Mahesh S. Desai   +5 more
wiley   +1 more source

Integrative analysis of polyamine-associated genes reveals a prognostic and immunological signature in esophageal squamous cell carcinoma

Discover Oncology
Esophageal squamous cell carcinoma (ESCA) is a highly aggressive malignancy with substantial heterogeneity and poor prognosis. Polyamine metabolism has been implicated in tumor progression and immune regulation, yet its specific role in ESCA remains ...
Xiuli Cao, Yuanyuan Chen, Tao Li, Jinxing Wei   +3 more
doaj   +1 more source

Polyamine Metabolism in Flax in Response to Treatment with Pathogenic and Non-pathogenic Fusarium Strains

Frontiers in Plant Science, 2015
Flax crop yield is limited by various environmental factors, but the largest crop losses worldwide are caused by Fusarium infection. Polyamines are one of the many metabolites possibly involved in the plant response to infection.
Wioleta eWojtasik, Anna eKulma, Katarzyna eNamysł, Marta ePreisner, Jan eSzopa   +4 more
doaj   +1 more source

Lysine harvesting is an antioxidant strategy and triggers underground polyamine metabolism

Nature, 2019
Both single and multicellular organisms depend on anti-stress mechanisms that enable them to deal with sudden changes in the environment, including exposure to heat and oxidants.
V. Olin-Sandoval, Jason S. L. Yu, L. Miller-Fleming, M. Alam, Stephan Kamrad, C. Correia-Melo, R. Haas, Joanna Segal, David Alejandro Peña Navarro, Lucía Herrera-Dominguez, Oscar Méndez-Lucio, J. Vowinckel, M. Mülleder, M. Ralser   +13 more
semanticscholar   +1 more source

Maternal Perinatal Gut Microbiome Is Shaped by Traditional Farming Lifestyle and Associated With Early Childhood Atopic Disease

Allergy, EarlyView.
We assessed whether the maternal perinatal gut microbiome and serum SCFA and cord blood SCFA differ between traditional farming and urban dyads. Women following a farming lifestyle had increased microbial diversity, several differentially abundant bacterial species and functional pathways, and increased circulating SCFA. Overall maternal gut microbiome
Erin C. Davis, Courtney M. Jackson, Nichole S. Diaz, Jazmine Susana, Ashley Nelson, Richard Insel, Antti E. Seppo, Kirsi M. Järvinen   +7 more
wiley   +1 more source

Essential, deadly, enigmatic: Polyamine metabolism and roles in fungal cells

Fungal Biology Reviews, 2019
Polyamines are essential metabolites found in all organisms. Intracellular polyamine levels are tightly maintained by biosynthesis, degradation, uptake and excretion processes that involve regulatory mechanisms – such as the antizyme inhibitory protein –
R. O. Rocha, R. Wilson
semanticscholar   +1 more source