Results 21 to 30 of about 973,687 (259)

Toll-like Receptor Activation Remodels the Polyamine and Tryptophan Metabolism in Porcine Macrophages

Metabolites
Background: The early nutritional metabolism of piglets is intimately associated with the regulation of immune function, and amino acids play a crucial role in modulating the fate and function of porcine immune cells, especially macrophages. However, the
Meimei Zhang, Lingfei Du, Yinhao Shen, Peng Bin   +3 more
doaj   +2 more sources

Mathematical Modeling of Polyamine Metabolism in Mammals [PDF]

Journal of Biological Chemistry, 2006
Polyamines are considered as essential compounds in living cells, since they are involved in cell proliferation, transcription, and translation processes. Furthermore, polyamine homeostasis is necessary to cell survival, and its deregulation is involved in relevant processes, such as cancer and neurodegenerative disorders.
Rodríguez-Caso, Carlos Francisco, Montañez, Raúl, Cascante, Marta, Sánchez-Jiménez, Francisca María, Medina-Torres, Miguel Ángel   +4 more
openaire   +6 more sources

Investigation of Polyamine Metabolism and Homeostasis in Pancreatic Cancers

Medical Sciences, 2017
Pancreatic cancers are currently the fourth leading cause of cancer-related death and new therapies are desperately needed. The most common pancreatic cancer is pancreatic ductal adenocarcinoma (PDAC).
Otto Phanstiel, Chelsea Massaro
exaly   +3 more sources

T_H17-Associated Polyamine Metabolism-Guided Nanozyme Promotes Alveolar Bone Repair in Periodontitis. [PDF]

Adv Sci (Weinh)
A pronounced TH17‐skewed immune response is identified in experimental periodontitis, and enrichment of the polyamine pathway is observed during TH17 differentiation, suggesting its potential as an immunometabolic target. Inspired by these findings, DFMO@Ui‐Mn is developed as a therapeutic platform combining cascade ROS scavenging with immunometabolic ...
Zhu C, Li T, Jin Y, Li Y, Liu Q, Fang R, Qu L, Tang X, Li R, Zhao X, Hao J, Fang B, Xia L.   +12 more
europepmc   +2 more sources

Alterations of renal polyamine metabolism in mice with folic acid-induced chronic kidney disease

Biochemistry and Biophysics Reports
Chronic kidney disease (CKD) often follows acute kidney injury, leading to renal fibrosis and progressive renal failure. Spermine, a polyamine with antioxidant and anti-inflammatory properties, helps reduce renal fibrosis and may serve as a biomarker for
Cheng Xue, Jiaxin Chen, Xinming Li, Chenchen Zhou, Zhiguo Mao   +4 more
doaj   +2 more sources

Light Spectral Composition Modifies Polyamine Metabolism in Young Wheat Plants [PDF]

, 2022
Although light-emitting diode (LED) technology has extended the research on targeted photomorphogenic, physiological, and biochemical responses in plants, there is not enough direct information about how light affects polyamine metabolism. In this study,
Gondor, Orsolya Kinga, Imre Majláth, Tibor Janda, Judit Tajti, Orsolya Kinga Gondor, Rahman, Altafur, Kamirán Áron Hamow, Hamow, Kamirán Áron, Gholizadeh, Fatemeh, Pál, Magda, Tajti, Judit, Janda, Tibor, Szalai, Gabriella, Gabriella Szalai, Ahres, Mohamed, Altafur Rahman, Majláth, Imre, Fatemeh Gholizadeh, Magda Pál, Mohamed Ahres   +19 more
core   +1 more source

Investigation of The Roles of Hydrogen Peroxide and NADPH Oxidase in The Regulation of Polyamine Metabolism in Maize Plants under Drought Stress Conditions

Journal of Agricultural Sciences, 2022
The relationship between hydrogen peroxide and the metabolism of polyamines and the role of NADPH oxidase (NOX) in that relationship under drought conditions remains unclear.
Aykut Sağlam, Mehmet Demiralay, Fuat Yetişsin, Asım Kadıoğlu   +3 more
doaj   +1 more source

Polyamine metabolism and cancer [PDF]

Journal of Cellular and Molecular Medicine, 2003
AbstractPolyamines are aliphatic cations present in all cells. In normal cells, polyamine levels are intricately controlled by biosynthetic and catabolic enzymes. The biosynthetic enzymes are ornithine decarboxylase, S‐adenosylmethionine decarboxylase, spermidine synthase, and spermine synthase.
Thresia, Thomas, T J, Thomas
openaire   +2 more sources

Stress and polyamine metabolism in fungi [PDF]

Frontiers in Chemistry, 2014
Fungi, as well as the rest of living organisms must deal with environmental challenges such as stressful stimuli. Fungi are excellent models to study the general mechanisms of the response to stress, because of their simple, but conserved, signal-transduction and metabolic pathways that are often equivalent to those present in other eukaryotic systems.
Valdés-Santiago, Laura, Ruiz-Herrera, José   +1 more
openaire   +3 more sources

Polyamine Metabolism under Different Light Regimes in Wheat [PDF]

, 2021
Although the relationship between polyamines and photosynthesis has been investigated at several levels, the main aim of this experiment was to test light-intensity-dependent influence of polyamine metabolism with or without exogenous polyamines.
Gondor, Orsolya Kinga, Imre Majláth, Tibor Janda, Orsolya Kinga Gondor, Judit Tajti, Kamirán Áron Hamow, Hamow, Kamirán Áron, Pál, Magda, Tajti, Judit, Janda, Tibor, Szalai, Gabriella, Gabriella Szalai, Majláth, Imre, Magda Pál   +13 more
core   +1 more source