Results 51 to 60 of about 1,186 (173)

From “Monarch, Minister, Assistant, and Envoy” to “Microbial Dialogue”: A Review of Novel Mechanisms by Which Chinese Herb Pairs Improve Metabolic Diseases Through Gut Microbiota Metabolic Regulation

open access: yesGastroenterology Research and Practice, Volume 2026, Issue 1, 2026.
Metabolic diseases, including obesity, Type 2 diabetes, and nonalcoholic fatty liver disease, have become a severe global health burden, and their pathogenesis is closely associated with gut microbiota dysbiosis. As the core unit of traditional Chinese medicine (TCM) compatibility theory, Chinese herb pairs possess unique advantages in metabolic ...
Zeyu Wang, Palash Mandal
wiley   +1 more source

Polygala sabulosa A. W. Bennett: obtenção de estirilpironas e cumarinas, preparo de análogos e ensaios de atividades biológicas [PDF]

open access: yes, 2008
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas. Programa de Pós-Graduação em Química.No presente estudo, realizou-se uma reinvestigação fitoquímica da espécie Polygala sabulosa para a obtenção dos ...
Mendes, Beatriz Garcia
core  

Avaliação do potencial antidepressivo de derivados semissintéticos da escopoletina obtida da Polygala sabulosa [PDF]

open access: yes, 2011
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas.
Vieira, Roberto Ferreira
core  

LGRPv2: A high‐value platform for the advancement of Fabaceae genomics

open access: yesPlant Biotechnology Journal, Volume 23, Issue 9, Page 4057-4075, September 2025.
Summary Fabaceae, as one of the most diverse angiosperm families, plays a crucial role in maintaining global ecosystems and advancing human civilization. With the rapid accumulation of legume genomes, we developed LGRPv2 (https://fabaceae.cgrpoee.top), an updated version of the Legume Genomics Research Platform.
Zijian Yu   +15 more
wiley   +1 more source

Participação das dihidroestiril-2-pironas e estiril-2-pironas nas ações centrais do tipo-benzodiazepínicas da planta Polygala sabulosa A. W. Bennett (Polygalaceae) em roedores [PDF]

open access: yes, 2007
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas.
Duarte, Filipe Silveira
core  

Effect of topical application of two Polygala tenuifolia species decoction on guinea pig skin

open access: yes, 2017
Purpose: To investigate the effect of the topical decoction of Polygala tenuifolia Willd. and Polygala sibirica L. on a guinea pig model of sore and ulcer.Method: A guinea pig model of sore and ulcer was produced by Staphylococcus aureus, and 80 guinea ...
Shi, Jingjing   +5 more
core   +1 more source

Tenuifolin Attenuates Methamphetamine‐Induced Reinstatement in Mice by Regulating Hippocampal Postsynaptic BDNF Signaling

open access: yesCNS Neuroscience &Therapeutics, Volume 31, Issue 8, August 2025.
Tenuifolin attenuates methamphetamine‐induced reinstatement in mice by regulating hippocampal postsynaptic BDNF signaling. Left, The reduction of the expression of BDNF and PSD‐95 levels and abnormal synaptic plasticity promote METH‐induced reinstatement behavior in mice. Right, TEN treatment increases the expression of BDNF and PSD 95 and improves the
Yize Qi   +6 more
wiley   +1 more source

Estudo do efeito anti-inflamatório da Polygala sabulosa A. W. Bennett no modelo de pleurisia induzida por carragenina em camundongos [PDF]

open access: yes, 2015
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Farmácia, Florianópolis, 2015.A planta Polygala sabulosa A.W.
Nascimento, Marcus Vinícius Pereira dos Santos
core  

Senegenin regulates the mechanism of insomnia through the Keap1/Nrf2/PINK1/Parkin pathway mediated by GAD67

open access: yesJournal of Sleep Research, Volume 34, Issue 3, June 2025.
Summary GAD67 impacts insomnia as a key enzyme catalysing the conversion of glutamate (Glu) to gamma‐aminobutyric acid (GABA). Senegenin enhances neuroprotection and is used widely to treat insomnia and other neurological diseases. This study aimed to investigate how senegenin regulates insomnia through a GAD67‐mediated signalling pathway.
Honglin Jia   +7 more
wiley   +1 more source

Tangeretin Improves the Memory of Swiss Mice, Suggesting Potential Molecular Interventions Through Animal Behavior Assessments and In Silico Studies

open access: yesBrain and Behavior, Volume 15, Issue 5, May 2025.
Swiss mice treated with tangeretin showed better performance in marble burying, dust removal, and trained swimming tests, resulting elevation of memory performance, problem‐solving, and motor coordination. The compound also demonstrated a remarkable binding affinity toward the D2 receptor with favorable pharmacokinetic properties in in silico analysis ...
Md. Sakib Al Hasan   +8 more
wiley   +1 more source

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