Results 71 to 80 of about 1,186 (173)

Identification and Expression Analysis of the Terpenoid Synthase Gene Family in Dendrobium nobile

open access: yesJournal of Food Biochemistry, Volume 2025, Issue 1, 2025.
Terpenoid synthase (TPS) is a crucial enzyme catalyzing terpenoid synthesis in plants. However, the TPS gene family and its expression patterns in different growth stages of Dendrobium nobile remain unexplored. This study aims to systematically identify and analyze TPS family members using whole genome sequencing. Results revealed the identification of
Lei Li   +9 more
wiley   +1 more source

Transcriptomic and Proteomic Analyses Reveal the Anti–Ovarian Cancer Activity of Lotus Seedpod Polysaccharide on SKOV3 Cells via RIPK1/RIPK3/MLKL Pathway

open access: yesJournal of Food Biochemistry, Volume 2025, Issue 1, 2025.
This study aimed to investigate the anti–ovarian cancer activity of lotus seedpod polysaccharide (LSP) on human ovarian cancer SKOV3 cells and the relevant molecular mechanisms. The toxicity of LSP was also assessed in normal mice. The results showed that LSP inhibited SKOV3 proliferation and induced cell apoptosis.
Jin-Shi Chen   +9 more
wiley   +1 more source

The Circadian Rhythm of Asthma Immune Metabolism

open access: yesJournal of Immunology Research, Volume 2025, Issue 1, 2025.
Asthma is a chronic inflammatory respiratory disease with a distinct circadian rhythm. Common symptoms like cough, wheezing, and dyspnea, are worse at night and in the early morning (around 4 a.m.). The circadian pattern of asthma is intrinsically connected to the body’s internal clock, which regulates a wide range of biological processes via ...
Manchen Lu   +11 more
wiley   +1 more source

Plant‐Origin Compounds and Materials for Advancing Bone Tissue Engineering and 3D Bioprinting: Traditional Medicine Aspects and Current Perspectives

open access: yesJournal of Tissue Engineering and Regenerative Medicine, Volume 2025, Issue 1, 2025.
Bone defects are becoming a true challenge in global health care due to the aging population and higher prevalence of musculoskeletal disorders. The interest in using plant‐origin compounds and plant‐derived biomaterials in bone tissue engineering (BTE) has been increased due to their availability (abundance), safety, biocompatibility, biodegradability,
Jyrki Heinämäki   +7 more
wiley   +1 more source

Mechanism of action of “cistanche deserticola–Polygala” in treating Alzheimer's disease based on network pharmacology methods and molecular docking analysis

open access: yesIET Systems Biology, Volume 18, Issue 6, Page 271-284, December 2024.
Differential expression of genes between AD patients and the normal population (a) Basic information of GSE5281 dataset. AD patient samples were labelled with green, while control group samples were labelled with purple. (b) Uniform manifold approximation and projection(UMAP) of differentially expressed gene (DEG) in GSE5281. (c) Expression density map
Shaoqiang Wang, Yifan Wang
wiley   +1 more source

Memory-Enhancing Effects of the Crude Extract of Polygala tenuifolia on Aged Mice.

open access: yes, 2017
Learning and memory disorders arise from distinct age-associated processes, and aging animals are often used as a model of memory impairment. The root of Polygala tenuifolia has been commonly used in some Asian countries as memory enhancer and its memory

core   +1 more source

Quasi-targeted metabolomics analysis reveals linkage between chemical composition and different post-harvest processing methods of Polygala tenuifolia

open access: yesMedicinal Plant Biology
The dried root bark of Polygala tenuifolia is widely recognized in traditional Chinese medicine (TCM) for its role in promoting cerebral tranquility.
Shuai Liu   +9 more
doaj   +1 more source

Oral Chinese herbal medicine combined with donepezil for mild cognitive impairment: A systematic review and meta‐analysis

open access: yesJournal of the American Geriatrics Society, Volume 72, Issue 12, Page 3890-3902, December 2024.
Abstract Background This study aims to evaluate the add‐on effects of oral Chinese herbal medicine (CHM) for mild cognitive impairment (MCI), when used in addition to donepezil compared to donepezil alone. Methods Randomized controlled trials comparing these treatments across all types of MCI were identified from nine databases and three registers ...
Lingling Liu   +4 more
wiley   +1 more source

The primers used for RT-qPCR experiment in Polygala tenuifolia Willd.

open access: yes
The primers used for RT-qPCR experiment in Polygala tenuifolia Willd.
Xian Gu (5858801)   +8 more
core   +1 more source

The Protective Effects of PSM-04 Against Beta Amyloid-Induced Neurotoxicity in Primary Cortical Neurons and an Animal Model of Alzheimer’s Disease

open access: yesFrontiers in Pharmacology, 2019
Polygala tenuifolia Willdenow is a herb known for its therapeutic effects in insomnia, depression, disorientation, and memory impairment. In Alzheimer’s disease (AD) animal model, there has been no report on the effects of memory and cognitive impairment.
Hyunjun Park   +9 more
doaj   +1 more source

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