Results 81 to 90 of about 1,186 (173)

Four New Phenolic Glycosides from Polygala tenuifolia.

Chemical and Pharmaceutical Bulletin, 1991
Four new phenolic glycosides, tenuifolisides A (1), B (2), C (3), and D (4) together with a known phenolic glyciside, β-D-(3-O-sinapoyl)-fructofuranosyl-α-D-(6-O-sinapoyl)-glucopyranoside (5) were isolated from the roots of Polygala tenuifolia.
IKEYA, Yukinobu, SUGAMA, Ko, OKADA, Minoru, MITSUHASHI, Hiroshi   +3 more
openaire   +2 more sources

Популяционная стратегия Polygala tenuifolia Willd

Вестник Томского государственного университета. Биология, 2012
An aggregate of species features within the area characterizes ecological and phytocoenotic potencies and their manifestation in different situations determines populational strategy. The aim is to study individual characters and establish a type of Polygala tenuifolia populational strategy. P. tenuifolia, this is a perennial polycarpic taproot, caudex-
openaire   +3 more sources

Excavating Precursors from the Traditional Chinese Pair Herbs Polygala tenuifolia and Gastrodia elata: Synthesis, Anticonvulsant Activity Evaluation of 3,4,5-Trimethoxycinnamic Acid (TMCA) Peptide Analogs

Pharmaceuticals
Background: Epilepsy comprises a range of disorders affecting the central nervous system (CNS) characterized by recurrent seizures, impacting approximately 60 million individuals globally.
Zefeng Zhao, Mengchen Lei, Yujun Bai, Haifa Qiao   +3 more
doaj   +1 more source

Genetic diversity and population structure of a protected species: Polygala tenuifolia Willd

Comptes Rendus. Biologies, 2018
Polygala tenuifolia Willd. is an important protected species used in traditional Chinese medicine. In the present study, amplified fragment length polymorphism (AFLP) markers were employed to characterize the genetic diversity in wild and cultivated P.
Yan Qun, Peng, Ling Ling, Fan, Fu Ying, Mao, Yun Sheng, Zhao, Rui, Xu, Yu Jie, Yin, Xin, Chen, De Guang, Wan, Xin Hui, Zhang   +8 more
openaire   +2 more sources

Neuroprotective effects of tenuigenin on neurobehavior, oxidative stress, and tau hyperphosphorylation induced by intracerebroventricular streptozotocin in rats

Brain Circulation, 2018
BACKGROUND: Tenuigenin (TEN), a major active component of the Chinese herb Polygala tenuifolia root, has been used to improve memory and cognitive function in Traditional Chinese Medicine for centuries.
Xiao-Bo Huang, Yu-Jing Chen, Wen-Qiang Chen, Ning-Qun Wang, Xi-Ling Wu, Yan Liu   +5 more
doaj   +1 more source

Combination of tenuigenin-based Polygala tenuifolia willd. root extract and forsythoside a improved Alzheimer’s disease

Tenuigenin is a kind of the main active ingredients in roots of Polygala tenuifolia Willd. (a species in the genus Polygala, family Polygalaceae) and forsythoside A (FA) is one of the main active ingredients of Forsythia suspensa (Thunb.) Vahl.
Guocui Liang (18255538), Liwei Zhang (490121), Chengxia Gao (18255541), Huizhi Du (1761670)   +3 more
core   +1 more source

Inhibitory constituents from the aerial parts of Polygala tenuifolia on LPS-induced NO production in BV2 microglia cells

, 2013
Five new phenolic glycosides, tenuisides A-E (1-5), and a new megastigmane glycoside, tenuiside F (6), along with seventeen known compounds (7-23) were isolated from the aerial parts of Polygala tenuifolia Willd.
Jiang, Yong, Zeng, Ke-Wu, Tu, Peng-Fei, Wang, Shu, Shi, Tian-Xing   +4 more
core   +1 more source

Synergistic neuroprotective effects of two herbal ingredients via CREB-dependent pathway

Frontiers in Pharmacology, 2016
As two natural oligosaccharide esters, 3,6’-Disinapoyl sucrose (DISS) and tenuifolisideA (TFSA) are originating from the root of Polygala tenuifolia Willd, a traditional Chinese medicine used in treatment of mental disorders.
Xu Liu, Dongxiao Wang, Runqing Zhao, Xianzhe Dong, Ping Liu, Yuan Hu   +5 more
doaj   +1 more source

Tenuigenin protects dopaminergic neurons from inflammation via suppressing NLRP3 inflammasome activation in microglia

Journal of Neuroinflammation, 2017
Background Emerging evidence indicates that nod-like receptor family, pyrin domain-containing 3 (NLRP3) inflammasome-induced inflammation plays a crucial role in the pathogenesis of Parkinson’s disease (PD).
Zheng Fan, Zhigang Liang, Hui Yang, Yuting Pan, Yan Zheng, Xiaomin Wang   +5 more
doaj   +1 more source

Comprehensive evaluation of chemical constituents and antioxidant activity between crude and processed Polygalae radix based on UPLC-Q-TOF-MS/MS combined with multivariate statistical analysis

Heliyon
Polygalae radix (PR) is a famous herbal medicine obtained by drying the root of Polygala tenuifolia Willd., one of the traditional Chinese medicines (TCM) that can be used for healthy food. There are three main processed methods of PR, including removing
Yao Luo, Benxiang Hu, Haiyue Ji, Yiyao Jing, Xiaoling Dang, Han Zhang, Bo Li, Gang Zhang, Yongang Yan, Bingyue Yang, Liang Peng   +10 more
doaj   +1 more source