Results 71 to 80 of about 29,329 (143)

Otoprotective Effect of 2,3,4′,5-Tetrahydroxystilbene-2-O-β-d-Glucoside on Gentamicin-Induced Apoptosis in Mouse Cochlear UB/OC-2 Cells

Molecules, 2020
Excessive levels of reactive oxygen species (ROS) lead to mitochondrial damage and apoptotic cell death in gentamicin-induced ototoxicity. 2,3,4’,5-Tetrahydroxystilbene-2-O-β-d-glucoside (THSG), a bioactive constituent, isolated from Polygonum ...
Yu-Hsuan Wen, Jia-Ni Lin, Rong-Shuan Wu, Szu-Hui Yu, Chuan-Jen Hsu, Guo-Fang Tseng, Hung-Pin Wu   +6 more
doaj   +1 more source

Immunization against Medically Important Human Coronaviruses of Public Health Concern

Canadian Journal of Infectious Diseases and Medical Microbiology, Volume 2024, Issue 1, 2024.
SARS‐CoV‐2 is a virus that affects the human immune system. It was observed to be on the rise since the beginning of 2020 and turned into a life‐threatening pandemic. Scientists have tried to develop a possible preventive and therapeutic drug against severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) and other related coronaviruses by ...
Nabil A. Nimer, Seema N. Nimer, Benjamin Liu   +2 more
wiley   +1 more source

In vitro free radicals scavenging activities of polysaccharide from Polygonum Multiflorum Thunb

, 2011
The crude polysaccharide (PMTP) was isolated from Polygonum Multiflorum Thunb through hot water extraction followed by ethanol precipitation. Through antioxidant assay in vitro, the results exhibited PMTP has powerful scavenging abilities, especially on ...
Fan, YJ (reprint author), Sichuan Agr Univ, Chengdu Campus, Chengdu 611130, Peoples R China., Fan, Yijun, Luo, Aoshuang, Luo, Aoxue   +3 more
core  

Farnesyl protein transferase inhibitory components of Polygonum multiflorum

, 2009
The methanolic extract of the roots of Polygonum multiflorum (Polygonaceae) was found to show inhibitory activity towards farnesyl protein transferase (FPTase).
J H Lee, H W Park, J S Park, E J Kim, J H Yang, N I Baek, Byoung-Mog Kwon, S H Kim, S I Lee, D K Kim, B S Chae   +10 more
core   +1 more source

Tissue-Specific Analysis of Secondary Metabolites Creates a Reliable Morphological Criterion for Quality Grading of Polygoni Multiflori Radix

Molecules, 2018
In commercial herbal markets, Polygoni Multiflori Radix (PMR, the tuberous roots of Polygonum multiflorum Thunb.), a commonly-used Chinese medicinal material, is divided into different grades based on morphological features of size and weight. While more
Li Liang, Jun Xu, Zhi-Tao Liang, Xiao-Ping Dong, Hu-Biao Chen, Zhong-Zhen Zhao   +5 more
doaj   +1 more source

Integrating Targeted and Untargeted Metabolomics to Investigate the Processing Chemistry of Polygoni Multiflori Radix

Frontiers in Pharmacology, 2018
Polygoni Multiflori Radix (PMR, Heshouwu in Chinese), derived from the tuberous roots of Polygonum multiflorum Thunb., is a widely-used Chinese medicinal material.
Li Liang, Jun Xu, Wen-Wen Zhou, Eric Brand, Hu-Biao Chen, Zhong-Zhen Zhao   +5 more
doaj   +1 more source

Investigation on the Therapeutic Effect of Polygonum multiflorum Thunb. in Chronic Stress-Induced Hair Loss in Mice Coupled with Metabolomics and Proteomics

World Journal of Traditional Chinese Medicine
Objective: Stress is the main factor that leads to hair loss, and no effective therapeutics have been developed for stress alopecia. Polygonum multiflorum Thunb.
Yong-Kang Zhao, Rui-Xian Guo, Rui-Sheng Li, Wei Shi, Hai-Ying Gong, Run-Ran Ma, Han Gao, Zhen Li, Ke-Jian Hu, Zhao-Fang Bai, Xiao-He Xiao, Qing-Ce Zang, Wei-Jun Kong, Peng Li, Ming Niu, Jia-Bo Wang, Yuan Gao   +16 more
doaj   +1 more source

A Comprehensive and System Review for the Pharmacological Mechanism of Action of Rhein, an Active Anthraquinone Ingredient

Frontiers in Pharmacology, 2016
Rhein is a major medicinal ingredient isolated from several traditional Chinese medicines, including Rheum palmatum L., Aloe barbadensis Miller, Cassia angustifolia Vahl., and Polygonum multiflorum Thunb.
Hao Sun, Guangwen Luo, Dahui Chen, Zheng Xiang   +3 more
doaj   +1 more source

Micropropagation of Polygonum multiflorum THUNB and quantitative analysis of the anthraquinones emodin and physcion formed in in vitro propagated shoots and plants

, 2014
An efficient and rapid protocol for in vitro induction and complete plant regeneration of Polygonum multiflorum THUNB has been developed. Nodal explants were grown in vitro on Murashige and Skoog's (MS) basal medium containing different concentrations of
Nalawade, S.M., Tsay, H.S., Mulabagal, V., Yeh, M.S., Lin, L.C.   +4 more
core   +1 more source

Antioxidant Activities of Maillard Reaction Products Produced in the Steaming Process of Root

Natural Product Communications, 2011
The root of Polygonum multiflorum Thunb. (Heshouwu in Chinese) is one of the most popular herbs used in traditional Chinese medicine (TCM). However, after steam processing (Zhi-heshouwu in Chinese), the root is known to have different properties and ...
Zhenli Liu, Yuanyan Liu, Zhimao Chao, Zhiqian Song, Chun Wang, Aiping Lu   +5 more
doaj   +1 more source