Results 201 to 210 of about 55,739 (236)
Comparative gene expression analysis in closely related dermatophytes reveals secondary metabolism as a candidate driver of virulence. [PDF]
Microbiol SpectrMachová L +5 more
europepmc +1 more source
Empowering molecular complexity <i>via</i> biocatalysis: emerging blueprints in the total synthesis of medicinally relevant natural products. [PDF]
RSC Med ChemYadav RN +6 more
europepmc +1 more source
Cochlioquinones 1968-2024: Chemistry, Biosynthesis, and Biological Activities with Future Perspectives. [PDF]
J Fungi (Basel)Fang H, Li Q, Chen L, Ding G.
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Comprehensive genomic and metabolomic profiling of <i>Weissella confusa</i> UTNCys2-2 highlights bioactive potential. [PDF]
Front MicrobiolTenea GN.
europepmc +1 more source
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2016
Polyketides are a fascinating class of natural products with highly diverse, often complex structures combined with a likewise impressive breath of strong and selective biological activities. This chapter discusses the logic of biosynthetic polyketide assembly.
Schaefers, Françoise +7 more
openaire +3 more sources
Polyketides are a fascinating class of natural products with highly diverse, often complex structures combined with a likewise impressive breath of strong and selective biological activities. This chapter discusses the logic of biosynthetic polyketide assembly.
Schaefers, Françoise +7 more
openaire +3 more sources
Towards engineered polyketides
Expert Opinion on Investigational Drugs, 1998Rapid advances have been made over the past 10 years in the identification of the biosynthetic machinery that carries out the biosynthesis of polyketide natural products. Many such compounds are used in various therapeutic areas, including antibacterials, anticancer, antifungals and cholesterol lowering.
J, Staunton, B, Wilkinson
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Biosynthesis of polyketides by trans-AT polyketide synthases
Natural Product Reports, 2016This review discusses the biosynthesis of natural products that are generated bytrans-AT polyketide synthases, a family of catalytically versatile enzymes that represents one of the major group of proteins involved in the production of bioactive polyketides.
Helfrich Eric J N, Piel Jörn
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Engineering of modular polyketide synthases to produce novel polyketides
Current Opinion in Biotechnology, 1998Polyketides are important natural products produced by Actinomycetes and other organisms via the polymerization of coenzyme A-activated carboxylic acids. Modular polyketide synthases are large multifunctional enzymes that direct the biosynthetic process using a dedicated 'module' for each polymerization reaction, which specifies the unit to be ...
, Carreras, , Santi
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