Polyketide - Open Access .click

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1994
This chapter discusses the condensation of acetyl-SCoA with malonyl-SCoA units that gives rise to numerous aromatic compounds, many of which have meta-disposition of hydroxyl groups. It mentions products of the polyketide pathway and its typical examples, such as 6-methylsalicyclicacid, antifungal compound griseofulvin, mycotoxins patulin, and ...
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Cell-free synthesis of polyketides by recombinant erythromycin polyketide synthases

Nature, 1995
Modular polyketide synthases (PKSs) are complex multi-enzyme proteins that catalyse the bacterial biosynthesis of many pharmaceutically useful polyketides. The PKSs are organized into a series of modules, each containing the active catalytic sites required for one step in the synthesis process.
R, Pieper, G, Luo, D E, Cane, C, Khosla
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Production of a novel polyketide through the construction of a hybrid polyketide synthase

Gene, 1996
The lactone rings of the polyketides platenolide and tylactone are synthesized by condensation of acetate-, proprionate-, and butyrate-derived precursors. A hybrid tylactone/platenolide synthase was constructed to determine if the choice of substrate is programmed by the polyketide synthase and to ascertain if a substrate different than that normally ...
S, Kuhstoss +4 more
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ChemInform Abstract: Biosynthesis of Polyketides by trans‐AT Polyketide Synthases

ChemInform, 2010
AbstractReview: 436 refs.
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Polyketides

2023
Borhane Eddine Cherif Ziani +3 more
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Polyketides

1981
Margaret L. Vickery, Brian Vickery
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The biosynthesis of polyketides

Natural Product Reports, 1984
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Polyketides

2009
C.P. Ridley, C. Khosla
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Catalytic Control of Spiroketal Formation in Rubromycin Polyketide Biosynthesis

Angewandte Chemie - International Edition, 2021
Marina Toplak +2 more
exaly