Results 31 to 40 of about 12,305,089 (195)
Antibiotics, 2023 Fosfomycin disodium is a potential therapeutic option to manage difficult-to-treat infections, especially when combined with other antimicrobials. In this study, we evaluated the activity of fosfomycin in combination with meropenem or polymyxin B against
Aghata Cardoso da Silva Ribeiro +7 more
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, 2023 Wenjuan Yan,1,* Jiaojiao Wu,2,* Shanmei Wang,1 Qi Zhang,1 Youhua Yuan,1 Nan Jing,1 Jiangfeng Zhang,1 Hangchan He,3 Yi Li1 1Department of Clinical Microbiology, Henan Provincial People’s Hospital, People’s Hospital of Zhengzhou University, People ...
Wu J +8 more
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Brazilian Journal of Infectious Diseases, 2018 A retrospective cohort study, were evaluated: polymyxin B plus aminoglycosides or polymyxin B plus other antibiotics. Any degree of acute kidney injury occurred in 26 (86.6%) patients.
Cely Saad Abboud +4 more
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Personalizing Polymyxin B dosing using an adaptive feedback control algorithm [PDF]
, 2018 Polymyxin B is used as an antibiotic of last resort for patients with multidrug-resistant Gram-negative bacterial infections; however, it carries a significant risk of nephrotoxicity.
Keith S. Kaye +13 more
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Inactivation of Endotoxin by Polymyxin B [PDF]
Antimicrobial Agents and Chemotherapy, 1974 The limulus gelation assay was utilized to investigate endotoxin inactivation by a number of antibiotics in vitro. Endotoxin activity was sharply reduced by polymyxin B and sodium colistimethate. The effect of the polymyxin was not significantly inhibited by 0.001 M calcium or 90% serum.
openaire +2 more sources
Polymyxin B-related neurotoxicity: a brief case report
, 2023 Polymyxin B and colistin are considered the last therapeutic option to treat infections caused by highly drug-resistant bacteria. However, their administration may lead to various adverse effects such as nephrotoxicity, neurotoxicity, and allergic ...
HALAÇLI, BURÇİN +3 more
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Lipid Microenvironment Modulates the Pore-Forming Ability of Polymyxin B
, 2022 The ability of polymyxin B, an antibiotic used to treat infections caused by multidrug-resistant Gram-negative bacteria as a last-line therapeutic option, to form ion pores in model membranes composed of various phospholipids and lipopolysaccharides was ...
Efimova, Svetlana S. +5 more
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Risk factors for polymyxin B-associated acute kidney injury
International Journal of Infectious Diseases, 2022 Objectives: This study aimed to assess the current incidence and risk factors for polymyxin B-associated acute kidney injury (AKI) in Chinese hospitals for a more effective clinical use for polymyxin B.
Kang Chang +16 more
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Microbiology Spectrum, 2022 Polymyxin B is a last-line antibiotic for extensively resistant Gram-negative bacterial infection. Skin hyperpigmentation is a serious side effect induced by polymyxin B that severely compromises the psychological health and compliance of patients.
Chuhan Zhang +8 more
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The Actions of Polymyxin B and Histamine on Ganglionic Transmission
, 1972 The ganglionic effects of histamine and the histamine-liberating agent polymyxin B were studied in the cat. Nictitating membrane contractions and postganglionic action potentials were used to monitor the actions of these drugs on the superior cervical ...
S. B. Gertner, H. E. Brezenoff
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