Results 51 to 60 of about 1,357 (186)
Analysis of drug efficacy for inflammatory skin on an organ-chip system
Bacterial skin infections cause a variety of common skin diseases that require drugs that are safer than antibiotics and have fewer side effects.
Qianghua Quan +7 more
doaj +1 more source
Introduction: Traditional Chinese medicine compound preparations have become an increasingly utilized strategy for tumour treatment. Qidongning Formula (QDN) is a kind of antitumour compound preparation used in hospitals, and it can inhibit the growth of
Di Zhou +4 more
doaj +1 more source
Additional file 2: This PDF contains all the additional figures (Figure S1-S6) associated with the manuscript. Figure numbers and titles are listed as follows: Figure S1. BUSCO assessment results. Figure S2.
Jiawei Guo (1488853) +7 more
core +1 more source
ABSTRACT Alcoholic liver disease (ALD) is a multifaceted disorder in which oxidative injury, iron‐dependent ferroptosis, steatosis, and inflammation are closely intertwined. Consequently, therapeutic strategies targeting a single pathway often produce limited clinical benefits.
Hongyan Feng +7 more
wiley +1 more source
Traditional Chinese Medicine for lung cancer: Mechanisms, clinical evidence, and future perspectives
Graphical abstract represents the risk factors for lung cancer, TCM efficacy and clinical outcomes to future challenges. Abstract Lung cancer remains a leading cause of global cancer mortality. Despite advances in conventional treatments such as surgery, chemotherapy, targeted therapy, and immunotherapy, challenges including drug resistance, toxicity ...
Zhangdeng Chen, Liujun Bao
wiley +1 more source
Fluorophore-Appended Steroidal Saponin (Dioscin and Polyphyllin D) Derivatives
The synthesis of three fluorophore-appended derivatives of dioscin and polyphyllin D is reported herein. Starting from trillin, dansyl derivatives A−C were prepared in overall yields of 7−12% over 7−10 steps.
Zhiqi Yang (2692909) +4 more
core +1 more source
SUMMARY Whole‐genome duplication (WGD, or polyploidization) is a major evolutionary force in plants, yet the genomic, transcriptional, and metabolic consequences of autopolyploidy remain less understood than those of allopolyploidy. Dioscorea nipponica, a medicinal species producing diosgenin‐type steroidal saponins, harbors both diploid and ...
Shan‐Shan Li +8 more
wiley +1 more source
ABSTRACT Structural characterization of complex carbohydrates remains challenging. This study employed methylation, acid hydrolysis, 1‐phenyl‐3‐methyl‐5‐pyrazolone (PMP) derivatization, and ultra‐high performance liquid chromatography–tandem mass spectrometry (UHPLC–MS/MS) to determine monosaccharides, glycosidic linkages, and sequence of ...
Hui Yan +4 more
wiley +1 more source
The role of Rhizoma Paridis saponins on anti-cancer: The potential mechanism and molecular targets
Cancer is a disease characterized by uncontrolled cell proliferation, leading to excessive growth and invasion that can spread to other parts of the body.
Famin Ke +7 more
doaj +1 more source
Cuproptosis Inducers in Cancer Therapy: State of the Art and Challenges
Cuproptosis is emerging as a distinct copper‐dependent cell death pathway, highlighting copper as a potential metabolic vulnerability in cancer. This review examines how coordination chemistry, redox regulation, and nanomaterial design shape Cu reactivity and therapeutic outcomes.
Chiara Ragusa, Valentina Oliveri
wiley +1 more source

