Results 41 to 50 of about 1,357 (186)

Data_Sheet_1_Endophyte-inoculated rhizomes of Paris polyphylla improve polyphyllin biosynthesis and yield: a transcriptomic analysis of the underlying mechanism.CSV

, 2023
IntroductionPolyphyllin from Paris polyphylla var. yunnanensis exhibits anti-inflammatory, analgesic, antibacterial, and antiviral properties. However, the current production of polyphyllin can barely meet market demand.
Lufeng Liu (16011029), Ying Yang (24175), Qing Zhang (1802), Tao Liu (10785), Yumei Dong (819762), Congfang Xi (17303854), Sheng Chang (649642), Yu Liu (6938), Yunchao He (17303857), Bo Cai (62436)   +9 more
core   +1 more source

Polyphyllin VII attenuated RANKL-induced osteoclast differentiation via inhibiting of TRAF6/c-Src/PI3K pathway and ROS production

BMC Musculoskeletal Disorders, 2020
Background Osteoporosis is a worldwide severe bone disease. This study aimed to evaluate the effect of polyphyllin VII on the genesis of osteoclasts from bone marrow macrophages (BMMs) and its potentiality as a therapeutic drug for osteoporosis.
Long Zhou, Hanyi Song, Yiqi Zhang, Zhaozhou Ren, Minghe Li, Qin Fu   +5 more
doaj   +1 more source

Polyphyllin VII induces apoptosis in HepG2 cells through ROS-mediated mitochondrial dysfunction and MAPK pathways [PDF]

, 2016
Polyphyllin VI (PP6) inhibited the proliferation of human cancer cells (HepG2, A549, MCF7, SKOV3, Hep3B, Bel7402 and 7721). Cells were treated with increasing concentrations of PP6 for 24 h and cell viability was determined by MTT assay as described in ...
Shenghui Chen, Jiaolin Bao, Yitao Wang, Xuejing Jia (847990), Peng Li, Yitao Wang (313075), Chengwei He (125487), Peng Li (69518), Xuejing Jia, Huanxing Su (104291), Zhinan Mei (847991), Yulin Zhang (510822), Chao Zhang, Huanxing Su, Jiaolin Bao (519829), Chengwei He, Shenghui Chen (801841), Zhinan Mei, Yulin Zhang, Jian-Bo Wan, Jian-Bo Wan (500188), Kai Wang, Chao Zhang (51048), Kai Wang (21246)   +23 more
core   +1 more source

Data_Sheet_2_Endophyte-inoculated rhizomes of Paris polyphylla improve polyphyllin biosynthesis and yield: a transcriptomic analysis of the underlying mechanism.CSV

, 2023
IntroductionPolyphyllin from Paris polyphylla var. yunnanensis exhibits anti-inflammatory, analgesic, antibacterial, and antiviral properties. However, the current production of polyphyllin can barely meet market demand.
Lufeng Liu (16011029), Ying Yang (24175), Qing Zhang (1802), Tao Liu (10785), Yumei Dong (819762), Congfang Xi (17303854), Sheng Chang (649642), Yu Liu (6938), Yunchao He (17303857), Bo Cai (62436)   +9 more
core   +1 more source

Polyphyllin I Inhibits Propionibacterium acnes-Induced Inflammation In Vitro [PDF]

Inflammation, 2018
Propionibacterium acnes (P. acnes) has been implicated in the progression of acne inflammation. Because current acne medications have various side effects, it is necessary to explore alternative medications possessing anti-inflammatory activity against P. acnes. We investigated the inhibitory effects of polyphyllin I (PPI) on P.
Zhu, Tingting, Wu, Wenjuan, Yang, Shuyun, Li, Donglin, Sun, Dongjie, He, Li   +5 more
openaire   +2 more sources

Polyphyllin I Effects Candida albicans via Inhibition of Virulence Factors

Evidence-Based Complementary and Alternative Medicine, 2023
Paris polyphylla is often used in Chinese medicine to treat conditions such as carbuncles, trauma, snake bites, and mosquito bites. In the present study, we investigated the effect and mechanism of the morphological transition and extracellular phospholipase activity of Candida albicans treated with polyphyllin I (PPI).
Ai-Mei Sun, Ying-Xian Wang, Guo-Xian Hu, Li Li, Rui-Rui Wang   +4 more
openaire   +2 more sources

Presentation_1_Endophyte-inoculated rhizomes of Paris polyphylla improve polyphyllin biosynthesis and yield: a transcriptomic analysis of the underlying mechanism.pdf

, 2023
IntroductionPolyphyllin from Paris polyphylla var. yunnanensis exhibits anti-inflammatory, analgesic, antibacterial, and antiviral properties. However, the current production of polyphyllin can barely meet market demand.
Lufeng Liu (16011029), Ying Yang (24175), Qing Zhang (1802), Tao Liu (10785), Yumei Dong (819762), Congfang Xi (17303854), Sheng Chang (649642), Yu Liu (6938), Yunchao He (17303857), Bo Cai (62436)   +9 more
core   +1 more source

Additional file 3 of Dihydromyricetin inhibits African swine fever virus replication by downregulating toll-like receptor 4-dependent pyroptosis in vitro

, 2023
Additional file 3. Cytotoxicity of resatorvid, EUK-134, disulfiram, polyphyllin,and RS 09 TFA toward PAMs. The effects of resatorvid, EUK-134, disulfiram, polyphyllin, and RS 09 TFA on the cellular viability of PAMs were examined using the cell-counting ...
Zebu Song (16536887), Guihong Zhang (16536890), Lang Gong (5704655), Zezhong Zheng (8062679), Hao Chang (801491), Yang Chen (9737), Zhi Wei (258408), Yanchen Guo (5273846), Yankuo Sun (4898941)   +8 more
core   +1 more source

The protective effect of polyphyllin I on myocardial ischemia/ reperfusion injury in rats

Annals of Translational Medicine, 2020
Myocardial ischemia/reperfusion (I/R) injury has become a global public health concern. An increasing amount of evidence has shown that polyphyllin I (PPI) has anti-apoptotic and antioxidant functions. This study was performed to evaluate the cardioprotective effects of PPI in a rat model of myocardial I/R injury and the underlying mechanism.We exposed
Huang, Ruizhen, Shu, Jia, Dai, Xiaoqin, Liu, Yanru, Yu, Fang, Shi, Gang   +5 more
openaire   +2 more sources

Chemical structures of polyphyllin I, II, VI and VII.

, 2014
Chemical structures of polyphyllin I, II, VI and VII.
Tianjun Yuan (524010), Ying Hou (492289), Wei Li (7081), Hang Jin (524013), Yuanzhong Wang (524012), Yanli Zhao (462683), Tao Shen (209797), Shihua Yang (524011), Ji Zhang (70438)   +8 more
core   +1 more source