Results 81 to 90 of about 1,357 (186)
Journal of Analytical Methods in Chemistry, 2016 A fast method was developed by ultra high performance liquid chromatography (UHPLC) for simultaneous determination of polyphyllin I and polyphyllin II.
Yuangui Yang +4 more
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Oncotarget, 2015 Biotransformation by the endophytes of certain plants changes various compounds, and this 'green' chemistry becomes increasingly important for finding new products with pharmacological activity. In this study, polyphyllin VII (PPL7) was biotransformed by endophytes from the medicinal plant Paris polyphylla Smith, var. yunnanensis.
He, Dong-Xu +8 more
openaire +2 more sources
Polyphyllin I Ameliorates Collagen-Induced Arthritis by Suppressing the Inflammation Response in Macrophages Through the NF-κB Pathway [PDF]
, 2018 Background: Rheumatoid arthritis (RA) is a chronic autoimmune disorder, characterized by an increased number of M1-like macrophages in the joints. Polyphyllin I (PPI), one of the main components in the Rhizoma of Paris polyphyllin, displays a selective ...
Qianqian Liang +8 more
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Saponins from Chinese Medicines as Anticancer Agents
Molecules, 2016 Saponins are glycosides with triterpenoid or spirostane aglycones that demonstrate various pharmacological effects against mammalian diseases. To promote the research and development of anticancer agents from saponins, this review focuses on the ...
Xiao-Huang Xu +7 more
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The biosynthesis of trillin 6'-<i>O</i>-glucoside: A low-abundance yet pharmacologically active polyphyllin from <i>Paris polyphylla</i>. [PDF]
Synth Syst BiotechnolNatural products from medicinal plants serve as an invaluable resource for drug discovery and development. However, low-abundance natural products are often understudied due to the challenges of obtaining sufficient quantities for pharmacological testing
Suo Y +9 more
europepmc +2 more sources
, 2022 Polyphyllin II (PPII) is a natural steroidal saponin occurring in Rhizoma Paridis. It has been demonstrated to exhibit anti-cancer activity against a variety of cancer cells.
Li, Jun-Kui +21 more
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Effects of polyphyllin D on the induction of apoptosis in human hepatocellular carcinoma HepG2 cells and its multidrug resistant derivative RHepG2 cells. [PDF]
, 2004 Ong Chik Ying Rose.Thesis (M.Phil.)--Chinese University of Hong Kong, 2004.Includes bibliographical references (leaves 181-195).Abstracts in English and Chinese.Acknoledgements --- p.iList of Abbreviations --- p.iiAbstract --- p.iiiAbstract in Chinese
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Pharmacology Research & PerspectivesCytochrome P450 enzymes (CYPs) play a crucial role in phase I metabolic reactions. The activity of CYPs would affect therapeutic efficacy and may even induce toxicity.
Erhao Wang, Mengxi Wang, Ming Gao
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BMC GenomicsBackground The excavation and utilization of endophytic fungi from medicinal plants is highly important for the development of new drugs. The endophytic fungus Aspergillus tamarii TPD11, which was isolated and obtained by the authors in the previous ...
Qing Zhang +11 more
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Synergistic anticancer effects of polyphyllin I and evodiamine on freshly-removed human gastric tumors. [PDF]
, 2013 The present study was designed to examine the anticancer effect of Traditional Chinese Medicine of polyphyllin I (PPI) and evodiamine (EVO) on freshly-removed gastric tumor tissues.Sixty freshly-removed gastric tumor tissues were collected.
Wenxian Guan (419493) +26 more
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