Results 51 to 60 of about 22,479,757 (178)

Network Pharmacology Reveals Polyphyllin II as One Hit of Nano Chinese Medicine Monomers against Nasopharyngeal Carcinoma

open access: yes, 2021
Nasopharyngeal carcinoma (NPC) is a malignant tumor in southern China, and nano Traditional Chinese Medicine (TCM) represents great potential to cancer therapy.
Xian-Yu Bai   +8 more
core   +1 more source

Polyphyllin VII induces apoptosis in HepG2 cells through ROS-mediated mitochondrial dysfunction and MAPK pathways [PDF]

open access: yes, 2016
Polyphyllin VI (PP6) inhibited the proliferation of human cancer cells (HepG2, A549, MCF7, SKOV3, Hep3B, Bel7402 and 7721). Cells were treated with increasing concentrations of PP6 for 24 h and cell viability was determined by MTT assay as described in ...
Shenghui Chen   +23 more
core   +1 more source

Chemical structures of polyphyllin I, II, VI and VII.

open access: yes, 2014
Chemical structures of polyphyllin I, II, VI and VII.
Tianjun Yuan (524010)   +8 more
core   +1 more source

Bioactive secondary metabolites in Paris polyphylla Sm. and their biological activities: A review

open access: yesHeliyon, 2022
Paris polyphylla Sm. is an important medicinal plant used to treat a variety of diseases through traditional medicine systems such as Ayurveda, Tibetan traditional medicines, Chinese traditional medicines, and others around the world.
Chandra Bahadur Thapa   +6 more
doaj   +1 more source

Effects of polyphyllin I on growth inhibition of human non-small lung cancer cells and in xenograft [PDF]

open access: yesActa Biochimica et Biophysica Sinica, 2010
Polyphyllin I (PPI), a small molecular monomer extracted from Rhizoma of Paris polyphyllin, shows strong anticancer effects in previous study. Human lung adenocarcinoma A549 cells, human lung squamous cell carcinoma SK-MES-1 cells, and human lung large cell carcinoma H460 cells were cultured and then treated with PPI.
Minjian, Kong   +4 more
openaire   +2 more sources

The average contents of polyphyllin I, II, VII and total steroid saponins in Paris from different geographical regions: (1) Central Yunnan; (2) Northwestern Yunnan; (3) Southwestern Yunnan; (4) Southeastern Yunnan; (5) Guizhou; (6) Guangxi.

open access: yes, 2014
The average contents of polyphyllin I, II, VII and total steroid saponins in Paris from different geographical regions: (1) Central Yunnan; (2) Northwestern Yunnan; (3) Southwestern Yunnan; (4) Southeastern Yunnan; (5) Guizhou; (6) Guangxi.
Tianjun Yuan (524010)   +8 more
core   +1 more source

Polyphyllin VII increases sensitivity to gefitinib by modulating the elevation of P21 in acquired gefitinib resistant non-small cell lung cancer

open access: yes, 2017
Blockade of EGFR with reversible EGFR tyrosine kinase inhibitors (TKIs) is considered the frontline strategy for advanced NSCLC with EGFR mutations. However, acquired resistance to EGFR-TKI has been observed, resulting in disease progression and limited ...
Zhenghua Fei, Hao Jiang, Honggang Wang
core   +1 more source

Additional file 3 of Dihydromyricetin inhibits African swine fever virus replication by downregulating toll-like receptor 4-dependent pyroptosis in vitro

open access: yes, 2023
Additional file 3. Cytotoxicity of resatorvid, EUK-134, disulfiram, polyphyllin,and RS 09 TFA toward PAMs. The effects of resatorvid, EUK-134, disulfiram, polyphyllin, and RS 09 TFA on the cellular viability of PAMs were examined using the cell-counting ...
Zebu Song (16536887)   +8 more
core   +1 more source

An enormous Paris polyphylla genome sheds light on genome size evolution and polyphyllin biogenesis [PDF]

open access: yes, 2020
Abstract The monocot family Melanthiaceae with varying genome sizes in a range of 230-fold is an ideal model to study the genome size fluctuation in plants. Its family member Paris genus demonstrates an evolutionary trend of bearing huge genomes characterized by an average c-value ...
Jing Li   +25 more
openaire   +1 more source

Polyphyllin I Alleviates Alcoholic Liver Disease via Modulation of the Phosphodiesterase 6D–Cyclic Guanosine Monophosphate–Protein Kinase G Axis

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Alcoholic liver disease (ALD) is a multifaceted disorder in which oxidative injury, iron‐dependent ferroptosis, steatosis, and inflammation are closely intertwined. Consequently, therapeutic strategies targeting a single pathway often produce limited clinical benefits.
Hongyan Feng   +7 more
wiley   +1 more source

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