Results 51 to 60 of about 22,479,757 (178)
Nasopharyngeal carcinoma (NPC) is a malignant tumor in southern China, and nano Traditional Chinese Medicine (TCM) represents great potential to cancer therapy.
Xian-Yu Bai +8 more
core +1 more source
Polyphyllin VII induces apoptosis in HepG2 cells through ROS-mediated mitochondrial dysfunction and MAPK pathways [PDF]
Polyphyllin VI (PP6) inhibited the proliferation of human cancer cells (HepG2, A549, MCF7, SKOV3, Hep3B, Bel7402 and 7721). Cells were treated with increasing concentrations of PP6 for 24 h and cell viability was determined by MTT assay as described in ...
Shenghui Chen +23 more
core +1 more source
Chemical structures of polyphyllin I, II, VI and VII.
Chemical structures of polyphyllin I, II, VI and VII.
Tianjun Yuan (524010) +8 more
core +1 more source
Bioactive secondary metabolites in Paris polyphylla Sm. and their biological activities: A review
Paris polyphylla Sm. is an important medicinal plant used to treat a variety of diseases through traditional medicine systems such as Ayurveda, Tibetan traditional medicines, Chinese traditional medicines, and others around the world.
Chandra Bahadur Thapa +6 more
doaj +1 more source
Effects of polyphyllin I on growth inhibition of human non-small lung cancer cells and in xenograft [PDF]
Polyphyllin I (PPI), a small molecular monomer extracted from Rhizoma of Paris polyphyllin, shows strong anticancer effects in previous study. Human lung adenocarcinoma A549 cells, human lung squamous cell carcinoma SK-MES-1 cells, and human lung large cell carcinoma H460 cells were cultured and then treated with PPI.
Minjian, Kong +4 more
openaire +2 more sources
The average contents of polyphyllin I, II, VII and total steroid saponins in Paris from different geographical regions: (1) Central Yunnan; (2) Northwestern Yunnan; (3) Southwestern Yunnan; (4) Southeastern Yunnan; (5) Guizhou; (6) Guangxi.
Tianjun Yuan (524010) +8 more
core +1 more source
Blockade of EGFR with reversible EGFR tyrosine kinase inhibitors (TKIs) is considered the frontline strategy for advanced NSCLC with EGFR mutations. However, acquired resistance to EGFR-TKI has been observed, resulting in disease progression and limited ...
Zhenghua Fei, Hao Jiang, Honggang Wang
core +1 more source
Additional file 3. Cytotoxicity of resatorvid, EUK-134, disulfiram, polyphyllin,and RS 09 TFA toward PAMs. The effects of resatorvid, EUK-134, disulfiram, polyphyllin, and RS 09 TFA on the cellular viability of PAMs were examined using the cell-counting ...
Zebu Song (16536887) +8 more
core +1 more source
An enormous Paris polyphylla genome sheds light on genome size evolution and polyphyllin biogenesis [PDF]
Abstract The monocot family Melanthiaceae with varying genome sizes in a range of 230-fold is an ideal model to study the genome size fluctuation in plants. Its family member Paris genus demonstrates an evolutionary trend of bearing huge genomes characterized by an average c-value ...
Jing Li +25 more
openaire +1 more source
ABSTRACT Alcoholic liver disease (ALD) is a multifaceted disorder in which oxidative injury, iron‐dependent ferroptosis, steatosis, and inflammation are closely intertwined. Consequently, therapeutic strategies targeting a single pathway often produce limited clinical benefits.
Hongyan Feng +7 more
wiley +1 more source

