Results 71 to 80 of about 22,479,757 (178)

Plant‐Derived Treatments for Monogenean Parasites in Farmed Fish: A Systematic Review and Meta‐Analysis

Reviews in Aquaculture, Volume 18, Issue 3, June 2026.
ABSTRACT Monogeneans are among the most problematic ectoparasites in finfish aquaculture. Plant‐derived compounds have been widely explored as therapeutic agents, yet their efficacy and safety have not been quantitatively synthesized across studies. This study provides a meta‐analysis of plant‐based treatments against monogeneans, integrating 453 in ...
Francisco Neptalí Morales‐Serna
wiley   +1 more source

Punicalagin Inhibits the Growth and Proliferation of Ovarian Epithelial Adenocarcinoma Cells Via Apoptosis and Autophagic Cell Death

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 5, May 2026.
Punicalagin targets ovarian cancer via multiple anti‐cancer mechanisms. This graphical abstract summarizes the key findings of the study on the effects of Punicalagin (PCG), a pomegranate‐derived polyphenol, on ovarian cancer cells (OVCAR‐3 and SKOV‐3).
Zeeshan Ahmad Bhutta, Cho‐Won Kim, Hwayoung Na, Hong Kyu Lee, Kyung‐Chul Choi   +4 more
wiley   +1 more source

Biomimetic Cell Membrane‐Coated MOFs System for Targeted Cancer Therapy

Advanced Science, Volume 13, Issue 21, 13 April 2026.
Biomimetic MOF‐based drug delivery nanoplatforms synthesized using liposomes or cell membranes as camouflage for multiple cancer therapeutics. ABSTRACT The integration of metal‐organic frameworks (MOFs) with cell membrane coatings has emerged as a revolutionary strategy to enhance the therapeutic efficacy of cancer nanomedicine.
Qilu Wu, Jia Song Deon Chon, Yuxiao Feng, Kang Liang, Shiming Li, Can Yang Zhang, Jun Ge   +6 more
wiley   +1 more source

Rutaceae Zanthoxylum–Derived 7‐Demethylsuberosin Alleviates the Rheumatoid Arthritis Through Inhibiting the Maturation of Dendritic Cells via Targeting MAPK14 Functional Food‐Based 7‐Demethylsuberosin

Food Frontiers, Volume 7, Issue 2, March 2026.
This study revealed that 7‐demethylsuberosin exhibits immunosuppressive effects both in vivo and in vitro. Furthermore, it inhibits the phosphorylation of MAPK14 by targeting it, thereby modulating dendritic cell (DC) maturation and function and reducing inflammation across various in vivo models.
Peng Han, Bo Wang, Luyang Han, Yanbo Zhu, Jiawei Dong, Yuekang Xu, Xiaoying Liu, Jinyao Li   +7 more
wiley   +1 more source

Paridis Rhizoma Saponins ameliorate CCl4-induced liver fibrosis via modulation of the Nrf2-HO-1/NQO-1 and TGF-β1/Smads signaling pathways

Biochemistry and Biophysics Reports
Objective/background: Paridis Rhizoma is a common traditional Chinese medicine (TCM), possessing therapeutic effects including heat-clearing, detoxification, and liver calming effects.
Yan Hong, Shuang Geng, Huihao Ao, Mengya Fu, Xiaojun Yang, Gang Cao, Yanquan Han   +6 more
doaj   +1 more source

Fluorophore-Appended Steroidal Saponin (Dioscin and Polyphyllin D) Derivatives

, 2016
The synthesis of three fluorophore-appended derivatives of dioscin and polyphyllin D is reported herein. Starting from trillin, dansyl derivatives A−C were prepared in overall yields of 7−12% over 7−10 steps.
Zhiqi Yang (2692909), Chi-Ming Che (1268400), Ella Lai-Ming Wong (1958881), Tina Yuen-Ting Shum (2308552), Yongzheng Hui (2692912)   +4 more
core   +1 more source

Probe substrates assay estimates the effect of polyphyllin H on the activity of cytochrome P450 enzymes in human liver microsomes

Pharmacology Research & Perspectives
Cytochrome P450 enzymes (CYPs) play a crucial role in phase I metabolic reactions. The activity of CYPs would affect therapeutic efficacy and may even induce toxicity.
Erhao Wang, Mengxi Wang, Ming Gao
doaj   +1 more source

Paris Polyphylla Inhibits Colorectal Cancer Cells via Inducing Autophagy and Enhancing the Efficacy of Chemotherapeutic Drug Doxorubicin

Molecules, 2019
Colorectal cancer is one of the most common cancers worldwide and chemotherapy is the main approach for the treatment of advanced and recurrent cases. Developing an effective complementary therapy could help to improve tumor suppression efficiency and ...
Liang-Tzung Lin, Wu-Ching Uen, Chen-Yen Choong, Yeu-Ching Shi, Bao-Hong Lee, Cheng-Jeng Tai, Chen-Jei Tai   +6 more
doaj   +1 more source

Dual Roles of Natural Products in Regulating Ferroptosis in Acute and Chronic Liver Diseases: A Review

Oxidative Medicine and Cellular Longevity, Volume 2026, Issue 1, 2026.
Liver diseases, both acute and chronic, are a major global health burden with limited therapeutic options. Ferroptosis, an iron‐dependent form of regulated cell death driven by lipid peroxidation, has emerged as a key contributor to liver pathology and a potential therapeutic target.
Farshad Niazpour, Reza Meshkani, Swaran J. S. Flora   +2 more
wiley   +1 more source

Phorbol Myristate Acetate Inhibits Senecavirus A Replication by Activating IKBKE–Mediated IFN Pathway and NF‐κB Signal

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Senecavirus A (SVA) is an emerging picornavirus causing vesicular disease indistinguishable from foot‐and‐mouth disease virus (FMDV). So far, there are no commercial vaccines and effective therapeutic drugs against SVA infection in China. Here, a library of 112 compounds were screened, and we found that phorbol myristate acetate plays an antagonistic ...
Junfang Yan, Yanni Gao, Chengyi Guo, Yubei Dong, Ping Jiang, Juan Bai, Linzhu Ren   +6 more
wiley   +1 more source