Results 131 to 140 of about 1,949 (187)
Sophoraflavanone G in Nano-Niosomal Form: Implications for Bacterial Inhibition, Biofilm Disruption, and Cancer Suppression. [PDF]
Avicenna J Med BiotechnolTeymouri M +7 more
europepmc +1 more source
The effect of syringe design and cannula dimensions on time-force curve in intravitreal injection across different drug viscosities: area under the curve and peak injection force. [PDF]
Int J Retina VitreousAckermann BC +7 more
europepmc +1 more source
Adsorption of Mixed Micelles of Polysorbate 80 and Oleic Acid to the Air-Water Interface. [PDF]
LangmuirAyati NS +7 more
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The Characterization of Polysorbate
Current Protocols, 2022AbstractPolysorbates (PSs), including PS20 and PS80, are non‐ionic surfactants widely used in the pharmaceutical industry to enhance drug solubility and stability. Despite their wide application, PSs are prone to degradation by either hydrolysis or oxidation in drug formulations during storage; therefore, a PS characterization method assessing protein ...
Sisi, Zhang, Hui, Xiao, Ning, Li
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Journal of Pharmaceutical Sciences, 1978
Aqueous solutions of polysorbate 20 undergo autoxidation on storage, with the peroxide number increasing and subsequently decreasing again, the acidity increasing continuously, the pH and surface tension falling and tending to level off, and the cloud point dropping sharply until turbidity begins at room temperature.
M Donbrow
exaly +3 more sources
Aqueous solutions of polysorbate 20 undergo autoxidation on storage, with the peroxide number increasing and subsequently decreasing again, the acidity increasing continuously, the pH and surface tension falling and tending to level off, and the cloud point dropping sharply until turbidity begins at room temperature.
M Donbrow
exaly +3 more sources
Journal of Pharmaceutical Sciences, 1974
The CMC of a series of polysorbates was determined using a surface tension method. The CMC values obtained did not vary to any appreciable extent from those determined by other techniques, indicating that the procedure adopted was reliable, simple, and fast. The application of the usual correction factors was not necessary in the calculation of the CMC
Lucy S C Wan
exaly +3 more sources
The CMC of a series of polysorbates was determined using a surface tension method. The CMC values obtained did not vary to any appreciable extent from those determined by other techniques, indicating that the procedure adopted was reliable, simple, and fast. The application of the usual correction factors was not necessary in the calculation of the CMC
Lucy S C Wan
exaly +3 more sources
Drug Development and Industrial Pharmacy, 1998
Using the analytical constants for sorbitan monolaurate, monopalmitate, monostearate, and monooleate given in the National Formulary (NF), calculations were carried out that indicated that these emulsifiers are esters of sorbitol mono- and dianhydrides. Contrary to the NF description, no significant amount of sorbitol ester was calculated to be present,
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Using the analytical constants for sorbitan monolaurate, monopalmitate, monostearate, and monooleate given in the National Formulary (NF), calculations were carried out that indicated that these emulsifiers are esters of sorbitol mono- and dianhydrides. Contrary to the NF description, no significant amount of sorbitol ester was calculated to be present,
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Considerations for the Use of Polysorbates in Biopharmaceuticals
Pharmaceutical Research, 2018Polysorbates are commonly added to protein formulations and serve an important function as stabilizers. This paper reviews recent literature detailing some of the issues seen with the use of polysorbate 80 and polysorbate 20 in protein formulations.
Michael T. Jones +14 more
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The determination of polysorbate 60 in foods
Journal of the American Oil Chemists' Society, 1971AbstractAnalytical methods have been developed for the determination of polysorbate 60 (Tween 60, Atlas Chemical Industries, Inc.) in several food products including baked bread and cake, cake mix, yeastraised doughnuts, shortening, foam‐mat dried tomato paste and citrus fruit juices, dressings for salad, and potato flakes.
C F, Smullin +2 more
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