Results 101 to 110 of about 379,805 (312)

Lipid peroxidation is essential for α-synuclein-induced cell death.

open access: yes, 2015
Parkinson's disease is the second most common neurodegenerative disease and its pathogenesis is closely associated with oxidative stress. Deposition of aggregated α-synuclein (α-Syn) occurs in familial and sporadic forms of Parkinson's disease.
Klenerman, D   +5 more
core  

Elongase Gene And Production Of Delta9-polyunsaturated Fatty Acids (Patent US 7601889 B2) [PDF]

open access: yes, 2009
This invention relates to a new elongase gene having the sequence SEQ ID NO: 1 or its derivatives, to a gene construct comprising this sequence or its derivatives and to its use.
Napier, J. A.   +3 more
core  

Efficient and specific analysis of red blood cell glycerophospholipid fatty acid composition. [PDF]

open access: yes, 2012
Red blood cell (RBC) n-3 fatty acid status is related to various health outcomes. Accepted biological markers for the fatty acid status determination are RBC phospholipids, phosphatidylcholine, and phosphatidyletholamine.
Hans Demmelmair   +11 more
core   +1 more source

Unveiling Endotypes in Systemic Lupus Erythematosus Through Multiomic Analysis: Insights Into Cardiovascular and Renal Complications

open access: yesArthritis &Rheumatology, EarlyView.
Objective Systemic lupus erythematosus (SLE) shows clinical and molecular heterogeneity, and cardiovascular (CV) complications and lupus nephritis (LN) remain leading causes of morbidity and mortality. This study investigated whether omic profiling can reveal molecular endotypes linked to these outcomes.
Tomás Cerdó   +84 more
wiley   +1 more source

Beyond the Outburst: Charting a New Frontier for Understanding and Treating Irritability in Autistic Adults

open access: yesAutism Research, EarlyView.
ABSTRACT Irritability is a prevalent and impairing feature associated with autism, yet remains poorly understood, particularly in adults. Drawing heavily on insights translated from pediatric and transdiagnostic literatures, we propose that irritability in autistic individuals often reflects a psychophysiological stress or threat response, rooted in a ...
Hsiang‐Yuan Lin   +3 more
wiley   +1 more source

Transgenic barley producing essential polyunsaturated fatty acids

open access: yes, 2014
Polyunsaturated fatty acids (PUFAs) affect diverse physiological processes and human health. Most cereals are poor in n-3 and n-6 PUFAs. Using biolistics, barley (Hordeum vulgare L. cv.
M. Hudcovicová   +10 more
core   +1 more source

Dietary intake of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) in children - a workshop report. [PDF]

open access: yes, 2010
There is controversy whether children should have a dietary supply of preformed long-chain polyunsaturated n-3 fatty acids EPA and DHA. The aims of the workshop were to review evidence for a possible benefit of a preformed EPA and/or DHA supply, of data ...
Eilander, A.   +20 more
core   +1 more source

Chlorella vulgaris biorefineries: sustainable biofuels and high‐value carbon capture

open access: yesBiofuels, Bioproducts and Biorefining, EarlyView.
Abstract Global reliance on fossil fuels has created urgent economic and environmental challenges, yet large‐scale use of algal biomass remains limited by production costs. Industrial scaling is constrained by inefficient harvesting and the technical challenges of processing recalcitrant cell walls.
Sandyelle Ferreira Alcântara Araújo   +13 more
wiley   +1 more source

The role of cytochrome b 5 fusion desaturases in the synthesis of polyunsaturated fatty acids

open access: yes, 2003
The biosynthetic pathway of polyunsaturated fatty acids (PUFAs) has been the subject of much interest over the last few years. Significant progress has been made in the identification of the enzymes required for PUFA synthesis; in particular, the fatty ...
Sayanova, O. V.   +2 more
core   +1 more source

Biochar‐based fertilizers improve nutrient use efficiency in sunflower grown on a subtropical tidal soil

open access: yesBiofuels, Bioproducts and Biorefining, EarlyView.
Abstract Improving fertilizer use efficiency is essential for reducing environmental pollution, sustaining agricultural production, and maximizing the economic profitability of crop production systems. This study tested the hypothesis that the formulation strategy of biochar‐based fertilizers, rather than nutrient addition alone, is associated with ...
Md. Al‐Amin   +7 more
wiley   +1 more source

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