Results 81 to 90 of about 399,393 (308)

Polyunsaturated fatty acids in mitochondria

open access: yesJournal of Lipid Research, 1962
Fatty acids of mitochrondria from hearts and livers of fresh-water and marine fish, marine birds, fur seal, and from sweet potato have been analyzed by gas-liquid chromatography.
T. Richardson   +3 more
doaj   +1 more source

Vascular dysfunction induced in offspring by maternal dietary fat involves altered arterial polyunsaturated fatty acid biosynthesis

open access: yes, 2012
Nutrition during development affects risk of future cardiovascular disease. Relatively little is known about whether the amount and type of fat in the maternal diet affect vascular function in the offspring.
Masoodi, Mojgan   +37 more
core   +1 more source

Lipidomics Reveals Early Metabolic Changes in Subjects with Schizophrenia: Effects of Atypical Antipsychotics [PDF]

open access: yes, 2013
There is a critical need for mapping early metabolic changes in schizophrenia to capture failures in regulation of biochemical pathways and networks.
Buckley, P   +45 more
core   +2 more sources

Degrading GPX4 via Biomimetic Nanoparticle‐Mediated In Situ Synthesis of Deep‐Learning‐Designed Binder‐Degron Chimeras for Prostate Cancer Therapy

open access: yesAdvanced Science, EarlyView.
A deep‐learning‐designed binder is fused to a combinatorial degron to create a binder‐degron chimera (bdC) that recruits the CUL2‐RING ubiquitin ligase complex. Encapsulation in a prostate‐cancer‐targeted, CD47‐camouflaged nanocarrier enables tumor‐specific in situ bdC expression, triggering GPX4 degradation and ferroptosis, thereby establishing a ...
Si‐Han Zhang   +8 more
wiley   +1 more source

cis‐Carboxylate Enhancement of Mn(III)‐OH Hydrogen Atom Abstraction through PCET Thermodynamics

open access: yesAdvanced Science, EarlyView.
ABSTRACT Manganese(III)‐hydroxo intermediates are proposed as key hydrogen atom abstraction (HAA) species in manganese‐dependent enzymes, yet how first‐sphere carboxylate ligands control their proton‐coupled electron transfer (PCET) thermodynamics remains poorly understood.
Yuri Lee   +4 more
wiley   +1 more source

Ciliary Membrane Lipid Homeostasis in Health and Disease

open access: yesAdvanced Science, EarlyView.
This review systematically delineates the distinct lipid landscapes of ciliary membranes, including the spatial organization of phosphoinositides, cholesterol, and sphingolipids. It elucidates how these lipids orchestrate ciliogenesis, signal transduction, and membrane dynamics in cilia beating, and highlights how their dysregulation drives ...
Zhenzhou Huang   +3 more
wiley   +1 more source

STUDIUL ASPECTELOR BIOTEHNOLOGICE DE UTILIZARE A ALGEI ROŞII PORPHYRIDIUM CRUENTUM (Näg) CNM-AR-01 ÎN CALITATE DE SURSĂ DE ACID EICOSAPENTAENOIC

open access: yesStudia Universitatis Moldaviae: Stiinte reale si ale naturii, 2008
Polyunsaturated fatty acids (eicosapentaenoic and arachidonic acids) are investigated for the use of it in food and pharmaceutical industries. Microalgae Porphyridium cruentum CNM-AR-01 strain is one of the potential sources of polyunsaturated fatty ...
USM ADMIN
doaj  

Biobehavioural and cerebral hemodynamic effects of omega-3 polyunsaturated fatty acids in healthy individuals [PDF]

open access: yes
The omega-3 polyunsaturated fatty acids (n-3 PUFAs) are a unique class of fatty acids that cannot be manufactured by the body, and must be acquired via dietary sources.
Jackson, Philippa
core  

Magnetoreceptor Promotes Hepatocellular Carcinoma Development and Blunts Sorafenib‐Induced Ferroptosis by Regulating Iron Homeostasis

open access: yesAdvanced Science, EarlyView.
Magnetoreceptor (MagR) regulates iron homeostasis and mitochondrial function in hepatocellular carcinoma (HCC) cells. Specifically, MagR deficiency suppresses tumor cell proliferation, migration, and invasion and enhances sorafenib‐induced ferroptosis through iron accumulation.
Tao Wang   +13 more
wiley   +1 more source

Association between polyunsaturated fatty acid intake and proteinuria in the US adult population: a study from the NHANES database

open access: yesBMC Urology
Background Moderate consumption of polyunsaturated fatty acids has been shown to confer a protective effect against proteinuria and to slow the progression of chronic kidney disease.
Hao Zhang, Qi Yu Zeng, Ping Zhang
doaj   +1 more source

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