Results 61 to 70 of about 379,805 (312)

Autoxidation Products of Polyunsaturated Galactolipids

Agricultural and Biological Chemistry, 1983
Neat monogalactosyldilinolenoylglycerol (di-18:3 MGDG) and digalactosyldilinolenoylgly- cerol (di-18:3 DGDG) were autoxidized at 37°C. The rate of autoxidation of di-18:3 MGDG was greater than that of di-18:3 DGDG. The oxidation products were separated from unoxidized di- 18:3 MGDG and di-18:3 DGDG by reverse-phase high performance liquid ...
YAMAUCHI, Ryo, KOJIMA, Masahiro, KATO, Koji, UENO, Yoshimitsu   +3 more
openaire   +2 more sources

Mitochondrial Carrier SLC25A13 Drives Ferroptosis Resistance and Immune Evasion via a STAT3–IFI6 Circuit in Breast Cancer

Advanced Science, EarlyView.
SLC25A13 is identified as an immunometabolic driver of triple‐negative breast cancer that sustains ferroptosis resistance and immune evasion through a STAT3–IFI6 circuit. Pharmacologic degradation of SLC25A13 restores ferroptosis sensitivity and enhances anti‐PD‐1 efficacy, highlighting a strategy to convert immune‐cold tumors into immunotherapy ...
Yingze Zhu, Yuhan Tang, Yingcui Chen, Zhuoqi Zhang, Yige Lu, Xinyue Wang, Qiyuan Shi, Wenhui Zhao, Hui Pang   +8 more
wiley   +1 more source

Analysis of the Cochrane Review: Omega-3 Fatty Acids for the Treatment of Dementia. Cochrane Database Syst Rev. 2016;4:CD009002.

Acta Médica Portuguesa, 2017
Dietary supplementation with omega-3 polyunsaturated fatty acids from fish and plant sources is commonly prescribed as a nonfarmacological alternative to improve brain functions and slow down the progression of dementia.
David Cordeiro Sousa, Guilherme Ferreira Dos SANTOS, João Costa, António Vaz-Carneiro   +3 more
doaj   +1 more source

A role for polyunsaturated fatty acids in Th1-mediated disease [PDF]

, 2008
The anti-inflammatory effects of polyunsaturated fatty acids (PUFA) have been well documented, however their exact method of action remains elusive. Dendritic cells (DC) are the most potent antigen presenting cell (APC) and we found that n-3 and n-6 PUFA
Draper, Eve
core  

MiR‐940 Suppresses Ferroptosis by Controlling Expression of Key Regulatory Genes

Advanced Science, EarlyView.
A CRISPR‐based screening identified miR‐940 as a critical suppressor of ferroptosis in cancer. By coordinating the downregulation of pro‐ferroptotic genes with the upregulation of GPX4, miR‐940 establishes a regulatory network that protects against ferroptosis and correlates with poor clinical outcomes in distinct cancer entities.
Andrea Kolak, Juliane Tschuck, Stefanie A. I. Weiß, Daniel Kaemena, Karolin Klimm, Ana Galhoz, Larissa Ringelstetter, Myles Fennell, Juliane Merl‐Pham, Anna Artati, Stefanie Strasser, Ralph Garippa, Michael Witting, Hans Zischka, Joel A. Schick, Stefanie M. Hauck, Michael P. Menden, Michelle Vincendeau, Brent R. Stockwell, Kamyar Hadian   +19 more
wiley   +1 more source

CEBPG‐Mediated Palmitic Acid Adaptation of Cancer‐Associated Fibroblasts Drives Metastasis of Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
This study reveals a metabolic signaling axis in the OSCC microenvironment where palmitic acid (PA) drives the activation of CAFs. PA uptake triggers CEBPG‐dependent epigenetic remodeling to upregulate ERN1 and TMBIM6, thereby mitigating ER stress. This adaptive program sustains CAF survival and the pro‐metastatic phenotype, establishing this pathway ...
Yiling Duan, Yitong Li, Yufei Wu, Xiao Yang, Rui Li, Hui Zhao, Zhengjun Shang   +6 more
wiley   +1 more source

Comparison of fatty acid profiles of sacha inchi oil (Plukenetia huayllabambana), sesame oil (Sesamum indicum), and peanut oil (Arachis hypogaea) using two extraction methods for food purposes

Revista de la Facultad de Ciencias Agrarias
Vegetable oil consumption has increased in recent decades due to the high content of monounsaturated (Omega 9) and polyunsaturated (Omega 3 and 6) fatty acids.
Jhoan Plua Montiel, Juan Alejandro Neira Mosquera, Sungey Naynee Sanchez Llaguno, Jhonnatan Placido Aldas Morejon, Karol Yannela Revilla Escobar, Edgar Caicedo-Álvarez   +5 more
doaj   +2 more sources

Dietary Polyunsaturated Fat and Hypertension

Annals of Medicine, 1989
A significant reduction in blood pressure has been observed during low-fat high poly unsaturated fattyacids/saturated fattyacid--ratio diets in a series of studies conducted in the U.S. and Finland. The results suggest the active role of linoleic acid but the effects of decreased intake of saturated fats and the concomitant changes in the intake of ...
J M, Iacono, R M, Dougherty, P, Puska, P, Pietinen   +3 more
openaire   +2 more sources

Breastfeeding, the use of docosahexaenoic acid-fortified formulas in infancy and neuropsychological function in childhood

, 2010
Objective: To investigate the relation between breastfeeding, use of docosahexaenoic acid (DHA)-fortified formula and neuropsychological function in children. Design Prospective cohort study. Setting Southampton, UK.
West, C, West, Carolyn, Gale, CR, Limond, Jennifer, Gale, Catharine R., Gale, Catherine R., Martyn, CN, Cooper, Cyrus, Robinson, Sian M., Limond, J, Marriott, Lynne D., Marriott, LD, Inskip, HM, Godfrey, Keith M., Law, Catherine M, Law, CM, Inskip, Hazel M, Martyn, Christopher N., Godfrey, KM, Martyn, Christopher N, Marriott, Lynne D, Inskip, Hazel M., Godfrey, Keith M, Robinson, SM, ?, ?, Robinson, Siân M, Cooper, C   +26 more
core   +1 more source

A Modular PLUG‐IN Photosynthetic Chassis With Tunable Thermal Control for Mammalian Systems

Advanced Science, EarlyView.
This work establishes a “plug‐in” chassis compatible with mammalian systems that synchronizes growth, production, and cell‐wall re‐configuration, providing a versatile platform for photosynthetic bioproduction and microalgal synthetic biology. ABSTRACT Microalgae are promising photosynthetic platforms for high‐value compounds, yet their industrial use ...
Qinhua Gan, Zheng Li, Yunfei Chen, Mingting Du, Qianyi Wu, Congcong Miao, Tao Xu, Shan Wu, Xitao Chen, Xingwei Huang, Yuhui Cheng, Chengcheng Li, Yi Xin, Yandu Lu   +13 more
wiley   +1 more source