Results 111 to 120 of about 185,780 (190)

Targeting SHMT2‐mediated membrane phospholipid remodeling for enhanced anti‐GCSCs treatment

Interdisciplinary Medicine, EarlyView.
Depletion of serine via serine hydroxymethyltransferase‐2 (SHMT2) knockdown in gastric cancer (GC) disrupted the maintenance of gastric cancer stem cell stemness by inducing membrane phospholipid remodeling and aberrant CD44 shedding within membrane lipid rafts. The synthesized HA‐Exo‐si SHMT2 demonstrated enhanced therapeutic efficacy and safety in GC.
Liping Yang, Fangli Liao, Yanran Tong, Tong Huang, Yan‐e Du, Siyang Wen, Linshan Jiang, Lanlang Peng, Hua Sun, Gaoli Zhang, Weixian Chen   +10 more
wiley   +1 more source

The prognostic and therapeutic significance of polyunsaturated fatty acid-derived oxylipins in ST-segment elevation myocardial infarction. [PDF]

Imeta
Du Z, Lu Y, Ma Y, Yang Y, Luo W, Liu S, Zhang M, Wang Y, Li L, Li C, Wang W, Gao H.   +11 more
europepmc   +1 more source

Applications of bioactive herbal extracts in dressing materials for skin wound repair: Ingredients, mechanisms and innovations

Interdisciplinary Medicine, EarlyView.
Abstract The skin, as the body's largest organ, plays essential roles in protection, immune regulation, and homeostasis. Skin trauma, especially chronic wounds such as diabetic ulcers, poses significant clinical challenges. Traditional treatments, while often effective, can be costly and pose risks.
Boxiang Yang, Jingyuan Xu, Siyi Liu, Chaoying Wu, Yi Li, Mingqi Lv, Tingting Chen, Chuanrong Zhao, Daojun Pu, Chaojun Tang, Anna Malashicheva, Guangchao Zang, Guixue Wang   +12 more
wiley   +1 more source

Depression in Diarrhea-Predominant IBS Patients: Exploring the Link Between Gut Barrier Dysfunction and Erythrocyte Polyunsaturated Fatty Acid Levels. [PDF]

J Clin Med
Linsalata M, Prospero L, Ignazzi A, Riezzo G, D'Attoma B, Mallardi D, Goscilo F, Notarnicola M, De Nunzio V, Pinto G, Russo F.   +10 more
europepmc   +1 more source

Essential fatty acid deficiency, olive oil‐based intravenous lipid emulsion, and genetic polymorphisms: A pediatric randomized controlled trial

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives There is a concern that decreasing soybean oil (SO) content in intravenous lipid emulsions (ILEs) may increase the risk for essential fatty acid deficiency (EFAD). This study evaluates the risk of EFAD in pediatric patients who were expected to require parenteral nutrition for at least 7 days with an 80% olive oil/20% SO ILE (OO/SO ...
Cynthia Blanco, Weili Chang, Abhay J. Bhatt, Erick Gerday, Ajay J. Talati, Narendra Dereddy, Rachana Singh, Erika Ryan, Thibault Senterre   +8 more
wiley   +1 more source

Ketogenesis supports hepatic polyunsaturated fatty acid homeostasis via fatty acid elongation. [PDF]

Sci Adv
Queathem ED, Moazzami Z, Stagg DB, Nelson AB, Fulghum K, Hayir A, Seay A, Gillingham JR, d'Avignon DA, Han X, Ruan HB, Crawford PA, Puchalska P.   +12 more
europepmc   +1 more source

Effects of microbiota‐based interventions on depression and anxiety in children and adolescents—A systematic review

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract This study aims to systematically review evidence on gut microbiota‐based interventions for reducing depression‐ and anxiety‐like symptoms in children and adolescents with autism spectrum disorder, irritable bowel syndrome, Prader‐Willi syndrome, below‐average literacy skills or anorexia nervosa, where some individuals may exhibit indicators ...
Jiayu Hu, Yan Zhang, Chuwen Liu, Antigone Gkaravella, Jinyue Yu   +4 more
wiley   +1 more source

Dietary Polyunsaturated Fatty Acid Deficiency Impairs Renal Lipid Metabolism and Adaptive Response to Proteinuria in Murine Renal Tubules. [PDF]

Nutrients
Wang Y, Diao P, Aomura D, Nimura T, Harada M, Jia F, Nakajima T, Tanaka N, Kamijo Y.   +8 more
europepmc   +1 more source

Gluten‐free breadsticks with Ganoderma‐fermented corncobs: technological and nutritional features

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Background This study investigates the use of corncobs before and after fermentation with Ganoderma annularis (G) to enhance the nutritional value of gluten‐free breadsticks. Medicinal mushrooms are known to increase the nutrient profile of substrates through solid‐state fermentation (SSF); nevertheless, using the entire SSF – as adopted in ...
Carola Cappa, Giulia Castorina, Giovanni Fiorillo, Maria Cristina Casiraghi, Manuela Rollini, Gabriella Consonni, Daniela Erba, Noemi Negrini, Alessandra Marti   +8 more
wiley   +1 more source

Association between polyunsaturated fatty acid intake and estradiol levels among U.S. women. [PDF]

Front Nutr
Guo L, Nan Y, Liang K, Yao L, Li J.
europepmc   +1 more source