Results 131 to 140 of about 189,310 (233)

AZGP1 in POMC neurons modulates energy homeostasis and metabolism through leptin-mediated STAT3 phosphorylation

Nature Communications
Zinc-alpha2-glycoprotein (AZGP1) has been implicated in peripheral metabolism; however, its role in regulating energy metabolism in the brain, particularly in POMC neurons, remains unknown. Here, we show that AZGP1 in POMC neurons plays a crucial role in
Sheng Qiu, Qinan Wu, Hao Wang, Dongfang Liu, Chen Chen, Zhiming Zhu, Hongting Zheng, Gangyi Yang, Ling Li, Mengliu Yang   +9 more
doaj   +1 more source

The effect of bisphenol A on pro-opiomelanocortin and circadian clock gene expression in POMC-expressing hypothalamic neuronal models [PDF]

, 2018
Bisphenol A (BPA) has been linked to obesity. However, the direct effect of BPA on hypothalamic pro-opiomelanocortin (POMC) neurons, which regulate energy homeostasis, remains unexplored. We describe here the effect of BPA on immortalized POMC-expressing
Salehi, Ashkan
core  

POMC Is Expressed in Pancreatic Alpha Cells [PDF]

, 2012
Pancreatic alpha cells secrete glucagon to increase blood glucose during hypoglycemia. Currently, the mechanisms that initiate glucagon secretion are not well understood.
Farrara, Samia M.M
core  

Systemic POMC Overexpression Increases Visceral Fat Accumulation in Mice

, 2011
Proopiomelanocortin (POMC) is a polypeptide precursor with 241 amino acid residues which undergoes extensive post-translational modification to yield a range of smaller, biological active peptides including \uce\ub1-, \uce\ub2 -, \uce\ub3-melanocyte ...
Tang, Chia-Hua
core  

POMC [PDF]

, 2019
openaire   +1 more source

Hypothalamic POMC Neurons Gate the Fear-Feeding Trade-Off. [PDF]

Adv Sci (Weinh)
Miralpeix C, Eraso-Pichot A, Simon V, Jouque V, Sadallah M, Clark S, Zizzari P, Skupio U, Covelo A, Dupuy N, Nicolas JC, Cannich A, Leste-Lasserre T, Laplagne G, Quarta C, Marsicano G, Cota D.   +16 more
europepmc   +1 more source

POMC Gene [PDF]

, 2020
openaire   +1 more source

Deletion of α7 Nicotinic Acetylcholine Receptor in POMC Neurons Impairs Energy Balance and Leptin-Induced Anorexigenic Response in Male Mice. [PDF]

Int J Mol Sci
Chaves WF, Costa SO, Costa CL, Lopes PKF, da Silva IM, Martins ÍCA, Milanski M, Ignácio de Souza LM, Torsoni AS, da Silva Aragão R, Torsoni MA.   +10 more
europepmc   +1 more source

POMC AMPKα1 deletion drives male-specific BAT thermogenesis and obesity resistance. [PDF]

EMBO Rep
Freire-Agulleiro Ó, Rios Garcia M, Ferreira V, Seoane-Collazo P, Roa J, Estévez-Salguero Á, Otero-Rey A, Capellades J, Ruiz-Pino F, Garrido-Gil P, Simon V, Nicolas JC, López JA, Contreras C, Liñares-Pose L, Gonzalez F, Labandeira-García JL, Vázquez J, Diéguez C, Nogueiras R, Cota D, Yanes O, Sabio G, Tena-Sempere M, Quarta C, González-García I, López M.   +26 more
europepmc   +1 more source

Human Epidermal Proopiomelanocortin (POMC) cDNA Variant is Identical to Mouse POMC cDNA [PDF]

Journal of Investigative Dermatology, 1999
Ancans, Janis, Thody, Anthonny J., Wood, John M., Beazley, Wayne D., Schallreuter, Karin U.   +4 more
openaire   +1 more source