Results 61 to 70 of about 41,053 (237)

Somatostatin agonist pasireotide inhibits exercise stimulated growth in the male Siberian hamster (Phodopus sungorus) [PDF]

open access: yes, 2017
R.Dumbell was supported by a University of Aberdeen PhD studentship and a research visit grant awarded by the British Society of Neuroendocrinology. Further support was provided by the Scottish Government Rural and Environment Science and Analytical ...
Barrett, P   +6 more
core   +2 more sources

Activation of temperature-sensitive TRPV1-like receptors in ARC POMC neurons reduces food intake. [PDF]

open access: yesPLoS Biology, 2018
Proopiomelanocortin (POMC) neurons in the arcuate nucleus of the hypothalamus (ARC) respond to numerous hormonal and neural signals, resulting in changes in food intake.
Jae Hoon Jeong   +5 more
doaj   +1 more source

Differential contribution of POMC and AgRP neurons to the regulation of regional autonomic nerve activity by leptin

open access: yesMolecular Metabolism, 2018
Objectives: The autonomic nervous system is critically involved in mediating the control by leptin of many physiological processes. Here, we examined the role of the leptin receptor (LepR) in proopiomelanocortin (POMC) and agouti-related peptide (AgRP ...
Balyssa B. Bell   +4 more
doaj   +1 more source

Activity Based Anorexia as an Animal Model for Anorexia Nervosa–A Systematic Review [PDF]

open access: yes, 2019
Anorexia nervosa (AN) is a severe eating disorder affecting around 1 per 100 persons. However, the knowledge about its underlying pathophysiology is limited.
Schalla, Martha A., Stengel, Andreas
core   +1 more source

Hypothalamic Proopiomelanocortin Is Necessary for Normal Glucose Homeostasis in Female Mice

open access: yesFrontiers in Endocrinology, 2018
The arcuate nucleus of the hypothalamus is a key regulator of energy balance and glucose homeostasis. In particular, arcuate proopiomelanocortin (POMC) neurons inhibit food intake, stimulate energy expenditure and increase glucose tolerance.
Ramiro Alsina   +3 more
doaj   +1 more source

From obesity resistance to obesity prediction and prevention? [PDF]

open access: yes, 2016
Comment on: Regulation of hypothalamic neuropeptides gene expression in diet induced obesity resistant rats: possible targets for obesity prediction?
Cassano, Tommaso, Gaetani, Silvana
core   +6 more sources

mTORC1-dependent increase in oxidative metabolism in POMC neurons regulates food intake and action of leptin

open access: yesMolecular Metabolism, 2018
Objective: Nutrient availability modulates reactive oxygen species (ROS) production in the hypothalamus. In turn, ROS regulate hypothalamic neuronal activity and feeding behavior.
Magalie Haissaguerre   +9 more
doaj   +1 more source

Over-expression of leptin receptors in hypothalamic POMC neurons increases susceptibility to diet-induced obesity. [PDF]

open access: yesPLoS ONE, 2012
Diet-induced obesity (DIO) in rodents is characterized by impaired activation of signal-transducer and activator of transcription 3 (STAT3) by leptin receptors (LepRb) within the hypothalamic arcuate nucleus.
Kevin M Gamber   +5 more
doaj   +1 more source

Augmented Hypothalamic Corticotrophin-Releasing Hormone mRNA and Corticosterone Responses to Stress in Adult Rats Exposed to Perinatal Hypoxia [PDF]

open access: yes, 2007
Stressful events before or just after parturition alter the subsequent phenotypical response to stress in a general process termed programming. Hypoxia during the period before and during parturition, and in the postnatal period, is one of the most ...
Cullinan, William E   +2 more
core   +2 more sources

Heterogeneity of hypothalamic pro-opiomelanocortin-expressing neurons revealed by single-cell RNA sequencing

open access: yesMolecular Metabolism, 2017
Objective: Arcuate proopiomelanocortin (POMC) neurons are critical nodes in the control of body weight. Often characterized simply as direct targets for leptin, recent data suggest a more complex architecture.
Brian Y.H. Lam   +14 more
doaj   +1 more source

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