Results 61 to 70 of about 145,891 (201)

Soluplus solutions as thermothickening materials for topical drug delivery. [PDF]

open access: yes, 2019
Soluplus is a pharmaceutical excipient used primarily in the manufacture of solid dispersions. The polymer also exhibits interesting rheology in aqueous solution, increasing in viscosity as the solution is warmed.
Abou Shamat, Mohamad, Cook, Michael
core   +2 more sources

Study of dissolution rate enhancement of poorly water soluble drug [PDF]

open access: yes, 2008
Aim of this work is the preparation of spray-dried microspheres as drug delivery systems for Rokitamycin (RK), using chitosan (C) and its salt, chitosan glutamate (CG) to improve the dissolution rate of the drug.
Gavini, Elisabetta   +3 more
core  

Can biorelevant media be simplified by using SLS and tween 80 to replace bile compounds? [PDF]

open access: yes, 2013
In the scientific literature, the use of a surfactant is recommended for both designing quality control tests for water insoluble or sparingly water soluble drugs and for predicting the bioavailability of drugs from various types of formulations.
Klein, Sandra, Taupitz, Thomas
core  

Preparation And Evaluation Of Fenofibrate-Gelucire 44/14 Solid Dispersions [PDF]

open access: yes, 2007
Potensi formulasi berasaskan sebaran pepejal menggunapakai Gelucire 44/14 sebagai pembawa untuk meningkatkan pelarutan serta biokeperolehan oral fenofibrat, sejenis drug yang tak mudah larut, telah disiasat.
Al-Dhalli, Samer
core   +1 more source

Curcumin-loaded zeolite as anticancer drug carrier: Effect of curcumin adsorption on zeolite structure [PDF]

open access: yes, 2020
In this work we used a combination of different techniques to investigate the adsorption properties of curcumin by zeolite type A for potential use as an anticancer drug carrier.
Ahali Abadeh, Z.   +3 more
core   +1 more source

Improved dissolution of Kaempferia parviflora extract for oral administration by preparing solid dispersion via solvent evaporation

open access: yesAsian Journal of Pharmaceutical Sciences, 2017
Kaempferia parviflora, a plant in the family Zingiberaceae, has been used in Thai traditional medicines for treating hypertension and promoting longevity with good health and well-being.
Yotsanan Weerapol   +3 more
doaj   +1 more source

Formulation of itraconazole nanococrystals and evaluation of their bioavailability in dogs [PDF]

open access: yes, 2014
The aim of the study is to increase the bioavailability of itraconazole (ITRA) using nanosized cocrystals prepared via wet milling of ITRA in combination with dicarboxylic acids.
Adriaensens, Peter   +7 more
core   +1 more source

Antisolvent Crystallization of Poorly Water Soluble Drugs

open access: yesInternational Journal of Chemical Engineering and Applications, 2013
The enhancement in bioavailability of the drugs is one of the most important concerning aspects of the pharmaceutical industries. Preparation of nanoparticles or microparticles of these drugs is the newest formulation strategies. The size and morphology of a drug are affecting several essential pharmaceutical properties.
Abhijit A. Lonare, Sanjaykumar R. Patel
openaire   +1 more source

Crosslinked hydrogels—a promising class of insoluble solid molecular dispersion carriers for enhancing the delivery of poorly soluble drugs

open access: yesActa Pharmaceutica Sinica B, 2014
Water-insoluble materials containing amorphous solid dispersions (ASD) are an emerging category of drug carriers which can effectively improve dissolution kinetics and kinetic solubility of poorly soluble drugs.
Dajun D. Sun, Ping I. Lee
doaj   +1 more source

Solid crystal suspension of Efavirenz using hot melt extrusion: exploring the role of crystalline polyols in improving solubility and dissolution rate [PDF]

open access: yes, 2017
The poor aqueous solubility of drugs has emerged as a major issue for pharmaceutical scientists from many decades. The current study explores the manufacture and development of a thermodynamically stabilized solid crystal suspension (SCS) of poorly water
Amin, Purnima D   +3 more
core   +1 more source

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