Soluplus solutions as thermothickening materials for topical drug delivery. [PDF]
Soluplus is a pharmaceutical excipient used primarily in the manufacture of solid dispersions. The polymer also exhibits interesting rheology in aqueous solution, increasing in viscosity as the solution is warmed.
Abou Shamat, Mohamad, Cook, Michael
core +2 more sources
Study of dissolution rate enhancement of poorly water soluble drug [PDF]
Aim of this work is the preparation of spray-dried microspheres as drug delivery systems for Rokitamycin (RK), using chitosan (C) and its salt, chitosan glutamate (CG) to improve the dissolution rate of the drug.
Gavini, Elisabetta +3 more
core
Can biorelevant media be simplified by using SLS and tween 80 to replace bile compounds? [PDF]
In the scientific literature, the use of a surfactant is recommended for both designing quality control tests for water insoluble or sparingly water soluble drugs and for predicting the bioavailability of drugs from various types of formulations.
Klein, Sandra, Taupitz, Thomas
core
Preparation And Evaluation Of Fenofibrate-Gelucire 44/14 Solid Dispersions [PDF]
Potensi formulasi berasaskan sebaran pepejal menggunapakai Gelucire 44/14 sebagai pembawa untuk meningkatkan pelarutan serta biokeperolehan oral fenofibrat, sejenis drug yang tak mudah larut, telah disiasat.
Al-Dhalli, Samer
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Curcumin-loaded zeolite as anticancer drug carrier: Effect of curcumin adsorption on zeolite structure [PDF]
In this work we used a combination of different techniques to investigate the adsorption properties of curcumin by zeolite type A for potential use as an anticancer drug carrier.
Ahali Abadeh, Z. +3 more
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Kaempferia parviflora, a plant in the family Zingiberaceae, has been used in Thai traditional medicines for treating hypertension and promoting longevity with good health and well-being.
Yotsanan Weerapol +3 more
doaj +1 more source
Formulation of itraconazole nanococrystals and evaluation of their bioavailability in dogs [PDF]
The aim of the study is to increase the bioavailability of itraconazole (ITRA) using nanosized cocrystals prepared via wet milling of ITRA in combination with dicarboxylic acids.
Adriaensens, Peter +7 more
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Antisolvent Crystallization of Poorly Water Soluble Drugs
The enhancement in bioavailability of the drugs is one of the most important concerning aspects of the pharmaceutical industries. Preparation of nanoparticles or microparticles of these drugs is the newest formulation strategies. The size and morphology of a drug are affecting several essential pharmaceutical properties.
Abhijit A. Lonare, Sanjaykumar R. Patel
openaire +1 more source
Water-insoluble materials containing amorphous solid dispersions (ASD) are an emerging category of drug carriers which can effectively improve dissolution kinetics and kinetic solubility of poorly soluble drugs.
Dajun D. Sun, Ping I. Lee
doaj +1 more source
Solid crystal suspension of Efavirenz using hot melt extrusion: exploring the role of crystalline polyols in improving solubility and dissolution rate [PDF]
The poor aqueous solubility of drugs has emerged as a major issue for pharmaceutical scientists from many decades. The current study explores the manufacture and development of a thermodynamically stabilized solid crystal suspension (SCS) of poorly water
Amin, Purnima D +3 more
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