Results 31 to 40 of about 521,449 (181)
The restriction of zoonotic PERV transmission by human APOBEC3G. [PDF]
PLoS ONE, 2007 The human APOBEC3G protein is an innate anti-viral factor that can dominantly inhibit the replication of some endogenous and exogenous retroviruses. The prospects of purposefully harnessing such an anti-viral defense are under investigation.
Stefán R Jónsson +5 more
doaj +1 more source
Vaccination against the Koala Retrovirus (KoRV): Problems and Strategies
Animals, 2021 The koala retrovirus (KoRV) is spreading in the koala population from the north to the south of Australia and is also in the process of endogenization into the koala genome.
Joachim Denner
doaj +1 more source
Porcine Endogenous Retrovirus Induces CXCL10 in Human Monocytes and Monocyte-Derived Primary Cells
Intervirology, 2022 Introduction: Pigs are suitable donor species for xenotransplantation and biological materials from these animals are used for this purpose for many years.
Hussein Al-Shehabi, Norbert Bannert
doaj +1 more source
Inhibition of budding/release of porcine endogenous retrovirus [PDF]
Microbiology and Immunology, 2014 AbstractPERV is integrated into the genome of all pigs. PERV‐A and PERV‐B are polytropic and can productively infect human cell lines, whereas PERV‐C is ecotropic. Recombinant PERV‐A/C can infect human cells and exhibits high titer replication. Therefore, use of pigs for human xenotransplantation raises concerns about the risks of transfer of this ...
Masumi, Abe +4 more
openaire +2 more sources
Evidence and Consequence of Porcine Endogenous Retrovirus Recombination [PDF]
Journal of Virology, 2004 ABSTRACT The genetic nature and biological effects of recombination between porcine endogenous retroviruses (PERV) were studied. An infectious molecular clone was generated from a high-titer, human-tropic PERV isolate, PERV-A 14/220 (B. A. Oldmixon, et al. J. Virol. 76: 3045-3048, 2002; T. A.
Birke, Bartosch +5 more
openaire +2 more sources
Endogenous betaretroviruses of sheep: teaching new lessons in retroviral interference and adaptation [PDF]
, 2004 The endogenous betaretroviruses of small ruminants offer an excellent model to investigate the biological relevance of endogenous retroviruses (ERVs). Approximately twenty copies of endogenous betaretroviruses (enJSRVs) are present in the genome of sheep
Palmarini, M. +3 more
core +2 more sources
Sensitive detection systems for infectious agents in xenotransplantation*
Xenotransplantation, EarlyView., 2020 Abstract Xenotransplantation of pig cells, tissues, or organs may be associated with transmission of porcine microorganisms, first of all of viruses, to the transplant recipient, potentially inducing a disease (zoonosis). I would like to define detection systems as the complex of sample generation, sample preparation, sample origin, time of sampling ...
Joachim Denner
wiley +1 more source
Detection and Characterization of Porcine Endogenous Retrovirus in Porcine Plasma and Porcine Factor VIII [PDF]
Journal of Virology, 2001 ABSTRACT The pig genome contains porcine endogenous retroviruses (PERVs) capable of infecting human cells. Detection of infectious retrovirus in porcine peripheral blood mononuclear cells and endothelial cells suggested to us that pig plasma is likely to contain PERV.
D M, Takefman +4 more
openaire +2 more sources
Frontiers in Genetics, 2022 Long noncoding RNAs (lncRNAs) are increasingly being recognized as modulators of early embryonic development in mammals. However, they are seldom investigated in pigs.
Xu Yang +5 more
doaj +1 more source
Extended Analysis of the In Vitro Tropism of Porcine Endogenous Retrovirus [PDF]
Journal of Virology, 2000 ABSTRACTWe previously reported that mitogenic activation of porcine peripheral blood mononuclear cells resulted in production of porcine endogenous retrovirus(es) (PERV[s]) capable of productively infecting human cells (C. Wilson et al., J. Virol. 72:3082–3087, 1998).
C A, Wilson +3 more
openaire +2 more sources