Results 131 to 140 of about 517,815 (166)

Epigenetic mechanisms of retroviral regulation: a comparative review. [PDF]

open access: yesEpigenetics Chromatin
Shin SY   +3 more
europepmc   +1 more source

Phase separation of DUX family proteins drives totipotent-like state via 3D genome reorganization and retrotransposon activation. [PDF]

open access: yesProtein Cell
Gao L   +14 more
europepmc   +1 more source

Present Advances and Emerging Challenges in Kidney Xenotransplantation. [PDF]

open access: yesJ Clin Med
Yamanaka K   +10 more
europepmc   +1 more source

Liver Xenotransplantation: Ethical and Societal Implications. [PDF]

open access: yesXenotransplantation
Hurst DJ   +4 more
europepmc   +1 more source

Porcine endogenous retroviruses in xenotransplantation

open access: yesNephrology Dialysis Transplantation
ABSTRACT Xenotransplantation using pig cells, tissues or organs is under development to alleviate the shortage of human donor organs. Meanwhile, remarkably long survival times of pig organs in non-human primates have been reported, as well as the functionality of pig kidneys and hearts in brain-dead humans.
Joachim Denner
exaly   +3 more sources

The origin of porcine endogenous retroviruses (PERVs)

Archives of Virology, 2021
Porcine endogenous retroviruses (PERVs) are integrated in the genome of all pigs, and they produce viral particles that are able to infect human cells and therefore pose a special risk for xenotransplantation. In contrast to other pig microorganisms that also pose a risk, such as porcine cytomegalovirus and hepatitis E virus, PERVs cannot be eliminated
openaire   +2 more sources

APOBEC3 Proteins and Porcine Endogenous Retroviruses

Transplantation Proceedings, 2008
Xenotransplantation of porcine cells, tissues, and organs offers a solution to overcome the shortage of human donor materials. In addition to the immunological and physiological barriers, the existence of numerous porcine microorganisms including viruses poses a risk for xenozoonosis.
E, Dörrschuck, C, Münk, R R, Tönjes
openaire   +2 more sources

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