Results 101 to 110 of about 1,247 (177)

Distribution of porcine endogenous retroviruses (PERVs) DNA in organs of a domestic pig.

Annals of transplantation, 2005
Domestic pig may serve as the most appropriate organ source for human xenotransplantation in the future. However, there is a serious threat of xenogeneic pathogens transmission, especially porcine endogenous retroviruses (PERVs) which are present in genomes of all pigs. The aim of this study was to monitor the prevalence and distribution of PERV DNA in
Daniel, Sypniewski, Grzegorz, Machnik, Urszula, Mazurek, Tadeusz, Wilczok, Zdzisław, Smorag, Jacek, Jura, Barbara, Gajda   +6 more
openaire   +1 more source

Distribution Of Porcine Endogenous Retrovirus (PERV) Variants In Domestic And Feral Pig [PDF]

, 2018
Xenotransplantation is considered an alternative to allotransplantation to relieve the current shortage of human organs. Due to their similar size and physiology, the organs of pigs are of particular interest for this purpose. Endogenous retroviruses are
Acharya, Rashmi
core   +1 more source

Is it currently possible to evaluate the risk posed by PERVs for clinical xenotransplantation? [PDF]

, 2018
Denner, Joachim, Schuurman, Henk-Jan, Scobie, Linda   +2 more
core   +1 more source

Investigation of interactions between porcine endogenous retroviruses (PERV) and susceptible host cells

Die Xenotransplantation (XTx) vom Schwein auf den Menschen hat das Potenzial, den Mangel an menschlichen Allotransplantaten zu beheben. Trotz der erheblichen Fortschritte der letzten Jahre kann das zoonotische Risiko durch die potenzielle Übertragung porziner endogener Retroviren (PERVs) nicht ausgeschlossen werden. Im Gegensatz zu den meisten porzinen
openaire   +2 more sources

Viral pathogens: what are they and do they matter? [PDF]

, 2018
Andrea Perota, Cesare Galli, Claire Crossan, Cooper, Cooper, Crossan, Crossan, Denner, Denner, Denner, Denner, Denner, Denner, Fishman, Fishman, Gazda, Guell, Irwin, Linda Scobie, Morozov, Mourad, Nicuolo, Nizar I. Mourad, Onions, Paradis, Pierre Gianello, Scobie, Scobie, Spizzo, Wynyard, Yang   +30 more
core   +1 more source

Presence of Porcine Endogenous Retrovirus C in Domestic Pigs in Kansas [PDF]

There is currently a shortage of organs available to perform allotransplants in humans, prompting the exploration of xenotransplantation as an alternative.
Gillock, Eric T., Welton, Avery
core   +1 more source

No transmission of porcine endogenous retroviruses (PERVs) in a long-term pig to rat xenotransplantation model and no infection of immunosuppressed rats.

Annals of transplantation, 2008
Xenotransplantation from pig to humans may be associated with the risk of transmission of porcine endogenous retroviruses (PERVs) that are present in the genome of all pigs and that infect human cells in vitro. However, it remains unclear whether PERVs infect transplant recipients in vivo and, if so, whether they are pathogenic.
Joachim, Denner, Volker, Specke, Alexander, Karlas, Irina, Chodnevskaja, Thomas, Meyer, Vasiliy, Moskalenko, Reinhard, Kurth, Karin, Ulrichs   +7 more
openaire   +1 more source

Methods and Tools for Detection and Evaluation of the Risks of Porcine Endogenous Retrovirus in Porcine to Human Xenotransplantation [PDF]

, 2012
Carolyn A. Wilson, Takele Argaw
core   +1 more source

Progress of transgenic pigs in liver xenotransplantation. [PDF]

Liver Res
Xie XM, Wang GY.
europepmc   +1 more source

Further Evidence for the Immunosuppressive Activity of Transmembrane Envelope Protein p15E of Porcine Endogenous Retrovirus. [PDF]

Int J Mol Sci
Denner J, Schwinzer R, Pokoyski C, Kaufer BB, Dierkes B, Ban J, Lovlesh L.   +6 more
europepmc   +1 more source