Reliable Polymerase Chain Reaction Methods for Screening for Porcine Endogenous Retroviruses-C (PERV-C) in Pigs [PDF]
VirusesPorcine endogenous retrovirus C (PERV-C) is a gammaretrovirus present in the genome of many, but not all, pigs. It is an ecotropic virus, able to infect only pig cells.
Vasileios G Papatsiros +2 more
exaly +9 more sources
Determination of the Copy Number of Porcine Endogenous Retroviruses (PERV) in Auckland Island Pigs Repeatedly Used for Clinical Xenotransplantation and Elimination of PERV-C [PDF]
Microorganisms, 2023 Auckland Island pigs represent an inbred population of feral pigs isolated on the sub-Antarctic island for over 100 years. The animals have been maintained under pathogen-free conditions in New Zealand; they are well characterized virologically and have ...
Uwe Fiebig +2 more
doaj +8 more sources
Analysis of PERV-C superinfection resistance using HA-tagged viruses [PDF]
Retrovirology, 2023 Background Using pigs as organ donors has advanced xenotransplantation to the point that it is almost ready for clinical use. However, there is still a zoonotic risk associated with xenotransplantation, and the potential transmission of porcine ...
Merle Flecks +4 more
doaj +4 more sources
Monitoring for PERV Following Xenotransplantation [PDF]
Transplant InternationalPorcine endogenous retroviruses (PERVs) are integrated in the genome of all pigs. PERV-A, PERV-B and PERV-C can be released as infectious virus particles and PERV-A and PERV-B can infect human cells in culture.
Joachim Denner
doaj +5 more sources
Application of Methods Detecting Xenotransplantation-Relevant Viruses for Screening German Slaughterhouse Pigs [PDF]
VirusesDetection methods have been developed to prevent transmission of zoonotic or xenozoonotic porcine viruses after transplantation of pig organs or cells to the recipient (xenotransplantation).
Hina Jhelum +2 more
doaj +5 more sources
Correction: Analysis of PERV-C superinfection resistance using HA-tagged viruses [PDF]
RetrovirologyMerle Flecks +4 more
doaj +3 more sources
Viruses, 2021 Minipigs play an important role in biomedical research and they have also been used as donor animals for preclinical xenotransplantations. Since zoonotic microorganisms including viruses can be transmitted when pig cells, tissues or organs are ...
Joachim Denner
exaly +3 more sources
Virological and Parasitological Characterization of Mini-LEWE Minipigs Using Improved Screening Methods and an Overview of Data on Various Minipig Breeds [PDF]
Microorganisms, 2021 Minipigs play an important role in biomedical research and have also been used as donor animals in xenotransplantation. To serve as a donor in xenotransplantation, the animals must be free of potential zoonotic viruses, bacteria and parasites.
Sabrina Halecker +5 more
doaj +6 more sources
Characterization of porcine endogenous retrovirus insertion in Jeju native pigs and commercial breeds [PDF]
Animal BioscienceObjective This study aimed to characterize the genomic distribution and amino acid homology of porcine endogenous retrovirus (PERV) subtypes in three pig breeds, Jeju native pigs (JNPs), Duroc, and Landrace.
Seungwon Yoon +9 more
doaj +2 more sources
Neutralizing Antibodies Against the Porcine Endogenous Retroviruses (PERVs) [PDF]
VirusesXenotransplantation using pig cells, tissues or organs may be associated with the transmission of porcine zoonotic or xenozoonotic microorganisms. Porcine endogenous retroviruses (PERVs) pose a special risk for xenotransplantation as these viruses can ...
Jinzhao Ban +3 more
doaj +2 more sources