Results 21 to 30 of about 3,898 (163)
Deleting PERV C infectious potential from donor pigs for xenotransplantation [PDF]
, 2019 Kola, Ingrid
openaire +3 more sources
Characterization of Insertional Variation of Porcine Endogenous Retroviruses in Six Different Pig Breeds [PDF]
Asian-Australasian Journal of Animal Sciences, 2012 Pigs may need to be exploited as xenotransplantation donors due to the shortage of human organs, tissues and cells. Porcine endogenous retroviruses (PERVs) are a significant obstacle to xenotransplantation because they can infect human cells in vitro and
W. Y. Jung +7 more
doaj +1 more source
Scientific Reports, 2020 Several xenogenic cell-based therapeutic products are currently under development around the world for the treatment of human diseases. Porcine islet cell products for treating human diabetes are a typical example.
Ken Kono +5 more
doaj +1 more source
Біологія тварин, 2021 The article presents the analysis of the PERV retrovirus subtypes A and C frequency in populations of Ukrainian and foreign breed pigs. Different frequencies of the PERV A/C genome presence in animals of the studied breeds were established.
T. M. Ryk
doaj +1 more source
First virological and pathological study of Göttingen Minipigs with Dippity Pig Syndrome (DPS).
PLoS ONE, 2023 Dippity Pig Syndrome (DPS) is a well-known but rare complex of clinical signs affecting minipigs, which has not been thoroughly investigated yet. Clinically affected animals show acute appearance of red, exudating lesions across the spine.
Hina Jhelum +13 more
doaj +1 more source
Suboptimal porcine endogenous retrovirus infection in non-human primate cells: implication for preclinical xenotransplantation. [PDF]
PLoS ONE, 2010 BACKGROUND: Porcine endogenous retrovirus (PERV) poses a potential risk of zoonotic infection in xenotransplantation. Preclinical transplantation trials using non-human primates (NHP) as recipients of porcine xenografts present the opportunity to assess ...
Giada Mattiuzzo, Yasuhiro Takeuchi
doaj +1 more source
Microlocal sheaves and quiver varieties [PDF]
, 2015 We relate Nakajima Quiver Varieties (or, rather, their multiplicative version) with moduli spaces of perverse sheaves. More precisely, we consider a generalization of the concept of perverse sheaves: microlocal sheaves on a nodal curve X.
Bezrukavnikov, Roman, Kapranov, Mikhail
core +3 more sources
Cytotoxic Effects during Knock Out of Multiple Porcine Endogenous Retrovirus (PERV) Sequences in the Pig Genome by Zinc Finger Nucleases (ZFN) [PDF]
, 2015 Xenotransplantation has been proposed as a solution to the shortage of suitable human donors for transplantation and pigs are currently favoured as donor animals.
Denner, Joachim +2 more
core +8 more sources
Frontiers in Microbiology, 2022 Domestic pigs has served not only as one of the most important economy livestock but also as ideal organ-source animals owing to similarity in anatomy, physiology, and organ size to humans.
Tao-feng Lu +5 more
doaj +1 more source
Porcine Endogenous Retrovirus Induces CXCL10 in Human Monocytes and Monocyte-Derived Primary Cells
Intervirology, 2022 Introduction: Pigs are suitable donor species for xenotransplantation and biological materials from these animals are used for this purpose for many years.
Hussein Al-Shehabi, Norbert Bannert
doaj +1 more source