Results 41 to 50 of about 18,673,205 (171)
Pig is the most promising species for transplantation of organs and cells into humans, although implementation of xenotransplantation in clinical practice has been hindered by the risk of infecting the recipient with zoonotic infectious diseases. Porcine
R. B. Aitnazarov +4 more
doaj +1 more source
Knockdown of porcine endogenous retrovirus (PERV) expression by PERV-specific shRNA in transgenic pigs [PDF]
Background: Xenotransplantation using porcine cells, tissues or organs may be associated with the transmission of porcine endogenous retroviruses (PERVs).
Dieckhoff, Britta +9 more
core +1 more source
Hardware‐learning co‐design combines volar‐plate‐inspired passive‐joint constraints with mechanism‐aware reinforcement learning for a low‐cost parallel‐linkage gripper. The resulting system performs quasi‐static object adjustment and dynamic pinch grasping, demonstrating reliable planar in‐hand manipulation and successful sim‐to‐real transfer. Parallel
Yanzhou Jin +4 more
wiley +1 more source
Characterisation of a human cell-adapted porcine endogenous retrovirus PERV-A/C. [PDF]
Background: Porcine endogenous retroviruses (PERVs) pose a potential risk for xenotransplantation using pig cells, tissues or organs. A special threat comes from viruses generated by recombination between human-tropic PERV-A and ecotropic PERV-C ...
Specke, Volker +6 more
core +1 more source
Engineering Biology Beyond Single Genes: Advances and Challenges in Multiplex Genome Editing
Multiplex genome editing is transforming genome engineering from single‐gene perturbation to network‐level control, yet its broader application remains limited by challenges in gRNA array engineering, delivery technologies, and safety management. Emerging AI‐driven approaches are accelerating guide RNA design and CRISPR effector optimization for ...
Linli Wang, Yongbin Liu, Hongbing Han
wiley +1 more source
ABSTRACT Sustainability‐related human rights risks, including forced labour, labour exploitation and other forms of human rights abuse, remain persistent challenges across countries, particularly where corporate accountability and national institutional frameworks are weak.
Doaa Shohaieb +3 more
wiley +1 more source
The article presents the results of the analysis of the frequency of PERV retroviruses of subtypes A and C in populations of pigs of Ukrainian and foreign breeds.
Tetiana Mikolaivna Ryk
doaj
Xenotransplantation: Reduction of the risk of transmission of porcine endogenous retroviruses (PERV) [PDF]
Xenotransplantation using porcine cells, tissues or organs may reduce the widening gap between demand and supply of human donor organs. However, this may be hampered by the presence of porcine endogenous retroviruses (PERVs), which belong to the γ ...
Semaan, Marwan
core +1 more source
ABSTRACT Background Transcatheter aortic valve implantation (TAVI) with the Acurate Neo has been linked to a significant incidence of paravalvular leakage (PVL), addressed by the Acurate Neo 2 incorporating an active sealing skirt. Recent findings suggest that midframe under‐expansion is associated with worse outcomes.
Lisa Crusius +9 more
wiley +1 more source
Transplantation of pig tissues into humans has the potential for cotransferring pig infections. Knowledge of the epidemiology of pig infections transmissible to humans allows the development of risk limitation strategies at the source herd level, but ...
R. B. Elliott +8 more
doaj +1 more source

