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Transboundary and Emerging Diseases, 2011 Previous studies have linked levels of porcine endogenous retroviruses (PERV)with poor health and disease in pigs. To determine the levels of expression ofPERVs and their potential association with disease expression, real-time reversetranscriptase (RT ...
Pal, N. +11 more
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Recombinant porcine endogenous retroviruses (PERV-A/C): a new risk for xenotransplantation?
Archives of Virology, 2008The zoonotic transmissions from non‐human primates of the human immunodeficiency virus (HIV‐1) that initiated the AIDS pandemic and the spread of many emerging infectious diseases teaches us that there is a need for carefully consider the potential risks associated with xenotransplantation. Whereas known viruses can easily be eliminated from donor pigs
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Xenotransplantation, 2001
Abstract: Xenotransplantation may be associated with the risk of transmission of microorganisms. In particular, the porcine endogenous retroviruses (PERV) have raised concerns as in vitro experiments show susceptibility of human cells for PERV infection.
Joachim Denner, K Boller
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Abstract: Xenotransplantation may be associated with the risk of transmission of microorganisms. In particular, the porcine endogenous retroviruses (PERV) have raised concerns as in vitro experiments show susceptibility of human cells for PERV infection.
Joachim Denner, K Boller
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Virus Research, 2004
PCR amplification of proviral DNA extracted from peripheral blood lymphocytes of three Chinese pigs (Banna minipig inbreed (BMI), Wu-Zhi-Shan pig (WZSP) and Neijiang pig (NJP)), using primers corresponding to highly conserved regions of reverse transcriptase (RT) of pol gene and nucleocapsid sequence of gag gene.
Zhang, Li +6 more
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PCR amplification of proviral DNA extracted from peripheral blood lymphocytes of three Chinese pigs (Banna minipig inbreed (BMI), Wu-Zhi-Shan pig (WZSP) and Neijiang pig (NJP)), using primers corresponding to highly conserved regions of reverse transcriptase (RT) of pol gene and nucleocapsid sequence of gag gene.
Zhang, Li +6 more
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Archives of Virology, 2002
Porcine endogenous retroviruses (PERVs) are considered a special risk for xenotransplantation because they are an integral part of the porcine genome and are able to infect cells of numerous species including humans in vitro. Among these cells, the mink lung epithelial cell line Mv1Lu could be productively infected with PERV.
V, Specke +4 more
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Porcine endogenous retroviruses (PERVs) are considered a special risk for xenotransplantation because they are an integral part of the porcine genome and are able to infect cells of numerous species including humans in vitro. Among these cells, the mink lung epithelial cell line Mv1Lu could be productively infected with PERV.
V, Specke +4 more
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DTW. Deutsche tierarztliche Wochenschrift, 1999
The pig is the favorized donor species for clinical xenotransplantation. However, PATIENCE et al. could show, that porcine endogenous retroviruses (PERV), released by a porcine kidney cell line, are capable of infecting human cell lines in vitro. Based on this discovery there is an ongoing discussion concerning the risks of zoonosis combined with ...
U, Martin, G, Steinhoff
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The pig is the favorized donor species for clinical xenotransplantation. However, PATIENCE et al. could show, that porcine endogenous retroviruses (PERV), released by a porcine kidney cell line, are capable of infecting human cell lines in vitro. Based on this discovery there is an ongoing discussion concerning the risks of zoonosis combined with ...
U, Martin, G, Steinhoff
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Blood, 2005
Abstract Susceptibility of human hematopoietic stem cells to infection with porcine endogenous retroviruses (PERV) is of prime importance in determining the feasibility and safety of transplanting pig organs into humans. Under the influence of lineage specific cytokines, umbilical cord blood stem cells were evaluated for their ...
Carolyn A. Wilson +2 more
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Abstract Susceptibility of human hematopoietic stem cells to infection with porcine endogenous retroviruses (PERV) is of prime importance in determining the feasibility and safety of transplanting pig organs into humans. Under the influence of lineage specific cytokines, umbilical cord blood stem cells were evaluated for their ...
Carolyn A. Wilson +2 more
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Characterising and Mapping Porcine Endogenous Retroviruses (PERVs)
2000The initial focus of this PhD project was on comparative gene mapping. Comparative gene mapping is facilitated by consensus PCR primers which amplify homologous gene fragments in many species. As a part of an international co-ordinated programme of comparative mapping in pigs, 47 CATS (Comparative Anchor Tagged Sequence) consensus primer pairs for loci
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Porcine endogenous retroviruses (PERVs) and xenotransplantation
DMW - Deutsche Medizinische Wochenschrift, 2003openaire +1 more source
Absence of porcine endogenous retrovirus (PERV) production from pig lymphoma cell lines
Virus Research, 2021Christene A Huang +2 more
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