Results 51 to 60 of about 882 (164)
Safety of Xenotransplantation: Development of screening methods and testing for porcine viruses [PDF]
, 2018 Xenotransplantation using pig cells, tissues or organs might be a promising solution to overcome the shortage for organs suitable for allotransplantation. Because of several reasons, the pig is currently the favoured donor species.
Janich geb. Plotzki, Elena
core +1 more source
Viruses, 2017 Porcine endogenous retroviruses (PERVs) are integrated in the genome of all pigs; they are released as infectious particles, and under certain conditions they can infect human cells. Therefore, they represent a risk when pigs are used as sources of cells,
Joachim Denner
doaj +1 more source
The role of genetically engineered pigs in xenotransplantation research [PDF]
, 2015 There is a critical shortage in the number of deceased human organs that become available for the purposes of clinical transplantation. This problem might be resolved by the transplantation of organs from pigs genetically engineered to protect them from ...
Ayares, David +4 more
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Xenotransplantation: Perspectives and limits [PDF]
, 2001 Xenotransplantation faces the dilemma of an unlimited supply of cells, tissues and organs on the one hand and severe obstacles and limits on the other. One reason for the limitations is that the source animal of choice, the pig, and the human recipient ...
Hammer, Claus
core +1 more source
Xenotransplantation: past, present, and future [PDF]
, 2017 PURPOSE OF REVIEW: To review the progress in the field of xenotransplantation with special attention to most recent encouraging findings which will eventually bring xenotransplantation to the clinic in the near future.
Cooper, David K.C. +2 more
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Porcine to Human Heart Transplantation: Is Clinical Application Now Appropriate? [PDF]
, 2017 Cardiac xenotransplantation (CXTx) is a promising solution to the chronic shortage of donor hearts. Recent advancements in immune suppression have greatly improved the survival of heterotopic CXTx, now extended beyond 2 years, and life-supporting kidney ...
Byrne, GW, McGregor, CGA
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Viruses, 2016 Transspecies transmission of retroviruses is a frequent event, and the human immunodeficiency virus-1 (HIV-1) is a well-known example. The gibbon ape leukaemia virus (GaLV) and koala retrovirus (KoRV), two gammaretroviruses, are also the result of a ...
Joachim Denner
doaj +1 more source
The ethics of xenotransplantation [PDF]
, 2000 Xenotransplantation - moving organs from one species to another - is currently being actively researched as a possible contribution to the problem of a global shortage of human organs for transplants.
Reiss, Michael
core +3 more sources
Presence of Porcine Endogenous Retrovirus C in Domestic Pigs [PDF]
, 2023 The goal of this study is to create new mutations in the Asymmetric Leaves1 (AS1) gene of Arabidopsis using CRISPR vectors to induce mutations. The intention is to analyze these mutations in order to better understand the structure and function of the ...
Welton, Avery
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Journal of Animal Science and Biotechnology, 2022 Background A comprehensive landscape of chromatin states for multiple mammalian tissues is essential for elucidating the molecular mechanism underlying regulatory variants on complex traits.
Tao Jiang +10 more
doaj +1 more source