Results 91 to 100 of about 181,641 (132)

In vitro and in vivo evaluation of thapsigargin as an antiviral agent against transmissible gastroenteritis virus

Veterinary Research
Swine enteric coronaviruses (SeCoVs) pose a significant threat to the global pig industry, but no effective drugs are available for treatment. Previous research has demonstrated that thapsigargin (TG), an ER stress inducer, has broad-spectrum antiviral ...
Yang Li, Yuanyuan Liu, Yunhang Zhang, Chen Tan, Yifei Cai, Yue Zhang, Jianing Chen, Yuguang Fu, Guangliang Liu   +8 more
doaj   +1 more source

Drug repurposing screens identify Tubercidin as a potent antiviral agent against porcine nidovirus infections

Virus Research
The emergence of new coronaviruses poses a significant threat to animal husbandry and human health. Porcine epidemic diarrhea virus (PEDV) is considered a re-emerging porcine enteric coronavirus, which causes fatal watery diarrhea in piglets.
Tianliang Wang, Guanmin Zheng, Zilu Chen, Yue Wang, Chenxu Zhao, Yaqin Li, Yixin Yuan, Hong Duan, Hongsen Zhu, Xia Yang, Wentao Li, Wenjuan Du, Yongtao Li, Dongliang Li   +13 more
doaj   +1 more source

Publication Only

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

ALIX and TSG101 are essential for cellular entry and replication of two porcine alphacoronaviruses.

PLoS Pathogens
Alphacoronaviruses are the primary coronaviruses responsible for causing severe economic losses in the pig industry with the potential to cause human outbreaks.
Xiongnan Chen, Yifan Liang, Zhijun Weng, Chen Hu, Yunzhao Peng, Yingshuo Sun, Qi Gao, Zhao Huang, Shengqiu Tang, Lang Gong, Guihong Zhang   +10 more
doaj   +1 more source

Enteral coronaviruses of swine - Literature review [PDF]

, 2018
SUMMARY Enteric diseases induced by viruses are highly prevalent and have great economic importance in the swine industry. From the many viruses, which can be found in the background of watery diarrhoea the coronaviruses were chosen to be ...
Tuboly, Tamás, Valkó, Anna, Cságola, Attila   +2 more
core  

A novel double-antibody sandwich ELISA based on monoclonal antibodies against the viral spike protein detects porcine deltacoronavirus infection

Microbiology Spectrum
Porcine deltacoronavirus (PDCoV) is a significant emerging pathogen that causes severe enteric disease in swine, and therefore significant economic losses in the pig farming industry.
Yingjie Bai, Ruiming Yu, Guangqing Zhou, Liping Zhang, TianTian Wang, Ya Liu, Dongsheng Wang, Zhongwang Zhang, Yonglu Wang, Huichen Guo, Li Pan, Xinsheng Liu   +11 more
doaj   +1 more source

Coronavirosis: analysis of the main coronaviruses of veterinary and human interest in a one health perspective

, 2021
The family Coronaviridae includes it the subfamily Coronavdisease of cattirinae which is divided in four different genera: Alphacoronavirus, Betacoronavirus, Gammacoronavirus and Deltacoronavirus. Belonging to the same family, they have some very similar
Mezzasalma, Nicolò
core  

Porcine gastroenteric viruses: pathogenesis and protection

, 2020
The complexity of known porcine coronaviruses (CoVs) has considerably increased. To the classical transmissible gastroenteritis virus (TGEV) known since 1946, its deletion mutant with an exclusive respiratory tropism, the porcine respiratory CoV (PRCV),
Pascual-Iglesias, Alejandro, Enjuanes Sánchez, Luis, Zúñiga Lucas, Sonia, Sánchez, Carlos M., Carlos Zaberezhny, A. D.   +4 more
core  

Emerg Infect Dis

Porcine epidemic diarrhea virus (PEDV) has been detected sporadically in Europe since the 1990s. We report the phylogenetic relationship of swine enteric coronaviruses collected in Europe during 2007-2014 and identify a drastic shift in PEDV strain ...

core  

CRISPR-based screening of host factors in veterinary viral infections: from target discovery to host-directed antiviral strategies. [PDF]

Front Vet Sci
Liu Y, Xu L, Yin Y.
europepmc   +1 more source