Results 71 to 80 of about 181,641 (132)

Programmable DNA‐Peptide Hybrid Nanostructures for Potent Neutralization of Multiple Influenza a Virus Subtypes

Advanced Functional Materials, Volume 36, Issue 31, 16 April 2026.
A multivalent antiviral platform based on honeycomb‐shaped DNA nanostructures (HC–Urumin) is developed to enhance the potency and breadth of the host defense peptide Urumin. Through spatially patterned trimeric presentation, HC–Urumin disrupts influenza A virus entry, improves cell viability, and reduces disease severity in vivo‐offering a modular and ...
Saurabh Umrao, Abhisek Dwivedy, Payton L. Haak, Dhanush Gandavadi, Laurie A. Rund, Chi Chen, Vineetha Mareddy, Lifeng Zhou, Jinwei Duan, Ying Fang, Andrew J. Steelman, Xing Wang   +11 more
wiley   +1 more source

Porcine coronaviruses: transmission, pathogenesis and vaccine development

, 2020
Trabajo presentado en el VII International Veterinary Congress, celebrado en Ufa (Rusia), del 19 al 21 de abril de 2017Porcine enteric coronaviruses (CoVs) cause severe disease in the porcine herds worldwide, leading to important economic losses.
Pascual-Iglesias, Alejandro, Solá Gurpegui, Isabel, Enjuanes Sánchez, Luis, Zúñiga Lucas, Sonia, Sánchez, Carlos M., Zaberezhny, A   +5 more
core  

Coronavirus Nsp3 Hijacks CLTC to Modulate Autophagosome Nucleation for Promoting DMV Formation and Viral Replication

Advanced Science, Volume 13, Issue 24, 27 April 2026.
In wild‐type cells, FIPV infection recruits CLTC to nsp3, facilitates DMV biogenesis and block autophagic flux to promote viral replication. CLTC knockout impairs autophagosome nucleation by reducing Beclin1–ATG14 complex expression. This disrupts the formation of autophagic precursor membranes, thereby preventing their hijacking by nsp3 for DMV ...
Juan Xu, Hang Li, Peng Liu, Zhe Jiao, Ding Zhang, Zhelin Su, Sai Niu, Jintao Zhang, Yuejun Shi, Guiqing Peng   +9 more
wiley   +1 more source

Retrospective Serosurvey of Three Porcine Coronaviruses among the Wild Boar (Sus scrofa) Population in the Campania Region of Italy

, 2022
The growing interest in porcine coronaviruses (CoVs) is due to both their negative effect on the swine industry and their propensity to mutate and overcome host barriers. Since information on CoVs in wild boar (Sus scrofa) is limited, especially in Italy,
Ferrara, Gianmarco, Longobardi, Consiglia, Fioretti, Alessandro, Damiano, Sara, Nocera, Francesca Paola, Montagnaro, Serena, Iovane, Giuseppe, Pagnini, Ugo, Ciarcia, Roberto, Ferrara G., Montagnaro S., Nocera F. P., Longobardi C., Fioretti A., Damiano S., Iovane G., Ciarcia R., Pagnini U.   +17 more
core   +1 more source

Therapeutic Gases in Biomedicine: Updates on Nitric Oxide and Beyond

Advanced Science, Volume 13, Issue 23, 23 April 2026.
Therapeutic gases, including NO, CO, H2S, H2, CO2, O2, and Xe, play vital roles in cellular signaling and repair. This review highlights the emerging carriers and delivery systems that enable controlled, localized gas release for diagnostic and therapeutic applications.
Syed Muntazir Andrabi, Navatha Shree Sharma, Imran Ibn Gani Rather, S. M. Shatil Shahriar, Jingwei Xie   +4 more
wiley   +1 more source

Trivalent mRNA-LNP Vaccine Induces Robust Humoral and Cellular Immunity in Mice: Preclinical Evaluation for Porcine Enteric Coronaviruses

International Journal of Nanomedicine
Porcine enteric coronaviruses (PECs) often co-infect swine, leading to high mortality, which underscores the need for multivalent vaccines.A trivalent mRNA vaccine was formulated using SM-102 lipid nanoparticles (LNPs) and encodes PEDV-SCOE, PDCoV-SCTD, and TGEV-SAD in a single transcript.
Xinfei Wang, Chen Li, Shuo Wang, Chang Liu, Jianli Shi, Wenxin Xu, Shun Zhou, Shaojian Xu, Yingli Shang, Jun Li   +9 more
openaire   +3 more sources

Origin, Evolution, and Virulence of Porcine Deltacoronaviruses in the United States

mBio, 2015
A novel porcine deltacoronavirus (PdCV) was first discovered in Ohio and Indiana in February 2014, rapidly spread to other states in the United States and Canada, and caused significant economic loss in the swine industry.
Yuanmei Ma, Yu Zhang, Xueya Liang, Fangfei Lou, Michael Oglesbee, Steven Krakowka, Jianrong Li   +6 more
doaj   +1 more source

Rapid Selective Detection of Potentially Infectious Porcine Epidemic Diarrhea Coronavirus Exposed to Heat Treatments Using Viability RT-qPCR

Frontiers in Microbiology, 2020
Coronaviruses (CoVs) cause severe respiratory, enteric, and systemic infections in a wide range of hosts, including humans and animals. Porcine epidemic diarrhea virus (PEDV), a member of the Coronaviridae family, is the etiological agent of porcine ...
Héctor Puente, Walter Randazzo, Irene Falcó, Ana Carvajal, Gloria Sánchez   +4 more
doaj   +1 more source

Nano‐ and Micro‐Sized Solid Materials Used as Antiviral Agents

Advanced Functional Materials, Volume 36, Issue 26, 30 March 2026.
Due to the rise of viral infections in humans and possible viral outbreaks, the use of nano‐ or micro‐sized materials as antiviral agents is rapidly increasing. This review explores their antiviral properties against RNA and DNA viruses, either as a prevention or a treatment tool, by delving into their mechanisms of action and how to properly assess ...
Orfeas‐Evangelos Plastiras, Imelda Raczkiewicz, Peggy Bouquet, Jean‐Philippe Dacquin, Jeremy Dhainaut, Anne Goffard, Christophe Volkringer   +6 more
wiley   +1 more source

A Serological Investigation of Porcine Reproductive and Respiratory Syndrome and Three Coronaviruses in the Campania Region, Southern Italy

, 2023
Porcine coronaviruses and reproductive and respiratory syndrome (PRRS) are responsible for severe outbreaks that cause huge economic losses worldwide. In Italy, three coronaviruses have been reported historically: porcine epidemic diarrhea virus (PEDV ...
Ferrara, Gianmarco, Serena Montagnaro, Elvira Improda, D'Anza, Emanuele, Montagnaro, Serena, Emanuele D’Anza, Ugo Pagnini, Pagnini, Ugo, Rossi, Antonella, Valentina Iovane, Giuseppe Iovane, Iovane, Giuseppe, Improda, Elvira, Antonella Rossi, Gianmarco Ferrara, Iovane, Valentina, Improda, Envira, D’Anza, Emanuele   +17 more
core   +1 more source