Results 51 to 60 of about 181,641 (132)

In situ hybridization technique for the detection of swine enteric and respiratory coronaviruses, transmissible gastroenteritis virus (TGEV) and porcine respiratory coronavirus (PRCV), in formalin-fixed paraffin-embedded tissues

open access: yesJournal of Virological Methods, 1996
The in situ hybridization (ISH) technique was developed to detect the swine coronaviruses, transmissible gastroenteritis virus (TGEV) and porcine respiratory coronavirus (PRCV), in cell culture and tissue sections from TGEV-or PRCV-infected pigs. The 35S-labeled RNA probes were generated from two plasmids pPSP.FP1 and pPSP.FP2 containing part of the S ...
Sirinarumitr, Theerapol   +3 more
openaire   +2 more sources

Porcine Intestinal Organoids for the Study of Host-Pathogen Porcine Enteric Viruses

open access: yes, 2023
International audienceThe study of host-virus interactions is essentially performed in cell culture and animal models. These approaches come up against a double problem i) methodological, linked most of the time to the use of immortalized cell lines ...
Duchesne, Camille   +7 more
core  

Table_4_Long-Term Expansion of Porcine Intestinal Organoids Serves as an in vitro Model for Swine Enteric Coronavirus Infection.XLSX

open access: yes, 2022
A reliable and reproducible model in vitro for swine enteric coronaviruses infection would be intestinal models that support virus replication and can be long-term cultured and manipulated experimentally.
Fei Gao (29262)   +11 more
core   +1 more source

Porcine Deltacoronavirus M Protein Binds NLRP3 to Promote Inflammasome Assembly via Competition with TRIM31

open access: yesAdvanced Science, Volume 13, Issue 54, 28 September 2026.
Porcine deltacoronavirus (PDCoV) infection induces severe intestinal inflammation and acute diarrhea in piglets, yet the molecular mechanism remains incompletely understood. The M protein activates NLRP3 inflammasome through dual mechanisms: direct binding to the NLRP3 LRR domain and disruption of TRIM31‐mediated K48‐linked ubiquitination.
Jinhui Hou   +11 more
wiley   +1 more source

A Novel Pathogenic Mammalian Orthoreovirus from Diarrheic Pigs and Swine Blood Meal in the United States

open access: yesmBio, 2015
Since May 2013, outbreaks of porcine epidemic diarrhea have devastated the U.S. swine industry, causing immense economic losses. Two different swine enteric coronaviruses (porcine epidemic diarrhea virus and Delta coronavirus) have been isolated from the
Athmaram Thimmasandra Narayanappa   +13 more
doaj   +1 more source

Characterization and immunogenicity of nanoparticle vaccines displaying embecovirus spike proteins

open access: yesBiotechnology Progress, Volume 42, Issue 5, September/October 2026.
Virus‐like particle vaccines displaying spike proteins from OC43, HKU1 A, and HKU1 B were evaluated in mice for their ability to elicit antibodies against the spike proteins from OC43, HKU1 A, HKU1 B, and HKU1 C. Abstract Endemic human coronaviruses OC43 and HKU1 cause widespread respiratory infections and can be associated with severe illness in ...
Peter J. Halfmann   +6 more
wiley   +1 more source

Table_5_Long-Term Expansion of Porcine Intestinal Organoids Serves as an in vitro Model for Swine Enteric Coronavirus Infection.XLSX

open access: yes, 2022
A reliable and reproducible model in vitro for swine enteric coronaviruses infection would be intestinal models that support virus replication and can be long-term cultured and manipulated experimentally.
Fei Gao (29262)   +11 more
core   +1 more source

A Review of Veterinary and Economically Devastating Coronaviruses: Emphasising Poultry and Pigs [PDF]

open access: yes, 2023
Coronaviruses are known can cause a significant impact on veterinary medicine and socio-economic. Understanding the biological characteristics and dynamics of pathogenic coronaviruses is a major scientific challenge with potential impacts on animal ...
Mohd Iswadi ISMAIL
core   +1 more source

Development and application of an ELISA for the detection of porcine deltacoronavirus IgG antibodies. [PDF]

open access: yesPLoS ONE, 2015
Porcine deltacoronavirus (PDCoV), also known as porcine coronavirus HKU15, was first detected in North America in early 2014 and associated with enteric disease in pigs, resulting in an urgent need to further investigate the ecology of this virus.
Anil Thachil   +4 more
doaj   +1 more source

Broad antagonism of coronaviruses nsp5 to evade the host antiviral responses by cleaving POLDIP3.

open access: yesPLoS Pathogens, 2023
Coronaviruses (CoVs) are a family of the largest RNA viruses that typically cause respiratory, enteric, and hepatic diseases in animals and humans, imposing great threats to the public safety and animal health.
Yang Wu   +9 more
doaj   +1 more source

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