Results 11 to 20 of about 4,534 (155)

PEDV and PDCoV Pathogenesis: The Interplay Between Host Innate Immune Responses and Porcine Enteric Coronaviruses [PDF]

Frontiers in Veterinary Science, 2019
Enteropathogenic porcine epidemic diarrhea virus (PEDV) and porcine deltacoronavirus (PDCoV), members of the coronavirus family, account for the majority of lethal watery diarrhea in neonatal pigs in the past decade.
Surapong Koonpaew, Samaporn Teeravechyan, Phanramphoei Namprachan Frantz, Thanathom Chailangkarn, Anan Jongkaewwattana   +4 more
doaj   +5 more sources

Monitoring emerging pathogens using negative nucleic acid test results from endemic pathogens in pig populations: Application to porcine enteric coronaviruses. [PDF]

PLoS ONE
This study evaluated the use of endemic enteric coronaviruses polymerase chain reaction (PCR)-negative testing results as an alternative approach to detect the emergence of animal health threats with similar clinical diseases presentation.
Ana Paula Serafini Poeta Silva, Guilherme Arruda Cezar, Edison Sousa Magalhães, Kinath Rupasinghe, Srijita Chandra, Gustavo S Silva, Marcelo Almeida, Bret Crim, Eric Burrough, Phillip Gauger, Christopher Siepker, Marta Mainenti, Michael Zeller, Rodger G Main, Mary Thurn, Paulo Fioravante, Cesar Corzo, Albert Rovira, Hemant Naikare, Rob McGaughey, Franco Matias Ferreyra, Jamie Retallick, Jordan Gebhardt, Angela Pillatzki, Jon Greseth, Darren Kersey, Travis Clement, Jane Christopher-Hennings, Melanie Prarat, Ashley Johnson, Dennis Summers, Craig Bowen, Kenitra Hendrix, Joseph Boyle, Daniel Correia Lima Linhares, Giovani Trevisan   +35 more
doaj   +5 more sources

Swine Enteric Coronaviruses (PEDV, TGEV, and PDCoV) Induce Divergent Interferon-Stimulated Gene Responses and Antigen Presentation in Porcine Intestinal Enteroids [PDF]

Frontiers in Immunology, 2022
Swine enteric coronaviruses (SECoVs) including porcine epidemic diarrhea virus (PEDV), transmissible gastroenteritis virus (TGEV), and porcine deltacoronavirus (PDCoV), account for the majority of lethal watery diarrhea in neonatal pigs and pose ...
Lingdan Yin, Xiang Liu, Dongmei Hu, Yi Luo, Guozhong Zhang, Pinghuang Liu   +5 more
doaj   +5 more sources

Porcine enteric coronaviruses: an updated overview of the pathogenesis, prevalence, and diagnosis. [PDF]

Vet Res Commun, 2021
The recent prevalence of coronavirus (CoV) poses a serious threat to animal and human health. Currently, porcine enteric coronaviruses (PECs), including the transmissible gastroenteritis virus (TGEV), the novel emerging swine acute diarrhoea syndrome coronavirus (SADS-CoV), porcine delta coronavirus (PDCoV), and re-emerging porcine epidemic diarrhoea ...
Liu Q, Wang HY.
europepmc   +6 more sources

Agrodiag PorCoV: A multiplex immunoassay for the differential diagnosis of porcine enteric coronaviruses. [PDF]

J Immunol Methods, 2020
Three different porcine enteric coronaviruses (PECs), i.e., porcine epidemic diarrhea virus (PEDV), transmissible gastroenteritis virus (TGEV) and porcine Deltacoronavirus (PDCoV) are currently circulating in U.S. commercial swine herds. Differential diagnosis of PECs relies on laboratory methods.
Malbec R, Kimpston-Burkgren K, Vandenkoornhuyse E, Olivier C, Souplet V, Audebert C, Carrillo-Ávila JA, Baum D, Giménez-Lirola L.   +8 more
europepmc   +7 more sources

A TaqMan-probe-based multiplex real-time RT-qPCR for simultaneous detection of porcine enteric coronaviruses. [PDF]

Appl Microbiol Biotechnol, 2019
Swine enteric coronaviruses are a group of most significant pathogens causing diarrhea in piglets with similar clinical symptoms and pathological changes. To develop a simple, rapid, accurate, and high-throughput detection method for diagnosis and differential diagnosis on swine enteric coronaviruses, specific primers and probes were designed based on ...
Huang X, Chen J, Yao G, Guo Q, Wang J, Liu G.   +5 more
europepmc   +6 more sources

Immune evasion of porcine enteric coronaviruses and viral modulation of antiviral innate signaling. [PDF]

Virus Res, 2016
Porcine epidemic diarrhea virus (PEDV) and porcine deltacoronavirus (PDCoV) are emerged and reemerging viruses in pigs, and together with transmissible gastroenteritis virus (TGEV), pose significant economic concerns to the swine industry. These viruses infect epithelial cells of the small intestine and cause watery diarrhea, dehydration, and a high ...
Zhang Q, Yoo D.
europepmc   +5 more sources

Modulation of Innate Antiviral Immune Response by Porcine Enteric Coronavirus

Frontiers in Microbiology, 2022
Host’s innate immunity is the front-line defense against viral infections, but some viruses have evolved multiple strategies for evasion of antiviral innate immunity.
Kunli Zhang, Kunli Zhang, Sen Lin, Jianhao Li, Shoulong Deng, Jianfeng Zhang, Jianfeng Zhang, Sutian Wang   +7 more
doaj   +3 more sources

IL-22 suppresses the infection of porcine enteric coronaviruses and rotavirus by activating STAT3 signal pathway. [PDF]

Antiviral Res, 2017
Interleukin-22 (IL-22), a member of the IL-10 superfamily, plays essential roles in fighting against mucosal microbial infection and maintaining mucosal barrier integrity within the intestine. However, little knowledge exists on the ability of porcine IL-22 (pIL-22) to fight against viral infection in the gut.
Xue M, Zhao J, Ying L, Fu F, Li L, Ma Y, Shi H, Zhang J, Feng L, Liu P.   +9 more
europepmc   +5 more sources

Long-Term Expansion of Porcine Intestinal Organoids Serves as an in vitro Model for Swine Enteric Coronavirus Infection

Frontiers in Microbiology, 2022
A reliable and reproducible model in vitro for swine enteric coronaviruses infection would be intestinal models that support virus replication and can be long-term cultured and manipulated experimentally.
Min Zhang, Min Zhang, Lilei Lv, Hongming Cai, Hongming Cai, Yanhua Li, Fei Gao, Fei Gao, Lingxue Yu, Lingxue Yu, Yifeng Jiang, Yifeng Jiang, Wu Tong, Wu Tong, Liwei Li, Liwei Li, Guoxin Li, Guoxin Li, Guangzhi Tong, Guangzhi Tong, Guangzhi Tong, Changlong Liu, Changlong Liu   +22 more
doaj   +3 more sources