CHARACTERISTICS AND OCCURRENCE OF CORONAVIRUSES IN HUMANS AND ANIMALS [PDF]
Health Problems of Civilization, 2020 Coronaviruses occurring in humans and animals are a diverse group of pathogens, characterized by high variability and tropism. The most serious animal diseases caused by coronaviruses include equine coronavirus disease (E-CoV), canine coronavirus disease
Marcin Weiner, Karolina Tarasiuk
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Coinfection and nonrandom recombination drive the evolution of swine enteric coronaviruses
Emerging Microbes and InfectionsCoinfection with multiple viruses is a common phenomenon in clinical settings and is a crucial driver of viral evolution. Although numerous studies have demonstrated viral recombination arising from coinfections of different strains of a specific species,
Jiahui Guo +8 more
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A trivalent inactivated PDCoV-PEDV-TGEV vaccine confers protective efficacy in piglets coinfected with porcine rotavirus [PDF]
Frontiers in Veterinary SciencePorcine epidemic diarrhea virus (PEDV), porcine deltacoronavirus (PDCoV), and transmissible gastroenteritis virus (TGEV) are the primary enteric coronaviruses responsible for viral diarrhea in piglets. These pathogens frequently co-circulate with porcine
Yinhe Zha +9 more
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Mutations in the macrodomain 1 of nsp3 attenuate PEDV virulence in vivo without impairing in vitro replication [PDF]
Journal of VirologyThe conserved macrodomain 1 (Mac1) within coronavirus nsp3 reverses ADP-ribosylation of proteins and contributes to viral virulence. While Mac1 has been characterized in several coronaviruses, its role in porcine epidemic diarrhea virus (PEDV) remains ...
Mingde Liu +6 more
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Different Infectivity of Swine Enteric Coronaviruses in Cells of Various Species
PathogensSwine enteric coronaviruses (SECoVs), including porcine deltacoronavirus (PDCoV), transmissible gastroenteritis virus (TGEV), porcine epidemic diarrhea virus (PEDV), and swine acute diarrhea syndrome coronavirus (SADS-CoV), have caused high mortality in ...
Zhongyuan Li +4 more
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Canine Enteric Coronaviruses: Emerging Viral Pathogens with Distinct Recombinant Spike Proteins
Viruses, 2014 Canine enteric coronavirus (CCoV) is an alphacoronavirus infecting dogs that is closely related to enteric coronaviruses of cats and pigs. While CCoV has traditionally caused mild gastro-intestinal clinical signs, there are increasing reports of lethal ...
Beth N. Licitra +2 more
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Veterinary ResearchCoronaviruses (CoVs) are emerging pathogens that have been extensively studied over the last twenty years and can cause acute respiratory diseases in humans, as exemplified by the SARS-CoV-2 pandemic.
Manon Delaplace +9 more
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Gasdermin B-mediated pyroptosis as a host defense against swine enteric coronaviruses and its antagonism by PEDV [PDF]
mBioGasdermin B (GSDMB), a member of the spore-forming protein gasdermin (GSDM) family, is critical for inflammation and immunity and has been genetically linked to human diseases.
Yao Yao +8 more
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Porcine epidemic diarrhea virus: a model for coronavirus persistence and immune escape in intensive livestock systems [PDF]
Porcine Health ManagementPorcine epidemic diarrhea virus (PEDV) is an enteric alphacoronavirus that has shifted from a sporadic regional pathogen to a worldwide, persistent virus, despite years of vaccination, biosecurity measures, and monitoring. Since the early 1970s, PEDV has
Leila Wogick, Sagar M. Goyal
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Tight junction protein claudin-1 is a novel internalization factor for swine enteric coronaviruses infection [PDF]
mBioSwine enteric coronaviruses (SeCoVs), including transmissible gastroenteritis virus (TGEV), porcine epidemic diarrhea virus (PEDV), and porcine deltacoronavirus (PDCoV), have been reported to use aminopeptidase N (APN) as a cellular receptor.
Zhongyuan Li +7 more
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