Results 11 to 20 of about 24,819 (205)

Immunochemical activity of Yersinia pseudotuberculosis ompF and ompC porins evaluated by optical trapping

open access: yesИнфекция и иммунитет, 2022
Introduction. Study of features for interacting antigen-antibody system is of great importance for developing new modern tools for diagnostics and therapy of infectious diseases.
Ilya V. Konyshev   +3 more
doaj   +1 more source

Single-channel electrophysiology reveals a distinct and uniform pore complex formed by α-synuclein oligomers in lipid membranes. [PDF]

open access: yes, 2012
Synucleinopathies such as Parkinson's disease, multiple system atrophy and dementia with Lewy bodies are characterized by deposition of aggregated α-synuclein.
Bötzel, Kai   +5 more
core   +8 more sources

A Barrier to Entry: Examining the Bacterial Outer Membrane and Antibiotic Resistance

open access: yesApplied Sciences, 2023
Gram-negative bacteria can resist antibiotics by changing the permeability via their outer membrane. These bacteria have a complex cell envelope that incorporates an outer membrane separating the periplasm from the external environment.
Ishan Ghai
doaj   +1 more source

Induction of Progenitor Exhausted Tissue-Resident Memory CD8+ T Cells Upon Salmonella Typhi Porins Adjuvant Immunization Correlates With Melanoma Control and Anti-PD-1 Immunotherapy Cooperation

open access: yesFrontiers in Immunology, 2020
Immunotherapy has improved the clinical response in melanoma patients, although a relevant percentage of patients still cannot be salvaged. The search for the immune populations that provide the best tumor control and that can be coaxed by immunotherapy ...
Ricardo A. León-Letelier   +12 more
doaj   +1 more source

Roles of the EnvZ/OmpR Two-Component System and Porins in Iron Acquisition in Escherichia coli

open access: yesmBio, 2020
Escherichia coli secretes high-affinity Fe3+ chelators to solubilize and transport chelated Fe3+ via specific outer membrane receptors. In microaerobic and anaerobic growth environments, where the reduced Fe2+ form is predominant, ferrous transport ...
Henri Gerken   +3 more
doaj   +1 more source

The Small RNA NcS25 Regulates Biological Amine-Transporting Outer Membrane Porin BCAL3473 in Burkholderia cenocepacia

open access: yesmSphere, 2023
Regulation of porin expression in bacteria is complex and often involves small-RNA regulators. Several small-RNA regulators have been described for Burkholderia cenocepacia, and this study aimed to characterize the biological role of the conserved small ...
Andrea M. Sass, Tom Coenye
doaj   +1 more source

Antiproliferative effects of porins extracted from Klebsiella pneumoniae on HL-60, NIH/3T3 and Human foreskin fibroblast cell (HFFC) lines measured by ELISA method

open access: yesمجلة مركز بحوث التقنيات الاحيائية, 2010
Approximately, 50% of the dry mass of the outer membrane of gram-negative bacteria consists of proteins, and more than 20 immunochemically distinct proteins (termed outer membrane proteins [OMPs]) have been identified.
Amir H. Al–Shammary   +2 more
doaj   +3 more sources

Genomic Characterization of Mutli-Drug Resistant Pseudomonas aeruginosa Clinical Isolates: Evaluation and Determination of Ceftolozane/Tazobactam Activity and Resistance Mechanisms

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
Resistance to ceftolozane/tazobactam (C/T) in Pseudomonas aeruginosa is a health concern. In this study, we conducted a whole-genome-based molecular characterization to correlate resistance patterns and β-lactamases with C/T resistance among multi-drug ...
Ibrahim Bitar   +7 more
doaj   +1 more source

Porin from Rhodopseudomonas sphaeroides [PDF]

open access: yesJournal of Bacteriology, 1984
A protein homooligomer was purified from both the cell envelope fractions and the saline extracts of Rhodopseudomonas sphaeroides cells. This oligomer exhibited strong porin activity when reconstituted into proteoliposomes with egg phosphatidylcholine. In the saline extracts of both chemotrophically and phototrophically grown cells, the porin oligomer ...
J, Weckesser, L S, Zalman, H, Nikaido
openaire   +2 more sources

High-Level Carbapenem Resistance among OXA-48-Producing Klebsiellapneumoniae with Functional OmpK36 Alterations: Maintenance of Ceftazidime/Avibactam Susceptibility

open access: yesAntibiotics, 2021
The aim of this work was to analyze outer membrane porin-encoding genes (ompK35 and ompK36) in a collection of OXA-48 producing Klebsiella pneumoniae, to assess the effect of porin alterations on the susceptibility to ceftazidime/avibactam, and to ...
Pilar Lumbreras-Iglesias   +4 more
doaj   +1 more source

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