Results 31 to 40 of about 28,026 (256)

Structural Metrics Predict Site-Specific Evolutionary Rate in Membrane Bound Proteins [PDF]

open access: yes, 2016
Membrane proteins are involved in many critical biological processes and mutations are linked to various diseases. We examined how the properties of the location of an amino acid residue within the protein structure dictates the rate at which it evolves.
Du, Xuezhen
core   +1 more source

Trends of the major porin gene (ompF) evolution [PDF]

open access: yes, 2011
OmpF is one of the major general porins of Enterobacteriaceae that belongs to the first line of bacterial defense and interactions with the biotic as well as abiotic environments.
Isaeva, Marina P.   +4 more
core   +1 more source

Genomic Characterization of Mutli-Drug Resistant Pseudomonas aeruginosa Clinical Isolates: Evaluation and Determination of Ceftolozane/Tazobactam Activity and Resistance Mechanisms

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
Resistance to ceftolozane/tazobactam (C/T) in Pseudomonas aeruginosa is a health concern. In this study, we conducted a whole-genome-based molecular characterization to correlate resistance patterns and β-lactamases with C/T resistance among multi-drug ...
Ibrahim Bitar   +7 more
doaj   +1 more source

It's porin' CNTs [PDF]

open access: yesNature Methods, 2014
Lipid-coated carbon nanotubes can insert themselves spontaneously into lipid bilayers and live-cell membranes.
openaire   +2 more sources

Structural analysis of outer membrane beta-stranded porins using B-factor [PDF]

open access: yes, 2009
Computational and statistical analysis has formed a large component of the biophysical efforts put forth to understand protein structure and function, due to the diversity and complexity of their structure.
Abhishek Kumar, S Krishnaswamy
core   +2 more sources

High-Level Carbapenem Resistance among OXA-48-Producing Klebsiellapneumoniae with Functional OmpK36 Alterations: Maintenance of Ceftazidime/Avibactam Susceptibility

open access: yesAntibiotics, 2021
The aim of this work was to analyze outer membrane porin-encoding genes (ompK35 and ompK36) in a collection of OXA-48 producing Klebsiella pneumoniae, to assess the effect of porin alterations on the susceptibility to ceftazidime/avibactam, and to ...
Pilar Lumbreras-Iglesias   +4 more
doaj   +1 more source

Solute channels of the outer membrane: from bacteria to chloroplasts [PDF]

open access: yes, 2007
Chloroplasts, unique organelles of plants, originated from endosymbiosis of an ancestor of today's cyanobacteria with a mitochondria-containing host cell. It is assumed that the outer envelope membrane, which delimits the chloroplast from the surrounding
Aljamal J.A.   +8 more
core   +1 more source

CD4+ and CD8+ Circulating Memory T Cells Are Crucial in the Protection Induced by Vaccination with Salmonella Typhi Porins

open access: yesMicroorganisms, 2021
Salmonella enterica serovar Typhi (S. Typhi) porins, OmpC and OmpF, are potent inducers of the immune response against S. Typhi in mice and humans. Vaccination with porins induces the protection against 500 LD50 of S.
Luis Ontiveros-Padilla   +8 more
doaj   +1 more source

Poly(2-oxazolines) in biological and biomedical application contexts. [PDF]

open access: yes, 2007
Polyoxazolines of various architectures and chemical functionalities can be prepared in a living and therefore controlled manner via cationic ring-opening polymerisation.
Adams, Nico, Schubert, Ulrich S
core   +1 more source

Historical Perspective of Pore-Forming Activity Studies of Voltage-Dependent Anion Channel (Eukaryotic or Mitochondrial Porin) Since Its Discovery in the 70th of the Last Century

open access: yesFrontiers in Physiology, 2021
Eukaryotic porin, also known as Voltage-Dependent Anion Channel (VDAC), is the most frequent protein in the outer membrane of mitochondria that are responsible for cellular respiration.
Roland Benz
doaj   +1 more source

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