Results 61 to 70 of about 28,026 (256)

Solute Transport through Mitochondrial Porins In Vitro and In Vivo

Biomolecules
Mitochondria are most likely descendants of strictly aerobic prokaryotes from the class Alphaproteobacteria. The mitochondrial matrix is surrounded by two membranes according to its relationship with Gram-negative bacteria. Similar to the bacterial outer
Roland Benz
doaj   +1 more source

Evaluation of the Potential Carrier and Controlled Release of Antibiotics by Zinc, Nickel, and Cobalt Ferrite Nanoparticles Encapsulated with Silica and Functionalized with Moxifloxacin Hydrochloride

Particle &Particle Systems Characterization, EarlyView.
The study reveals the inhibitory potential of encapsulated nanoparticles functionalized with moxifloxacin hydrochloride. ABSTRACT Bacterial resistance represents a significant global health threat associated with the development of microbial resistance genes.
Amanda S. Abreu, Stéfanne R. R. Ferreira, Naiara G. Cabral, Romayne P. França, Hanstter H. A. Rezende, Richard Landers, Alexandre Pancotti   +6 more
wiley   +1 more source

Structural and Immunological Characterization of Novel Recombinant MOMP-Based Chlamydial Antigens

Vaccines, 2017
Chlamydia is the most common cause of bacterial sexually transmitted infections worldwide. While infections resolve with antibiotic treatment, this is often neglected in women due to frequent asymptomatic infections, leading to disease progression and ...
Guillermo Madico, Olga Gursky, Jeff Fairman, Paola Massari   +3 more
doaj   +1 more source

Cell entry mechanism of enzymatic bacterial colicins: Porin recruitment and the thermodynamics of receptor binding [PDF]

, 2005
Binding of enzymatic E colicins to the vitamin B-12 receptor, BtuB, is the first stage in a cascade of events that culminate in the translocation of the cytotoxic nuclease into the Escherichia coli cytoplasm and release of its tightly bound immunity ...
Housden, Nicholas G., James, Richard, Kleanthous, Colin, Loftus, Steven R., Moore, Geoffrey R.   +4 more
core   +3 more sources

Atomic‐Precision Symmetry Breaking in Bi‐O‐Ti Sites Enables ROS Generation for Bactericidal and Osteosarcoma Therapy

Rare Metals, EarlyView.
ABSTRACT Photocatalytic therapy, which generates reactive oxygen species (ROS) upon light irradiation, has garnered significant interest for antibacterial and anticancer applications. This study establishes a doping‐engineered photocatalytic platform for antibacterial activity and precision osteosarcoma therapy by atomically constructing asymmetric Bi ...
Jun Gu, Haitao Yuan, Bo Chu, Tianqi Wang, Jin Fan, Xuan Sun, Feng Shi, Qinqin Liu, Xiaojun Feng   +8 more
wiley   +1 more source

Neisseria gonorrhoeae Porin Modulates Phagosome Maturation [PDF]

Journal of Biological Chemistry, 1998
The porin (PorB) of Neisseria gonorrhoeae has been implicated in the pathogenesis of this species. Porin is believed to translocate from the bacterial outer membrane into target cell membranes affecting various cell functions. Here we investigated the effect of porin on phagosome maturation.
Mosleh, I., Huber, L., Steinlein, P., Pasquali, C., Günther, D., Meyer, T.   +5 more
openaire   +3 more sources

SSTAR, a Stand-Alone Easy-To-Use Antimicrobial Resistance Gene Predictor

mSphere, 2016
We present the easy-to-use Sequence Search Tool for Antimicrobial Resistance, SSTAR. It combines a locally executed BLASTN search against a customizable database with an intuitive graphical user interface for identifying antimicrobial resistance (AR ...
Tom J. B. de Man, Brandi M. Limbago
doaj   +1 more source

Bacterial outer membrane vesicles and vaccine applications [PDF]

, 2014
Vaccines based on outer membrane vesicles (OMV) were developed more than 20 years ago against Neisseria meningitidis serogroup B. These nano-sized structures exhibit remarkable potential for immunomodulation of immune responses and delivery of “self ...
Acevedo, Reinaldo, Acosta, Armando, Campa, Concepcion, Cardoso, Daniel, Fernandez, Sonsire, Ferro, Valerie, Garcia, Luis, Perez, Jose Luis, Rosenqvist, Einar, Sarmiento, Maria Elena, Zayas, Caridad   +10 more
core   +2 more sources

From Membrane Composition to Antimicrobial Strategies: Experimental and Computational Approaches to AMP Design and Selectivity

Small, EarlyView.
Antimicrobial peptides (AMPs) are promising candidates for next‐generation antibiotics, acting through mechanisms such as membrane disruption and intracellular targeting. This review examines how variations in bacterial membrane composition critically influence AMP activity.
Paolo Rossetti, Marius F.W. Trollmann, Christina Wichmann, Thomas Gutsmann, Christian Eggeling, Rainer A. Böckmann   +5 more
wiley   +1 more source

Membrane proteins and proteomics: Love is possible, but so difficult [PDF]

, 2009
Despite decades of extensive research, the large-scale analysis of membrane proteins remains a difficult task. This is due to the fact that membrane proteins require a carefully balanced hydrophilic and lipophilic environment, which optimum varies with ...
Adessi, Aebersold, Aivaliotis, Aivaliotis, Alla, Ames, Babu, Bagshaw, Bell, Berlanda-Scorza, Berven, Bierczynska-Krzysik, Bisle, Bjellqvist, Bunai, Bunai, Burré, Buxbaum, Casey, Chevallet, Chevallet, Connolly, Coughenour, Cutillas, Devreese, Eravci, Everberg, Felsted, Ferro, Gatlin, Ghosh, Gyenes, Görg, Hagan, Hahne, Hartinger, Helling, Henningsen, Henzel, Hisabori, Hjelmeland, Huang, Huang, James, Jun, Lasonder, Lescuyer, Liberatori, Lopez, Low, Luche, Lyubimova, Lüddens, MacFarlane, MacFarlane, Matsudaira, McDonough, Miguet, Moebius, Molloy, Molloy, Nandakumar, Natera, Navarre, Ong, Papasotiriou, Pappin, Patton, Pedersen, Peng, Perdew, Phadke, Rabilloud, Rabilloud, Rabilloud, Rabilloud, Rabilloud, Rais, Rubin, Santoni, Santoni, Schindler, Schirle, Schägger, Siroy, Speers, Sweetnam, Switzer, Tastet, Taylor, Towbin, Veith, Washburn, Werner, Wilkins, Williams, Williams, Williams, Wittig, Witzmann, Wu, Yates, Ying, Zahedi   +103 more
core   +4 more sources